BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

299 related articles for article (PubMed ID: 22095588)

  • 1. Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease.
    Bechmann LP; Gastaldelli A; Vetter D; Patman GL; Pascoe L; Hannivoort RA; Lee UE; Fiel I; Muñoz U; Ciociaro D; Lee YM; Buzzigoli E; Miele L; Hui KY; Bugianesi E; Burt AD; Day CP; Mari A; Agius L; Walker M; Friedman SL; Reeves HL
    Hepatology; 2012 Apr; 55(4):1083-93. PubMed ID: 22095588
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis.
    Bechmann LP; Vetter D; Ishida J; Hannivoort RA; Lang UE; Kocabayoglu P; Fiel MI; Muñoz U; Patman GL; Ge F; Yakar S; Li X; Agius L; Lee YM; Zhang W; Hui KY; Televantou D; Schwartz GJ; LeRoith D; Berk PD; Nagai R; Suzuki T; Reeves HL; Friedman SL
    J Hepatol; 2013 May; 58(5):1000-6. PubMed ID: 23353867
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Kruppel-like factor 6 genotype is associated with fibrosis in nonalcoholic fatty liver disease.
    Miele L; Beale G; Patman G; Nobili V; Leathart J; Grieco A; Abate M; Friedman SL; Narla G; Bugianesi E; Day CP; Reeves HL
    Gastroenterology; 2008 Jul; 135(1):282-291.e1. PubMed ID: 18515091
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing.
    Vetter D; Cohen-Naftaly M; Villanueva A; Lee YA; Kocabayoglu P; Hannivoort R; Narla G; M Llovet J; Thung SN; Friedman SL
    Hepatology; 2012 Oct; 56(4):1361-70. PubMed ID: 22535637
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma.
    Yea S; Narla G; Zhao X; Garg R; Tal-Kremer S; Hod E; Villanueva A; Loke J; Tarocchi M; Akita K; Shirasawa S; Sasazuki T; Martignetti JA; Llovet JM; Friedman SL
    Gastroenterology; 2008 May; 134(5):1521-31. PubMed ID: 18471523
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reduced hepatic stellate cell expression of Kruppel-like factor 6 tumor suppressor isoforms amplifies fibrosis during acute and chronic rodent liver injury.
    Ghiassi-Nejad Z; Hernandez-Gea V; Woodrell C; Lang UE; Dumic K; Kwong A; Friedman SL
    Hepatology; 2013 Feb; 57(2):786-96. PubMed ID: 22961688
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hepatic glucokinase expression is associated with lipogenesis and fatty liver in humans.
    Peter A; Stefan N; Cegan A; Walenta M; Wagner S; Königsrainer A; Königsrainer I; Machicao F; Schick F; Häring HU; Schleicher E
    J Clin Endocrinol Metab; 2011 Jul; 96(7):E1126-30. PubMed ID: 21490074
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of miRNAs that specifically target tumor suppressive KLF6-FL rather than oncogenic KLF6-SV1 isoform.
    Liang WC; Wang Y; Xiao LJ; Wang YB; Fu WM; Wang WM; Jiang HQ; Qi W; Wan DC; Zhang JF; Waye MM
    RNA Biol; 2014; 11(7):845-54. PubMed ID: 24921656
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatic Krüppel-like factor 16 (KLF16) targets PPARα to improve steatohepatitis and insulin resistance.
    Sun N; Shen C; Zhang L; Wu X; Yu Y; Yang X; Yang C; Zhong C; Gao Z; Miao W; Yang Z; Gao W; Hu L; Williams K; Liu C; Chang Y; Gao Y
    Gut; 2021 Nov; 70(11):2183-2195. PubMed ID: 33257471
    [TBL] [Abstract][Full Text] [Related]  

  • 10. KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis.
    Narla G; DiFeo A; Fernandez Y; Dhanasekaran S; Huang F; Sangodkar J; Hod E; Leake D; Friedman SL; Hall SJ; Chinnaiyan AM; Gerald WL; Rubin MA; Martignetti JA
    J Clin Invest; 2008 Aug; 118(8):2711-21. PubMed ID: 18596922
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hepatocyte growth factor enhances alternative splicing of the Kruppel-like factor 6 (KLF6) tumor suppressor to promote growth through SRSF1.
    Muñoz Ú; Puche JE; Hannivoort R; Lang UE; Cohen-Naftaly M; Friedman SL
    Mol Cancer Res; 2012 Sep; 10(9):1216-27. PubMed ID: 22859706
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma.
    Narla G; Kremer-Tal S; Matsumoto N; Zhao X; Yao S; Kelley K; Tarocchi M; Friedman SL
    Oncogene; 2007 Jun; 26(30):4428-34. PubMed ID: 17297474
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeted reduction of KLF6-SV1 restores chemotherapy sensitivity in resistant lung adenocarcinoma.
    Sangodkar J; DiFeo A; Feld L; Bromberg R; Schwartz R; Huang F; Terzo EA; Choudhri A; Narla G
    Lung Cancer; 2009 Dec; 66(3):292-7. PubMed ID: 19328586
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic inactivation of the LIGHT (TNFSF14) cytokine in mice restores glucose homeostasis and diminishes hepatic steatosis.
    Herrero-Cervera A; Vinué Á; Burks DJ; González-Navarro H
    Diabetologia; 2019 Nov; 62(11):2143-2157. PubMed ID: 31388695
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury.
    Sydor S; Manka P; Best J; Jafoui S; Sowa JP; Zoubek ME; Hernandez-Gea V; Cubero FJ; Kälsch J; Vetter D; Fiel MI; Hoshida Y; Bian CB; Nelson LJ; Moshage H; Faber KN; Paul A; Baba HA; Gerken G; Friedman SL; Canbay A; Bechmann LP
    Sci Rep; 2017 Aug; 7(1):8119. PubMed ID: 28808340
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Vascular injury triggers Krüppel-like factor 6 mobilization and cooperation with specificity protein 1 to promote endothelial activation through upregulation of the activin receptor-like kinase 1 gene.
    Garrido-Martín EM; Blanco FJ; Roquè M; Novensà L; Tarocchi M; Lang UE; Suzuki T; Friedman SL; Botella LM; Bernabéu C
    Circ Res; 2013 Jan; 112(1):113-27. PubMed ID: 23048070
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Direct and systemic actions of growth hormone receptor (GHR)-signaling on hepatic glycolysis, de novo lipogenesis and insulin sensitivity, associated with steatosis.
    Vázquez-Borrego MC; Del Río-Moreno M; Pyatkov M; Sarmento-Cabral A; Mahmood M; Pelke N; Wnek M; Cordoba-Chacon J; Waxman DJ; Puchowicz MA; McGuinness OP; Kineman RD
    Metabolism; 2023 Jul; 144():155589. PubMed ID: 37182789
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A small interfering RNA targeting the KLF6 splice variant, KLF6-SV1, as gene therapy for gastric cancer.
    Chen H; Chen L; Sun L; Zhen H; Li X; Zhang Q
    Gastric Cancer; 2011 Oct; 14(4):339-52. PubMed ID: 21538018
    [TBL] [Abstract][Full Text] [Related]  

  • 19. KLF6-SV1 drives breast cancer metastasis and is associated with poor survival.
    Hatami R; Sieuwerts AM; Izadmehr S; Yao Z; Qiao RF; Papa L; Look MP; Smid M; Ohlssen J; Levine AC; Germain D; Burstein D; Kirschenbaum A; DiFeo A; Foekens JA; Narla G
    Sci Transl Med; 2013 Jan; 5(169):169ra12. PubMed ID: 23345610
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of KLF6 and its splice variants in cancer therapy.
    DiFeo A; Martignetti JA; Narla G
    Drug Resist Updat; 2009; 12(1-2):1-7. PubMed ID: 19097929
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.