362 related articles for article (PubMed ID: 22075993)
1. Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.
Wollenick K; Hu J; Kristiansen G; Schraml P; Rehrauer H; Berchner-Pfannschmidt U; Fandrey J; Wenger RH; Stiehl DP
Nucleic Acids Res; 2012 Mar; 40(5):1928-43. PubMed ID: 22075993
[TBL] [Abstract][Full Text] [Related]
2. Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.
Spinella F; Rosanò L; Del Duca M; Di Castro V; Nicotra MR; Natali PG; Bagnato A
PLoS One; 2010 Jun; 5(6):e11241. PubMed ID: 20574527
[TBL] [Abstract][Full Text] [Related]
3. Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia.
Fujita N; Markova D; Anderson DG; Chiba K; Toyama Y; Shapiro IM; Risbud MV
J Biol Chem; 2012 May; 287(20):16975-86. PubMed ID: 22451659
[TBL] [Abstract][Full Text] [Related]
4. Increased activation of the hypoxia-inducible factor pathway in varicose veins.
Lim CS; Kiriakidis S; Paleolog EM; Davies AH
J Vasc Surg; 2012 May; 55(5):1427-39. PubMed ID: 22277691
[TBL] [Abstract][Full Text] [Related]
5. Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.
Marxsen JH; Stengel P; Doege K; Heikkinen P; Jokilehto T; Wagner T; Jelkmann W; Jaakkola P; Metzen E
Biochem J; 2004 Aug; 381(Pt 3):761-7. PubMed ID: 15104534
[TBL] [Abstract][Full Text] [Related]
6. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
Aprelikova O; Chandramouli GV; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
J Cell Biochem; 2004 Jun; 92(3):491-501. PubMed ID: 15156561
[TBL] [Abstract][Full Text] [Related]
7. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
Chintala S; Najrana T; Toth K; Cao S; Durrani FA; Pili R; Rustum YM
BMC Cancer; 2012 Jul; 12():293. PubMed ID: 22804960
[TBL] [Abstract][Full Text] [Related]
8. Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors.
Henze AT; Riedel J; Diem T; Wenner J; Flamme I; Pouyseggur J; Plate KH; Acker T
Cancer Res; 2010 Jan; 70(1):357-66. PubMed ID: 20028863
[TBL] [Abstract][Full Text] [Related]
9. Oxygen sensing by the prolyl-4-hydroxylase PHD2 within the nuclear compartment and the influence of compartmentalisation on HIF-1 signalling.
Pientka FK; Hu J; Schindler SG; Brix B; Thiel A; Jöhren O; Fandrey J; Berchner-Pfannschmidt U; Depping R
J Cell Sci; 2012 Nov; 125(Pt 21):5168-76. PubMed ID: 22946054
[TBL] [Abstract][Full Text] [Related]
10. Neuron-specific prolyl-4-hydroxylase domain 2 knockout reduces brain injury after transient cerebral ischemia.
Kunze R; Zhou W; Veltkamp R; Wielockx B; Breier G; Marti HH
Stroke; 2012 Oct; 43(10):2748-56. PubMed ID: 22933585
[TBL] [Abstract][Full Text] [Related]
11. The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability.
Barth S; Nesper J; Hasgall PA; Wirthner R; Nytko KJ; Edlich F; Katschinski DM; Stiehl DP; Wenger RH; Camenisch G
Mol Cell Biol; 2007 May; 27(10):3758-68. PubMed ID: 17353276
[TBL] [Abstract][Full Text] [Related]
12. Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300.
Ruas JL; Berchner-Pfannschmidt U; Malik S; Gradin K; Fandrey J; Roeder RG; Pereira T; Poellinger L
J Biol Chem; 2010 Jan; 285(4):2601-9. PubMed ID: 19880525
[TBL] [Abstract][Full Text] [Related]
13. Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor.
Appelhoff RJ; Tian YM; Raval RR; Turley H; Harris AL; Pugh CW; Ratcliffe PJ; Gleadle JM
J Biol Chem; 2004 Sep; 279(37):38458-65. PubMed ID: 15247232
[TBL] [Abstract][Full Text] [Related]
14. Class I and IIa HDACs Mediate HIF-1α Stability Through PHD2-Dependent Mechanism, While HDAC6, a Class IIb Member, Promotes HIF-1α Transcriptional Activity in Nucleus Pulposus Cells of the Intervertebral Disc.
Schoepflin ZR; Shapiro IM; Risbud MV
J Bone Miner Res; 2016 Jun; 31(6):1287-99. PubMed ID: 26765925
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of Endothelial PHD2 Suppresses Post-Ischemic Kidney Inflammation through Hypoxia-Inducible Factor-1.
Rajendran G; Schonfeld MP; Tiwari R; Huang S; Torosyan R; Fields T; Park J; Susztak K; Kapitsinou PP
J Am Soc Nephrol; 2020 Mar; 31(3):501-516. PubMed ID: 31996410
[TBL] [Abstract][Full Text] [Related]
16. Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection.
Aprelikova O; Wood M; Tackett S; Chandramouli GV; Barrett JC
Cancer Res; 2006 Jun; 66(11):5641-7. PubMed ID: 16740701
[TBL] [Abstract][Full Text] [Related]
17. Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
Li J; Yuan W; Jiang S; Ye W; Yang H; Shapiro IM; Risbud MV
J Biol Chem; 2015 Mar; 290(11):7195-207. PubMed ID: 25635047
[TBL] [Abstract][Full Text] [Related]
18. Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression.
McMahon S; Charbonneau M; Grandmont S; Richard DE; Dubois CM
J Biol Chem; 2006 Aug; 281(34):24171-81. PubMed ID: 16815840
[TBL] [Abstract][Full Text] [Related]
19. Hypoxia-inducible factor prolyl-hydroxylase 2 senses high-salt intake to increase hypoxia inducible factor 1alpha levels in the renal medulla.
Wang Z; Zhu Q; Xia M; Li PL; Hinton SJ; Li N
Hypertension; 2010 May; 55(5):1129-36. PubMed ID: 20308610
[TBL] [Abstract][Full Text] [Related]
20. Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system.
Stiehl DP; Wirthner R; Köditz J; Spielmann P; Camenisch G; Wenger RH
J Biol Chem; 2006 Aug; 281(33):23482-91. PubMed ID: 16790428
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]