152 related articles for article (PubMed ID: 22074424)
1. A prodrug approach to improve the physico-chemical properties and decrease the genotoxicity of nitro compounds.
Chung MC; Bosquesi PL; dos Santos JL
Curr Pharm Des; 2011; 17(32):3515-26. PubMed ID: 22074424
[TBL] [Abstract][Full Text] [Related]
2. Effects of the nitro-group on the mutagenicity and toxicity of some benzamines.
Chung KT; Murdock CA; Zhou Y; Stevens SE; Li YS; Wei CI; Fernando SY; Chou MW
Environ Mol Mutagen; 1996; 27(1):67-74. PubMed ID: 8625950
[TBL] [Abstract][Full Text] [Related]
3. Steady-state and stopped-flow kinetic studies of three Escherichia coli NfsB mutants with enhanced activity for the prodrug CB1954.
Jarrom D; Jaberipour M; Guise CP; Daff S; White SA; Searle PF; Hyde EI
Biochemistry; 2009 Aug; 48(32):7665-72. PubMed ID: 19580253
[TBL] [Abstract][Full Text] [Related]
4. Nitro-Group-Containing Drugs.
Nepali K; Lee HY; Liou JP
J Med Chem; 2019 Mar; 62(6):2851-2893. PubMed ID: 30295477
[TBL] [Abstract][Full Text] [Related]
5. The interaction of nitroaromatic drugs with aminothiols.
Tocher JH; Edwards DI
Biochem Pharmacol; 1995 Oct; 50(9):1367-71. PubMed ID: 7503785
[TBL] [Abstract][Full Text] [Related]
6. Is metronidazole carcinogenic?
Bendesky A; Menéndez D; Ostrosky-Wegman P
Mutat Res; 2002 Jun; 511(2):133-44. PubMed ID: 12052431
[TBL] [Abstract][Full Text] [Related]
7. Nitro reduction as an electronic switch for bioreductive drug activation.
Siim BG; Denny WA; Wilson WR
Oncol Res; 1997; 9(6-7):357-69. PubMed ID: 9406242
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of toxicity of nitro compounds used in the chemotherapy of trichomoniasis.
Moreno SN; Docampo R
Environ Health Perspect; 1985 Dec; 64():199-208. PubMed ID: 3830698
[TBL] [Abstract][Full Text] [Related]
9. Structure-mutagenicity relationships in 2-furylethylene derivatives. A molecular orbital study of the role of nitro groups.
Estrada E
Mutat Res; 1998 Dec; 420(1-3):67-75. PubMed ID: 9838048
[TBL] [Abstract][Full Text] [Related]
10. Electrochemical characteristics of nitroheterocyclic compounds of biological interest. VIII. Stability of nitro radical anions from cyclic voltammetric studies.
Tocher JH; Edwards DI
Free Radic Res Commun; 1992; 16(1):19-25. PubMed ID: 1516846
[TBL] [Abstract][Full Text] [Related]
11. Mechanism of carcinogenesis induced by a veterinary antimicrobial drug, nitrofurazone, via oxidative DNA damage and cell proliferation.
Hiraku Y; Sekine A; Nabeshi H; Midorikawa K; Murata M; Kumagai Y; Kawanishi S
Cancer Lett; 2004 Nov; 215(2):141-50. PubMed ID: 15488632
[TBL] [Abstract][Full Text] [Related]
12. Comparative genotoxic evaluation of 2-furylethylenes and 5-nitrofurans by using the comet assay in TK6 cells.
González Borroto JI; Pérez Machado G; Creus A; Marcos R
Mutagenesis; 2005 May; 20(3):193-7. PubMed ID: 15817571
[TBL] [Abstract][Full Text] [Related]
13. Voltammetric investigation of DNA damage induced by nitrofurazone and short-lived nitro-radicals with the use of an electrochemical DNA biosensor.
Ni Y; Wang P; Kokot S
Biosens Bioelectron; 2012; 38(1):245-51. PubMed ID: 22717476
[TBL] [Abstract][Full Text] [Related]
14. Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form.
Johansson E; Parkinson GN; Denny WA; Neidle S
J Med Chem; 2003 Sep; 46(19):4009-20. PubMed ID: 12954054
[TBL] [Abstract][Full Text] [Related]
15. Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases.
Peñalver P; Belmonte-Reche E; Adán N; Caro M; Mateos-Martín ML; Delgado M; González-Rey E; Morales JC
Eur J Med Chem; 2018 Feb; 146():123-138. PubMed ID: 29407944
[TBL] [Abstract][Full Text] [Related]
16. Reduction of nitroheterocyclic compounds by mammalian tissues in vivo.
Yeung TC; Sudlow G; Koch RL; Goldman P
Biochem Pharmacol; 1983 Jul; 32(14):2249-53. PubMed ID: 6870947
[TBL] [Abstract][Full Text] [Related]
17. The effect of sulfonate leaving groups on the hypoxia-selective toxicity of nitro analogs of the duocarmycins.
Ashoorzadeh A; Atwell GJ; Pruijn FB; Wilson WR; Tercel M; Denny WA; Stevenson RJ
Bioorg Med Chem; 2011 Aug; 19(16):4851-60. PubMed ID: 21767954
[TBL] [Abstract][Full Text] [Related]
18. Indirect electroreduction as pretreatment to enhance biodegradability of metronidazole.
Saidi I; Soutrel I; Floner D; Fourcade F; Bellakhal N; Amrane A; Geneste F
J Hazard Mater; 2014 Aug; 278():172-9. PubMed ID: 24968253
[TBL] [Abstract][Full Text] [Related]
19. Differential In Vitro and In Vivo Toxicities of Antimicrobial Peptide Prodrugs for Potential Use in Cystic Fibrosis.
Forde É; Schütte A; Reeves E; Greene C; Humphreys H; Mall M; Fitzgerald-Hughes D; Devocelle M
Antimicrob Agents Chemother; 2016 May; 60(5):2813-21. PubMed ID: 26902766
[TBL] [Abstract][Full Text] [Related]
20. Biological studies on 2,1-benzisothiazole derivatives. II. Evaluation of antimicrobial and genotoxic properties of bz-nitro-, 3-ethylacetate-, 3-amino- and 3-substituted amino 2,1-benzisothiazoles.
Zani F; Bellotti A; Mazza P
Farmaco; 1994 Nov; 40(11):713-9. PubMed ID: 7832974
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
