These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 22079344)

  • 1. The enzymatic activity of human aldehyde dehydrogenases 1A2 and 2 (ALDH1A2 and ALDH2) is detected by Aldefluor, inhibited by diethylaminobenzaldehyde and has significant effects on cell proliferation and drug resistance.
    Moreb JS; Ucar D; Han S; Amory JK; Goldstein AS; Ostmark B; Chang LJ
    Chem Biol Interact; 2012 Jan; 195(1):52-60. PubMed ID: 22079344
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aldehyde dehydrogenase activity plays a Key role in the aggressive phenotype of neuroblastoma.
    Flahaut M; Jauquier N; Chevalier N; Nardou K; Balmas Bourloud K; Joseph JM; Barras D; Widmann C; Gross N; Renella R; Mühlethaler-Mottet A
    BMC Cancer; 2016 Oct; 16(1):781. PubMed ID: 27724856
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heterogeneity of aldehyde dehydrogenase expression in lung cancer cell lines is revealed by Aldefluor flow cytometry-based assay.
    Moreb JS; Zucali JR; Ostmark B; Benson NA
    Cytometry B Clin Cytom; 2007 Jul; 72(4):281-9. PubMed ID: 17111384
    [TBL] [Abstract][Full Text] [Related]  

  • 4. N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes.
    Morgan CA; Parajuli B; Buchman CD; Dria K; Hurley TD
    Chem Biol Interact; 2015 Jun; 234():18-28. PubMed ID: 25512087
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives.
    Buchman CD; Hurley TD
    J Med Chem; 2017 Mar; 60(6):2439-2455. PubMed ID: 28219011
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of ALDH1A1 activity decreases expression of drug transporters and reduces chemotherapy resistance in ovarian cancer cell lines.
    Januchowski R; Wojtowicz K; Sterzyſska K; Sosiſska P; Andrzejewska M; Zawierucha P; Nowicki M; Zabel M
    Int J Biochem Cell Biol; 2016 Sep; 78():248-259. PubMed ID: 27443528
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of aldehyde dehydrogenases of the 1A subfamily as putative anticancer agents: Kinetic characterization and effect on human cancer cells.
    Jiménez R; Pequerul R; Amor A; Lorenzo J; Metwally K; Avilés FX; Parés X; Farrés J
    Chem Biol Interact; 2019 Jun; 306():123-130. PubMed ID: 30958995
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ALDH1A inhibition sensitizes colon cancer cells to chemotherapy.
    Kozovska Z; Patsalias A; Bajzik V; Durinikova E; Demkova L; Jargasova S; Smolkova B; Plava J; Kucerova L; Matuskova M
    BMC Cancer; 2018 Jun; 18(1):656. PubMed ID: 29902974
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity.
    Muramoto GG; Russell JL; Safi R; Salter AB; Himburg HA; Daher P; Meadows SK; Doan P; Storms RW; Chao NJ; McDonnell DP; Chute JP
    Stem Cells; 2010 Mar; 28(3):523-34. PubMed ID: 20054864
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of recombinant human mitochondrial and cytosolic aldehyde dehydrogenases by two candidates for the active metabolites of disulfiram.
    Lam JP; Mays DC; Lipsky JJ
    Biochemistry; 1997 Nov; 36(44):13748-54. PubMed ID: 9354647
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct expression patterns and roles of aldehyde dehydrogenases in normal oral mucosa keratinocytes: differential inhibitory effects of a pharmacological inhibitor and RNAi-mediated knockdown on cellular phenotype and epithelial morphology.
    Kato H; Izumi K; Saito T; Ohnuki H; Terada M; Kawano Y; Nozawa-Inoue K; Saito C; Maeda T
    Histochem Cell Biol; 2013 Jun; 139(6):847-62. PubMed ID: 23250514
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of aldehyde dehydrogenase (ALDH) activity reduces chemotherapy and radiation resistance of stem-like ALDHhiCD44⁺ human breast cancer cells.
    Croker AK; Allan AL
    Breast Cancer Res Treat; 2012 May; 133(1):75-87. PubMed ID: 21818590
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting ALDH(bright) human carcinoma-initiating cells with ALDH1A1-specific CD8⁺ T cells.
    Visus C; Wang Y; Lozano-Leon A; Ferris RL; Silver S; Szczepanski MJ; Brand RE; Ferrone CR; Whiteside TL; Ferrone S; DeLeo AB; Wang X
    Clin Cancer Res; 2011 Oct; 17(19):6174-84. PubMed ID: 21856769
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity.
    Parajuli B; Georgiadis TM; Fishel ML; Hurley TD
    Chembiochem; 2014 Mar; 15(5):701-12. PubMed ID: 24677340
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors.
    Buchman CD; Mahalingan KK; Hurley TD
    Chem Biol Interact; 2015 Jun; 234():38-44. PubMed ID: 25641190
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Overexpression of the human aldehyde dehydrogenase class I results in increased resistance to 4-hydroperoxycyclophosphamide.
    Moreb J; Schweder M; Suresh A; Zucali JR
    Cancer Gene Ther; 1996; 3(1):24-30. PubMed ID: 8785707
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of cancer-type specific expression patterns for active aldehyde dehydrogenase (ALDH) isoforms in ALDEFLUOR assay.
    Zhou L; Sheng D; Wang D; Ma W; Deng Q; Deng L; Liu S
    Cell Biol Toxicol; 2019 Apr; 35(2):161-177. PubMed ID: 30220009
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aldehyde dehydrogenase activity plays no functional role in stem cell-like properties in anaplastic thyroid cancer cell lines.
    Shimamura M; Kurashige T; Mitsutake N; Nagayama Y
    Endocrine; 2017 Mar; 55(3):934-943. PubMed ID: 28040834
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH(high)CD44(+) phenotype and sphere-forming capacity.
    Cortes-Dericks L; Froment L; Boesch R; Schmid RA; Karoubi G
    BMC Cancer; 2014 Apr; 14():304. PubMed ID: 24884875
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Differential Functional Roles of ALDH1A1 and ALDH1A3 in Mediating Metastatic Behavior and Therapy Resistance of Human Breast Cancer Cells.
    Croker AK; Rodriguez-Torres M; Xia Y; Pardhan S; Leong HS; Lewis JD; Allan AL
    Int J Mol Sci; 2017 Sep; 18(10):. PubMed ID: 28937653
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.