These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 22087535)

  • 21. Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops.
    Castrignanò S; D'Avino S; Di Nardo G; Catucci G; Sadeghi SJ; Gilardi G
    Biochim Biophys Acta Proteins Proteom; 2018 Jan; 1866(1):116-125. PubMed ID: 28734977
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Prosubstrates of CYP3A4, the major human hepatic cytochrome P450: transformation into substrates by other P450 isoforms.
    Stresser DM; Kupfer D
    Biochem Pharmacol; 1998 Jun; 55(11):1861-71. PubMed ID: 9714305
    [TBL] [Abstract][Full Text] [Related]  

  • 23. N-Dealkylation and hydroxylation of ebastine by human liver cytochrome P450.
    Hashizume T; Mise M; Terauchi Y; O L; Fujii T; Miyazaki H; Inaba T
    Drug Metab Dispos; 1998 Jun; 26(6):566-71. PubMed ID: 9616193
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Influence of P450 3A4 SRS-2 residues on cooperativity and/or regioselectivity of aflatoxin B(1) oxidation.
    Xue L; Wang HF; Wang Q; Szklarz GD; Domanski TL; Halpert JR; Correia MA
    Chem Res Toxicol; 2001 May; 14(5):483-91. PubMed ID: 11368545
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Inhibition of cytochrome P450 3A4 by a pyrimidineimidazole: Evidence for complex heme interactions.
    Hutzler JM; Melton RJ; Rumsey JM; Schnute ME; Locuson CW; Wienkers LC
    Chem Res Toxicol; 2006 Dec; 19(12):1650-9. PubMed ID: 17173379
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Active Site Crowding of Cytochrome P450 3A4 as a Strategy To Alter Its Selectivity.
    Schiavini P; Cheong KJ; Moitessier N; Auclair K
    Chembiochem; 2017 Feb; 18(3):248-252. PubMed ID: 27897366
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Interaction between the substrate and the high-valent-iron-oxo porphyrin cofactor as a possible factor influencing the regioselectivity of cytochrome P450 catalysed aromatic ring hydroxylation of 3-fluoro(methyl)anilines.
    Koerts J; Boeren S; Vervoort J; Weiss R; Veeger C; Rietjens IM
    Chem Biol Interact; 1996 Jan; 99(1-3):129-46. PubMed ID: 8620563
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Characterization of human cytochrome P450 enzymes catalyzing domperidone N-dealkylation and hydroxylation in vitro.
    Ward BA; Morocho A; Kandil A; Galinsky RE; Flockhart DA; Desta Z
    Br J Clin Pharmacol; 2004 Sep; 58(3):277-87. PubMed ID: 15327587
    [TBL] [Abstract][Full Text] [Related]  

  • 29. In vitro assessment of metabolic drug-drug interaction potential of apixaban through cytochrome P450 phenotyping, inhibition, and induction studies.
    Wang L; Zhang D; Raghavan N; Yao M; Ma L; Frost CE; Maxwell BD; Chen SY; He K; Goosen TC; Humphreys WG; Grossman SJ
    Drug Metab Dispos; 2010 Mar; 38(3):448-58. PubMed ID: 19940026
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.
    Bakken GV; Molden E; Knutsen K; Lunder N; Hermann M
    Drug Metab Dispos; 2012 Sep; 40(9):1778-84. PubMed ID: 22688609
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Effects of phenothiazine neuroleptics on the rate of caffeine demethylation and hydroxylation in the rat liver.
    Daniel WA; Syrek M; Ryłko Z; Kot M
    Pol J Pharmacol; 2001; 53(6):615-21. PubMed ID: 11985335
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Regioselective Versatility of Monooxygenase Reactions Catalyzed by CYP2B6 and CYP3A4: Examples with Single Substrates.
    Erratico CA; Deo AK; Bandiera SM
    Adv Exp Med Biol; 2015; 851():131-49. PubMed ID: 26002734
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Activation of human cytochrome P-450 3A4-catalyzed meloxicam 5'-methylhydroxylation by quinidine and hydroquinidine in vitro.
    Ludwig E; Schmid J; Beschke K; Ebner T
    J Pharmacol Exp Ther; 1999 Jul; 290(1):1-8. PubMed ID: 10381752
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Enantiomer/enantiomer interactions between the S- and R- isomers of omeprazole in human cytochrome P450 enzymes: major role of CYP2C19 and CYP3A4.
    Li XQ; Weidolf L; Simonsson R; Andersson TB
    J Pharmacol Exp Ther; 2005 Nov; 315(2):777-87. PubMed ID: 16093273
    [TBL] [Abstract][Full Text] [Related]  

  • 35. RS-predictor: a new tool for predicting sites of cytochrome P450-mediated metabolism applied to CYP 3A4.
    Zaretzki J; Bergeron C; Rydberg P; Huang TW; Bennett KP; Breneman CM
    J Chem Inf Model; 2011 Jul; 51(7):1667-89. PubMed ID: 21528931
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes.
    Hammons GJ; Milton D; Stepps K; Guengerich FP; Tukey RH; Kadlubar FF
    Carcinogenesis; 1997 Apr; 18(4):851-4. PubMed ID: 9111224
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Evidence for cytochrome P450 2A6 and 3A4 as major catalysts for N'-nitrosonornicotine alpha-hydroxylation by human liver microsomes.
    Patten CJ; Smith TJ; Friesen MJ; Tynes RE; Yang CS; Murphy SE
    Carcinogenesis; 1997 Aug; 18(8):1623-30. PubMed ID: 9276639
    [TBL] [Abstract][Full Text] [Related]  

  • 38. 1,2,3-Triazole-heme interactions in cytochrome P450: functionally competent triazole-water-heme complexes.
    Conner KP; Vennam P; Woods CM; Krzyaniak MD; Bowman MK; Atkins WM
    Biochemistry; 2012 Aug; 51(32):6441-57. PubMed ID: 22809252
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Hydroxylation and demethylation of the tricyclic antidepressant nortriptyline by cDNA-expressed human cytochrome P-450 isozymes.
    Olesen OV; Linnet K
    Drug Metab Dispos; 1997 Jun; 25(6):740-4. PubMed ID: 9193876
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).
    He K; Woolf TF; Hollenberg PF
    J Pharmacol Exp Ther; 1999 Feb; 288(2):791-7. PubMed ID: 9918590
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.