These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 22085717)

  • 1. Breast cancer metastasis suppressor 1 (BRMS1) is destabilized by the Cul3-SPOP E3 ubiquitin ligase complex.
    Kim B; Nam HJ; Pyo KE; Jang MJ; Kim IS; Kim D; Boo K; Lee SH; Yoon JB; Baek SH; Kim JH
    Biochem Biophys Res Commun; 2011 Dec; 415(4):720-6. PubMed ID: 22085717
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6.
    Tan Y; Ci Y; Dai X; Wu F; Guo J; Liu D; North BJ; Huo J; Zhang J
    Oncotarget; 2017 Jul; 8(29):47890-47901. PubMed ID: 28599312
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Coordinated activation of the nuclear ubiquitin ligase Cul3-SPOP by the generation of phosphatidylinositol 5-phosphate.
    Bunce MW; Boronenkov IV; Anderson RA
    J Biol Chem; 2008 Mar; 283(13):8678-86. PubMed ID: 18218622
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1.
    Li C; Ao J; Fu J; Lee DF; Xu J; Lonard D; O'Malley BW
    Oncogene; 2011 Oct; 30(42):4350-64. PubMed ID: 21577200
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase.
    Errington WJ; Khan MQ; Bueler SA; Rubinstein JL; Chakrabartty A; Privé GG
    Structure; 2012 Jul; 20(7):1141-53. PubMed ID: 22632832
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase.
    Kwon JE; La M; Oh KH; Oh YM; Kim GR; Seol JH; Baek SH; Chiba T; Tanaka K; Bang OS; Joe CO; Chung CH
    J Biol Chem; 2006 May; 281(18):12664-72. PubMed ID: 16524876
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
    Zhuang M; Calabrese MF; Liu J; Waddell MB; Nourse A; Hammel M; Miller DJ; Walden H; Duda DM; Seyedin SN; Hoggard T; Harper JW; White KP; Schulman BA
    Mol Cell; 2009 Oct; 36(1):39-50. PubMed ID: 19818708
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel insights into the SPOP E3 ubiquitin ligase: From the regulation of molecular mechanisms to tumorigenesis.
    Li XM; Wu HL; Xia QD; Zhou P; Wang SG; Yu X; Hu J
    Biomed Pharmacother; 2022 May; 149():112882. PubMed ID: 35364375
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cullin 3 and Its Role in Tumorigenesis.
    Chen RH
    Adv Exp Med Biol; 2020; 1217():187-210. PubMed ID: 31898229
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-α protein turnover.
    Zhang P; Gao K; Jin X; Ma J; Peng J; Wumaier R; Tang Y; Zhang Y; An J; Yan Q; Dong Y; Huang H; Yu L; Wang C
    Cell Death Dis; 2015 Mar; 6(3):e1687. PubMed ID: 25766326
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The CUL3-SPOP-DAXX axis is a novel regulator of VEGFR2 expression in vascular endothelial cells.
    Sakaue T; Sakakibara I; Uesugi T; Fujisaki A; Nakashiro KI; Hamakawa H; Kubota E; Joh T; Imai Y; Izutani H; Higashiyama S
    Sci Rep; 2017 Feb; 7():42845. PubMed ID: 28216678
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation.
    Wu F; Dai X; Gan W; Wan L; Li M; Mitsiades N; Wei W; Ding Q; Zhang J
    Cancer Lett; 2017 Jan; 385():207-214. PubMed ID: 27780719
    [TBL] [Abstract][Full Text] [Related]  

  • 13. G3BP1 inhibits Cul3
    Mukhopadhyay C; Yang C; Xu L; Liu D; Wang Y; Huang D; Deonarine LD; Cyrta J; Davicioni E; Sboner A; Robinson BD; Chinnaiyan AM; Rubin MA; Barbieri CE; Zhou P
    Nat Commun; 2021 Nov; 12(1):6662. PubMed ID: 34795264
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis of high-order oligomerization of the cullin-3 adaptor SPOP.
    van Geersdaele LK; Stead MA; Harrison CM; Carr SB; Close HJ; Rosbrook GO; Connell SD; Wright SC
    Acta Crystallogr D Biol Crystallogr; 2013 Sep; 69(Pt 9):1677-84. PubMed ID: 23999291
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase.
    Zhang Q; Shi Q; Chen Y; Yue T; Li S; Wang B; Jiang J
    Proc Natl Acad Sci U S A; 2009 Dec; 106(50):21191-6. PubMed ID: 19955409
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ERK1/2 inhibits Cullin 3/SPOP-mediated PrLZ ubiquitination and degradation to modulate prostate cancer progression.
    Fan Y; Hou T; Dan W; Zhu Y; Liu B; Wei Y; Wang Z; Gao Y; Zeng J; Li L
    Cell Death Differ; 2022 Aug; 29(8):1611-1624. PubMed ID: 35194188
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rotavirus NSP1 Associates with Components of the Cullin RING Ligase Family of E3 Ubiquitin Ligases.
    Lutz LM; Pace CR; Arnold MM
    J Virol; 2016 Jul; 90(13):6036-48. PubMed ID: 27099313
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants.
    Zhang P; Gao K; Tang Y; Jin X; An J; Yu H; Wang H; Zhang Y; Wang D; Huang H; Yu L; Wang C
    Hum Mutat; 2014 Sep; 35(9):1142-51. PubMed ID: 24990631
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SPOP point mutations regulate substrate preference and affect its function.
    Deng Y; Ding W; Ma K; Zhan M; Sun L; Zhou Z; Lu L
    Cell Death Dis; 2024 Feb; 15(2):172. PubMed ID: 38409107
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CRL3-SPOP ubiquitin ligase complex suppresses the growth of diffuse large B-cell lymphoma by negatively regulating the MyD88/NF-κB signaling.
    Jin X; Shi Q; Li Q; Zhou L; Wang J; Jiang L; Zhao X; Feng K; Lin T; Lin Z; Zhuang H; Yang J; Hu C; Zhang L; Shen L; Lu Y; Zhu J; Wang H; Qi H; Meng X; Xi Y; Pan J; Fang S; Tian H; Zhou C; Zhang P; Gao K; Zhao SM; Li Y; Gong Z; Wang C
    Leukemia; 2020 May; 34(5):1305-1314. PubMed ID: 31776466
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.