These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 22074495)

  • 1. Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation.
    Vo K; Amarasinghe B; Washington K; Gonzalez A; Berlin J; Dang TP
    Mol Cancer; 2011 Nov; 10():138. PubMed ID: 22074495
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells.
    Ponnurangam S; Dandawate PR; Dhar A; Tawfik OW; Parab RR; Mishra PD; Ranadive P; Sharma R; Mahajan G; Umar S; Weir SJ; Sugumar A; Jensen RA; Padhye SB; Balakrishnan A; Anant S; Subramaniam D
    Oncotarget; 2016 Jan; 7(3):3217-32. PubMed ID: 26673007
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.
    Konishi J; Kawaguchi KS; Vo H; Haruki N; Gonzalez A; Carbone DP; Dang TP
    Cancer Res; 2007 Sep; 67(17):8051-7. PubMed ID: 17804716
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting Notch signaling by γ-secretase inhibitor I enhances the cytotoxic effect of 5-FU in gastric cancer.
    Lee HW; Kim SJ; Choi IJ; Song J; Chun KH
    Clin Exp Metastasis; 2015 Aug; 32(6):593-603. PubMed ID: 26134677
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New insights into Notch1 regulation of the PI3K-AKT-mTOR1 signaling axis: targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia.
    Hales EC; Taub JW; Matherly LH
    Cell Signal; 2014 Jan; 26(1):149-61. PubMed ID: 24140475
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rapamycin enhances the anti-tumor effect of gemcitabine in pancreatic cancer cells.
    Okada T; Sawada T; Kubota K
    Hepatogastroenterology; 2007; 54(79):2129-33. PubMed ID: 18251175
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancer.
    Kim SJ; Lee HW; Baek JH; Cho YH; Kang HG; Jeong JS; Song J; Park HS; Chun KH
    Oncogene; 2016 Jan; 35(2):251-60. PubMed ID: 25823029
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Wild-type phosphatase and tensin homolog deleted on chromosome 10 improved the sensitivity of cells to rapamycin through regulating phosphorylation of Akt in esophageal squamous cell carcinoma.
    Lu Z; Wang J; Zheng Y; Yang S; Liu M; Chen X; Wang C; Hou G
    Dis Esophagus; 2017 Feb; 30(2):1-8. PubMed ID: 26725440
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Notch pathway arrests PTEN-deficient advanced prostate cancer by triggering p27-driven cellular senescence.
    Revandkar A; Perciato ML; Toso A; Alajati A; Chen J; Gerber H; Dimitrov M; Rinaldi A; Delaleu N; Pasquini E; D'Antuono R; Pinton S; Losa M; Gnetti L; Arribas A; Fraering P; Bertoni F; Nepveu A; Alimonti A
    Nat Commun; 2016 Dec; 7():13719. PubMed ID: 27941799
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PTEN regulates sensitivity of melanoma cells to RO4929097, the γ-secretase inhibitor.
    Nair JS; Sheikh T; Ho AL; Schwartz GK
    Anticancer Res; 2013 Apr; 33(4):1307-16. PubMed ID: 23564767
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MAML1 regulates cell viability via the NF-κB pathway in cervical cancer cell lines.
    Kuncharin Y; Sangphech N; Kueanjinda P; Bhattarakosol P; Palaga T
    Exp Cell Res; 2011 Aug; 317(13):1830-40. PubMed ID: 21640102
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthetic lethality through combined Notch-epidermal growth factor receptor pathway inhibition in basal-like breast cancer.
    Dong Y; Li A; Wang J; Weber JD; Michel LS
    Cancer Res; 2010 Jul; 70(13):5465-74. PubMed ID: 20570903
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
    Efferson CL; Winkelmann CT; Ware C; Sullivan T; Giampaoli S; Tammam J; Patel S; Mesiti G; Reilly JF; Gibson RE; Buser C; Yeatman T; Coppola D; Winter C; Clark EA; Draetta GF; Strack PR; Majumder PK
    Cancer Res; 2010 Mar; 70(6):2476-84. PubMed ID: 20197467
    [TBL] [Abstract][Full Text] [Related]  

  • 14. γ-Secretase inhibitor enhances antitumour effect of radiation in Notch-expressing lung cancer.
    Mizugaki H; Sakakibara-Konishi J; Ikezawa Y; Kikuchi J; Kikuchi E; Oizumi S; Dang TP; Nishimura M
    Br J Cancer; 2012 Jun; 106(12):1953-9. PubMed ID: 22596234
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of an inhibitor of the γ-secretase complex on proliferation and apoptotic parameters in a FOXL2-mutated granulosa tumor cell line (KGN).
    Irusta G; Pazos MC; Abramovich D; De Zúñiga I; Parborell F; Tesone M
    Biol Reprod; 2013 Jul; 89(1):9. PubMed ID: 23699387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A high Notch pathway activation predicts response to γ secretase inhibitors in proneural subtype of glioma tumor-initiating cells.
    Saito N; Fu J; Zheng S; Yao J; Wang S; Liu DD; Yuan Y; Sulman EP; Lang FF; Colman H; Verhaak RG; Yung WK; Koul D
    Stem Cells; 2014 Jan; 32(1):301-12. PubMed ID: 24038660
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NOTCH and PTEN in prostate cancer.
    Bertrand FE; McCubrey JA; Angus CW; Nutter JM; Sigounas G
    Adv Biol Regul; 2014 Sep; 56():51-65. PubMed ID: 24933481
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined antitumor effect of γ-secretase inhibitor and ABT-737 in Notch-expressing non-small cell lung cancer.
    Sakakibara-Konishi J; Ikezawa Y; Oizumi S; Kikuchi J; Kikuchi E; Mizugaki H; Kinoshita I; Dosaka-Akita H; Nishimura M
    Int J Clin Oncol; 2017 Apr; 22(2):257-268. PubMed ID: 27816990
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PIK3CA/PTEN mutations and Akt activation as markers of sensitivity to allosteric mTOR inhibitors.
    Meric-Bernstam F; Akcakanat A; Chen H; Do KA; Sangai T; Adkins F; Gonzalez-Angulo AM; Rashid A; Crosby K; Dong M; Phan AT; Wolff RA; Gupta S; Mills GB; Yao J
    Clin Cancer Res; 2012 Mar; 18(6):1777-89. PubMed ID: 22422409
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.
    Clementz AG; Rogowski A; Pandya K; Miele L; Osipo C
    Breast Cancer Res; 2011 Jun; 13(3):R63. PubMed ID: 21679465
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.