475 related articles for article (PubMed ID: 22083280)
1. Simvastatin ameliorates angiotensin II-induced endothelial dysfunction through restoration of Rho-BH4-eNOS-NO pathway.
Zhang Z; Wang M; Xue SJ; Liu DH; Tang YB
Cardiovasc Drugs Ther; 2012 Feb; 26(1):31-40. PubMed ID: 22083280
[TBL] [Abstract][Full Text] [Related]
2. Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.
Zheng JS; Yang XQ; Lookingland KJ; Fink GD; Hesslinger C; Kapatos G; Kovesdi I; Chen AF
Circulation; 2003 Sep; 108(10):1238-45. PubMed ID: 12925450
[TBL] [Abstract][Full Text] [Related]
3. HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells.
Hattori Y; Nakanishi N; Akimoto K; Yoshida M; Kasai K
Arterioscler Thromb Vasc Biol; 2003 Feb; 23(2):176-82. PubMed ID: 12588756
[TBL] [Abstract][Full Text] [Related]
4. Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.
Du YH; Guan YY; Alp NJ; Channon KM; Chen AF
Circulation; 2008 Feb; 117(8):1045-54. PubMed ID: 18268143
[TBL] [Abstract][Full Text] [Related]
5. Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
Chuaiphichai S; McNeill E; Douglas G; Crabtree MJ; Bendall JK; Hale AB; Alp NJ; Channon KM
Hypertension; 2014 Sep; 64(3):530-40. PubMed ID: 24777984
[TBL] [Abstract][Full Text] [Related]
6. GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
Cai S; Alp NJ; McDonald D; Smith I; Kay J; Canevari L; Heales S; Channon KM
Cardiovasc Res; 2002 Sep; 55(4):838-49. PubMed ID: 12176133
[TBL] [Abstract][Full Text] [Related]
7. Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.
Crabtree MJ; Tatham AL; Hale AB; Alp NJ; Channon KM
J Biol Chem; 2009 Oct; 284(41):28128-28136. PubMed ID: 19666465
[TBL] [Abstract][Full Text] [Related]
8. Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice.
Adlam D; Bendall JK; De Bono JP; Alp NJ; Khoo J; Nicoli T; Yokoyama M; Kawashima S; Channon KM
Exp Physiol; 2007 Jan; 92(1):119-26. PubMed ID: 17012144
[TBL] [Abstract][Full Text] [Related]
9. A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.
Chuaiphichai S; Crabtree MJ; Mcneill E; Hale AB; Trelfa L; Channon KM; Douglas G
Br J Pharmacol; 2017 Apr; 174(8):657-671. PubMed ID: 28128438
[TBL] [Abstract][Full Text] [Related]
10. Acute inhibition of guanosine triphosphate cyclohydrolase 1 uncouples endothelial nitric oxide synthase and elevates blood pressure.
Wang S; Xu J; Song P; Wu Y; Zhang J; Chul Choi H; Zou MH
Hypertension; 2008 Sep; 52(3):484-90. PubMed ID: 18645049
[TBL] [Abstract][Full Text] [Related]
11. Essential role of microRNA-155 in regulating endothelium-dependent vasorelaxation by targeting endothelial nitric oxide synthase.
Sun HX; Zeng DY; Li RT; Pang RP; Yang H; Hu YL; Zhang Q; Jiang Y; Huang LY; Tang YB; Yan GJ; Zhou JG
Hypertension; 2012 Dec; 60(6):1407-14. PubMed ID: 23108656
[TBL] [Abstract][Full Text] [Related]
12. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells.
Shimizu S; Shiota K; Yamamoto S; Miyasaka Y; Ishii M; Watabe T; Nishida M; Mori Y; Yamamoto T; Kiuchi Y
Free Radic Biol Med; 2003 May; 34(10):1343-52. PubMed ID: 12726922
[TBL] [Abstract][Full Text] [Related]
13. Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.
Cai S; Khoo J; Channon KM
Cardiovasc Res; 2005 Mar; 65(4):823-31. PubMed ID: 15721862
[TBL] [Abstract][Full Text] [Related]
14. Tyrosine nitration of PA700 activates the 26S proteasome to induce endothelial dysfunction in mice with angiotensin II-induced hypertension.
Xu J; Wang S; Wu Y; Song P; Zou MH
Hypertension; 2009 Sep; 54(3):625-32. PubMed ID: 19597039
[TBL] [Abstract][Full Text] [Related]
15. Cigarette smoke constituents cause endothelial nitric oxide synthase dysfunction and uncoupling due to depletion of tetrahydrobiopterin with degradation of GTP cyclohydrolase.
Abdelghany TM; Ismail RS; Mansoor FA; Zweier JR; Lowe F; Zweier JL
Nitric Oxide; 2018 Jun; 76():113-121. PubMed ID: 29524646
[TBL] [Abstract][Full Text] [Related]
16. Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells.
Sugiyama T; Levy BD; Michel T
J Biol Chem; 2009 May; 284(19):12691-700. PubMed ID: 19286667
[TBL] [Abstract][Full Text] [Related]
17. Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I.
Santhanam AV; d'Uscio LV; Katusic ZS
Brain Res; 2015 Nov; 1625():198-205. PubMed ID: 26343845
[TBL] [Abstract][Full Text] [Related]
18. Tetrahydrobiopterin prevents endothelial dysfunction and restores adiponectin levels in rats.
Wang X; Hattori Y; Satoh H; Iwata C; Banba N; Monden T; Uchida K; Kamikawa Y; Kasai K
Eur J Pharmacol; 2007 Jan; 555(1):48-53. PubMed ID: 17098227
[TBL] [Abstract][Full Text] [Related]
19. The eNOS cofactor tetrahydrobiopterin improves endothelial dysfunction in livers of rats with CCl4 cirrhosis.
Matei V; Rodríguez-Vilarrupla A; Deulofeu R; Colomer D; Fernández M; Bosch J; Garcia-Pagán JC
Hepatology; 2006 Jul; 44(1):44-52. PubMed ID: 16799985
[TBL] [Abstract][Full Text] [Related]
20. Role of tetrahydrobiopterin in pulmonary vascular remodelling associated with pulmonary fibrosis.
Almudéver P; Milara J; De Diego A; Serrano-Mollar A; Xaubet A; Perez-Vizcaino F; Cogolludo A; Cortijo J
Thorax; 2013 Oct; 68(10):938-48. PubMed ID: 23739137
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
