621 related articles for article (PubMed ID: 22079759)
1. Synthesis and biological evaluations of novel indenoisoquinolines as topoisomerase I inhibitors.
Zhang X; Wang R; Zhao L; Lu N; Wang J; You Q; Li Z; Guo Q
Bioorg Med Chem Lett; 2012 Jan; 22(2):1276-81. PubMed ID: 22079759
[TBL] [Abstract][Full Text] [Related]
2. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
Cheng P; Zhu L; Guo W; Liu W; Yao J; Dong G; Zhang Y; Zhuang C; Sheng C; Miao Z; Zhang W
J Enzyme Inhib Med Chem; 2012 Jun; 27(3):437-42. PubMed ID: 21770860
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of 3-substituted indenoisoquinoline derivatives as topoisomerase I inhibitors.
Zhao Q; Xu X; Xie Z; Liu X; You Q; Guo Q; Zhong Y; Li Z
Bioorg Med Chem Lett; 2016 Feb; 26(3):1068-1072. PubMed ID: 26725027
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles.
Singh M; Tandon V
Eur J Med Chem; 2011 Feb; 46(2):659-69. PubMed ID: 21186067
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of benzo[3,4]azepino[1,2-b]isoquinolin-9-ones from 3-arylisoquinolines via ring closing metathesis and evaluation of topoisomerase I inhibitory activity, cytotoxicity and docking study.
Van HT; Khadka DB; Yang SH; Le TN; Cho SH; Zhao C; Lee IS; Kwon Y; Lee KT; Kim YC; Cho WJ
Bioorg Med Chem; 2011 Sep; 19(18):5311-20. PubMed ID: 21873069
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and systematic evaluation of cytotoxic 3-heteroarylisoquinolinamines as topoisomerases inhibitors.
My Van HT; Woo H; Jeong HM; Khadka DB; Yang SH; Zhao C; Jin Y; Lee ES; Youl Lee K; Kwon Y; Cho WJ
Eur J Med Chem; 2014 Jul; 82():181-94. PubMed ID: 24904965
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of nitrated indenoisoquinolines as topoisomerase I inhibitors.
Morrell A; Antony S; Kohlhagen G; Pommier Y; Cushman M
Bioorg Med Chem Lett; 2004 Jul; 14(14):3659-63. PubMed ID: 15203138
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, and biological evaluation of cytotoxic 11-alkenylindenoisoquinoline topoisomerase I inhibitors and indenoisoquinoline-camptothecin hybrids.
Fox BM; Xiao X; Antony S; Kohlhagen G; Pommier Y; Staker BL; Stewart L; Cushman M
J Med Chem; 2003 Jul; 46(15):3275-82. PubMed ID: 12852757
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, cytotoxicity and topoisomerase inhibition properties of multifarious aminoalkylated indeno[1,2-c]isoquinolin-5,11-diones.
Ahn G; Schifano-Faux N; Goossens JF; Baldeyrou B; Couture A; Grandclaudon P; Lansiaux A; Ryckebusch A
Bioorg Med Chem Lett; 2011 Apr; 21(8):2259-63. PubMed ID: 21439821
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of indenoisoquinolines that inhibit both tyrosyl-DNA phosphodiesterase I (Tdp1) and topoisomerase I (Top1).
Conda-Sheridan M; Reddy PV; Morrell A; Cobb BT; Marchand C; Agama K; Chergui A; Renaud A; Stephen AG; Bindu LK; Pommier Y; Cushman M
J Med Chem; 2013 Jan; 56(1):182-200. PubMed ID: 23259865
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors.
Khadka DB; Park S; Jin Y; Han J; Kwon Y; Cho WJ
Eur J Med Chem; 2018 Jan; 143():200-215. PubMed ID: 29174815
[TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling.
Le TN; Yang SH; Khadka DB; Van HT; Cho SH; Kwon Y; Lee ES; Lee KT; Cho WJ
Bioorg Med Chem; 2011 Jul; 19(14):4399-404. PubMed ID: 21684168
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, Molecular Docking and Biological Evaluation of Quinolone Derivatives as Novel Anticancer Agents.
Li J; Zheng TC; Jin Y; Xu JG; Yu JG; Lv YW
Chem Pharm Bull (Tokyo); 2018 Jan; 66(1):55-60. PubMed ID: 29118308
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and evaluation of novel ellipticines as potential anti-cancer agents.
Deane FM; O'Sullivan EC; Maguire AR; Gilbert J; Sakoff JA; McCluskey A; McCarthy FO
Org Biomol Chem; 2013 Feb; 11(8):1334-44. PubMed ID: 23314103
[TBL] [Abstract][Full Text] [Related]
15. Discovery of potent indenoisoquinoline topoisomerase I poisons lacking the 3-nitro toxicophore.
Beck DE; Abdelmalak M; Lv W; Reddy PV; Tender GS; O'Neill E; Agama K; Marchand C; Pommier Y; Cushman M
J Med Chem; 2015 May; 58(9):3997-4015. PubMed ID: 25909279
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of N-substituted benzo[c]phenanthrolines and benzo[c]phenanthrolinones as antiproliferative agents.
Genès C; Lenglet G; Depauw S; Nhili R; Prado S; David-Cordonnier MH; Michel S; Tillequin F; Porée FH
Eur J Med Chem; 2011 Jun; 46(6):2117-31. PubMed ID: 21435753
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors.
Zhang C; Li S; Ji L; Liu S; Li Z; Li S; Meng X
Bioorg Med Chem Lett; 2015 Oct; 25(20):4693-6. PubMed ID: 26384290
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, topoisomerase-targeting activity and growth inhibition of lycobetaine analogs.
Baechler SA; Fehr M; Habermeyer M; Hofmann A; Merz KH; Fiebig HH; Marko D; Eisenbrand G
Bioorg Med Chem; 2013 Feb; 21(3):814-23. PubMed ID: 23266176
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and anticancer activity of simplified indenoisoquinoline topoisomerase I inhibitors lacking substituents on the aromatic rings.
Nagarajan M; Morrell A; Fort BC; Meckley MR; Antony S; Kohlhagen G; Pommier Y; Cushman M
J Med Chem; 2004 Nov; 47(23):5651-61. PubMed ID: 15509164
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]