BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 22083890)

  • 1. Interaction of hesperetin glucuronide conjugates with human BCRP, MRP2 and MRP3 as detected in membrane vesicles of overexpressing baculovirus-infected Sf9 cells.
    Brand W; Oosterhuis B; Krajcsi P; Barron D; Dionisi F; van Bladeren PJ; Rietjens IM; Williamson G
    Biopharm Drug Dispos; 2011 Dec; 32(9):530-5. PubMed ID: 22083890
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport.
    Järvinen E; Troberg J; Kidron H; Finel M
    Mol Pharm; 2017 Oct; 14(10):3299-3311. PubMed ID: 28850245
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions.
    Breedveld P; Zelcer N; Pluim D; Sönmezer O; Tibben MM; Beijnen JH; Schinkel AH; van Tellingen O; Borst P; Schellens JH
    Cancer Res; 2004 Aug; 64(16):5804-11. PubMed ID: 15313923
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A new mechanism for increasing the oral bioavailability of scutellarin with Cremophor EL: Activation of MRP3 with concurrent inhibition of MRP2 and BCRP.
    Xiao L; Yi T; Chen M; Lam CW; Zhou H
    Eur J Pharm Sci; 2016 Oct; 93():456-67. PubMed ID: 27586020
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolism and transport of the citrus flavonoid hesperetin in Caco-2 cell monolayers.
    Brand W; van der Wel PA; Rein MJ; Barron D; Williamson G; van Bladeren PJ; Rietjens IM
    Drug Metab Dispos; 2008 Sep; 36(9):1794-802. PubMed ID: 18515333
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of the role of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated protein 4 (MRP4/ABCC4) in the urinary excretion of sulfate and glucuronide metabolites of edaravone (MCI-186; 3-methyl-1-phenyl-2-pyrazolin-5-one).
    Mizuno N; Takahashi T; Kusuhara H; Schuetz JD; Niwa T; Sugiyama Y
    Drug Metab Dispos; 2007 Nov; 35(11):2045-52. PubMed ID: 17682070
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemical inhibition and stable knock-down of efflux transporters leads to reduced glucuronidation of wushanicaritin in UGT1A1-overexpressing HeLa cells: the role of breast cancer resistance protein (BCRP) and multidrug resistance-associated proteins (MRPs) in the excretion of glucuronides.
    Qin Z; Li S; Yao Z; Hong X; Wu B; Krausz KW; Gonzalez FJ; Gao H; Yao X
    Food Funct; 2018 Mar; 9(3):1410-1423. PubMed ID: 29318243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP.
    Järvinen E; Deng F; Kidron H; Finel M
    J Steroid Biochem Mol Biol; 2018 Apr; 178():99-107. PubMed ID: 29175180
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology.
    Andersen V; Svenningsen K; Knudsen LA; Hansen AK; Holmskov U; Stensballe A; Vogel U
    World J Gastroenterol; 2015 Nov; 21(41):11862-76. PubMed ID: 26557010
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Membrane transport of dietary phenethyl isothiocyanate by ABCG2 (breast cancer resistance protein).
    Ji Y; Morris ME
    Mol Pharm; 2005; 2(5):414-9. PubMed ID: 16196494
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Efflux transport of nicotine, cotinine and trans-3'-hydroxycotinine glucuronides by human hepatic transporters.
    Järvinen E; Sjöstedt N; Koenderink JB; Kidron H; Finel M
    Basic Clin Pharmacol Toxicol; 2019 Dec; 125(6):490-498. PubMed ID: 31237077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of chrysin glucuronidation in UGT1A1-overexpressing HeLa cells: elucidating the transporters responsible for efflux of glucuronide.
    Quan E; Wang H; Dong D; Zhang X; Wu B
    Drug Metab Dispos; 2015 Apr; 43(4):433-43. PubMed ID: 25595598
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cholesterol potentiates ABCG2 activity in a heterologous expression system: improved in vitro model to study function of human ABCG2.
    Pál A; Méhn D; Molnár E; Gedey S; Mészáros P; Nagy T; Glavinas H; Janáky T; von Richter O; Báthori G; Szente L; Krajcsi P
    J Pharmacol Exp Ther; 2007 Jun; 321(3):1085-94. PubMed ID: 17347325
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of hydroxycinnamic acids and their conjugates with organic anion transporters and ATP-binding cassette transporters.
    Wong CC; Barron D; Orfila C; Dionisi F; Krajcsi P; Williamson G
    Mol Nutr Food Res; 2011 Jul; 55(7):979-88. PubMed ID: 21538853
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High-activity p-glycoprotein, multidrug resistance protein 2, and breast cancer resistance protein membrane vesicles prepared from transiently transfected human embryonic kidney 293-epstein-barr virus nuclear antigen cells.
    Karlsson JE; Heddle C; Rozkov A; Rotticci-Mulder J; Tuvesson O; Hilgendorf C; Andersson TB
    Drug Metab Dispos; 2010 Apr; 38(4):705-14. PubMed ID: 20071452
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibitory effects of terpenoids on multidrug resistance-associated protein 2- and breast cancer resistance protein-mediated transport.
    Yoshida N; Takada T; Yamamura Y; Adachi I; Suzuki H; Kawakami J
    Drug Metab Dispos; 2008 Jul; 36(7):1206-11. PubMed ID: 18436619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Substrate and method dependent inhibition of three ABC-transporters (MDR1, BCRP, and MRP2).
    Pedersen JM; Khan EK; Bergström CAS; Palm J; Hoogstraate J; Artursson P
    Eur J Pharm Sci; 2017 May; 103():70-76. PubMed ID: 28263911
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Human efflux transport of testosterone, epitestosterone and other androgen glucuronides.
    Järvinen E; Kidron H; Finel M
    J Steroid Biochem Mol Biol; 2020 Mar; 197():105518. PubMed ID: 31704245
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effect of co-administered flavonoids on the metabolism of hesperetin and the disposition of its metabolites in Caco-2 cell monolayers.
    Brand W; Padilla B; van Bladeren PJ; Williamson G; Rietjens IM
    Mol Nutr Food Res; 2010 Jun; 54(6):851-60. PubMed ID: 20112299
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibitory potential of tuberculosis drugs on ATP-binding cassette drug transporters.
    Te Brake LH; Russel FG; van den Heuvel JJ; de Knegt GJ; de Steenwinkel JE; Burger DM; Aarnoutse RE; Koenderink JB
    Tuberculosis (Edinb); 2016 Jan; 96():150-7. PubMed ID: 26682943
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.