These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 22107946)

  • 1. A-ring analogs of 1,25-dihydroxyvitamin D(3).
    Glebocka A; Chiellini G
    Arch Biochem Biophys; 2012 Jul; 523(1):48-57. PubMed ID: 22107946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 1alpha,25-dihydroxy-16-ene-23-yne-vitamin D3 and 1alpha,25-dihydroxy-16-ene-23-yne-20-epi-vitamin D3: analogs of 1alpha,25-dihydroxyvitamin D3 that resist metabolism through the C-24 oxidation pathway are metabolized through the C-3 epimerization pathway.
    Reddy GS; Rao DS; Siu-Caldera ML; Astecker N; Weiskopf A; Vouros P; Sasso GJ; Manchand PS; Uskokovic MR
    Arch Biochem Biophys; 2000 Nov; 383(2):197-205. PubMed ID: 11185554
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Removal of C-ring from the CD-ring skeleton of 1alpha,25-dihydroxyvitamin D3 does not alter its target tissue metabolism significantly.
    Reddy GS; Robinson M; Wang G; Palmore GT; Gennaro L; Vouros P; De Clercq P; Vandewalle M; Young W; Ling S; Verstuyf A; Bouillon R
    Arch Biochem Biophys; 2007 Apr; 460(2):254-61. PubMed ID: 17196157
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological activities of new 1alpha,25-dihydroxy-19-norvitamin D3 analogs with modifications in both the A-ring and the side chain.
    Shimizu M; Miyamoto Y; Kobayashi E; Shimazaki M; Yamamoto K; Reischl W; Yamada S
    Bioorg Med Chem; 2006 Jun; 14(12):4277-94. PubMed ID: 16503143
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biological activity of CD-ring modified 1alpha,25-dihydroxyvitamin D analogues: C-ring and five-membered D-ring analogues.
    Verstuyf A; Verlinden L; van Etten E; Shi L; Wu Y; D'Halleweyn C; Van Haver D; Zhu GD; Chen YJ; Zhou X; Haussler MR; De Clercq P; Vandewalle M; Van Baelen H; Mathieu C; Bouillon R
    J Bone Miner Res; 2000 Feb; 15(2):237-52. PubMed ID: 10703925
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues.
    Demin S; Van Haver D; Vandewalle M; De Clercq PJ; Bouillon R; Verstuyf A
    Bioorg Med Chem Lett; 2004 Aug; 14(15):3885-8. PubMed ID: 15225690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New 1alpha,25-dihydroxy-19-norvitamin D3 compounds of high biological activity: synthesis and biological evaluation of 2-hydroxymethyl, 2-methyl, and 2-methylene analogues.
    Sicinski RR; Prahl JM; Smith CM; DeLuca HF
    J Med Chem; 1998 Nov; 41(23):4662-74. PubMed ID: 9804706
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 13-Methyl-substituted des-C,D analogs of (20S)-1alpha,25-dihydroxy-2-methylene-19-norvitamin D3 (2MD): synthesis and biological evaluation.
    Plonska-Ocypa K; Sicinski RR; Plum LA; Grzywacz P; Frelek J; Clagett-Dame M; DeLuca HF
    Bioorg Med Chem; 2009 Feb; 17(4):1747-63. PubMed ID: 19167893
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Highly active analogs of 1alpha,25-dihydroxyvitamin D(3) that resist metabolism through C-24 oxidation and C-3 epimerization pathways.
    Uskokovic MR; Norman AW; Manchand PS; Studzinski GP; Campbell MJ; Koeffler HP; Takeuchi A; Siu-Caldera ML; Rao DS; Reddy GS
    Steroids; 2001; 66(3-5):463-71. PubMed ID: 11179755
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Methyl substitution of the 25-hydroxy group on 2-methylene-19-nor-1alpha,25-dihydroxyvitamin D3 (2MD) reduces potency but allows bone selectivity.
    Grzywacz P; Plum LA; Sicinski RR; Clagett-Dame M; DeLuca HF
    Arch Biochem Biophys; 2007 Apr; 460(2):274-84. PubMed ID: 17094936
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: spiro[5.5]undecane CF-ring analogues.
    Schepens W; Van Haver DV; Vandewalle M; De Clercq PJ; Bouillon R; Verstuyf A
    Bioorg Med Chem Lett; 2004 Aug; 14(15):3889-92. PubMed ID: 15225691
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The biological activity of nonsteroidal vitamin D hormone analogs lacking both the C- and D-rings.
    Verstuyf A; Verlinden L; Van Baelen H; Sabbe K; D'Hallewyn C; De Clercq P; Vandewalle M; Bouillon R
    J Bone Miner Res; 1998 Apr; 13(4):549-58. PubMed ID: 9556055
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Highly potent 2-methylene analogs of 1α,25-dihydroxyvitamin D3: synthesis and biological evaluation.
    Sibilska IK; Szybinski M; Sicinski RR; Plum LA; Deluca HF
    J Steroid Biochem Mol Biol; 2013 Jul; 136():9-13. PubMed ID: 23410597
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 13,13-Dimethyl-des-C,D analogues of (20S)-1α,25-dihydroxy-2-methylene-19-norvitamin D₃ (2MD): total synthesis, docking to the VDR, and biological evaluation.
    Plonska-Ocypa K; Sibilska I; Sicinski RR; Sicinska W; Plum LA; DeLuca HF
    Bioorg Med Chem; 2011 Dec; 19(23):7205-20. PubMed ID: 22018918
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 2-Methylene analogs of 1alpha-hydroxy-19-norvitamin D3: synthesis, biological activities and docking to the ligand binding domain of the rat vitamin D receptor.
    Grzywacz P; Plum LA; Sicinska W; Sicinski RR; Prahl JM; DeLuca HF
    J Steroid Biochem Mol Biol; 2004 May; 89-90(1-5):13-7. PubMed ID: 15225739
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Asymmetric catalytic ene-cyclization approach to 2-fluoro-19-nor-1,25-dihydroxyvitamin D(3) A-ring analog with significant transactivation activity.
    Mikami K; Ohba S; Ohmura H; Kubodera N; Nakagawa K; Okano T
    Chirality; 2001 Jul; 13(7):366-71. PubMed ID: 11400190
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Conformation-function relationship of vitamin D: conformational analysis predicts potential side-chain structure.
    Yamada S; Yamamoto K; Masuno H; Ohta M
    J Med Chem; 1998 Apr; 41(9):1467-75. PubMed ID: 9554880
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The development of CD-ring modified analogs of 1alpha,25-dihydroxyvitamin D.
    De Clercq PJ; De Buysser F; Minne G; Schepens W; Vrielynck F; Van Haver D; Vandewalle M; Verstuyf A; Bouillon R
    J Steroid Biochem Mol Biol; 2007 Mar; 103(3-5):206-12. PubMed ID: 17218098
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Low-calcemic, highly antiproliferative, 1-difluoromethyl hybrid analogs of the natural hormone 1alpha,25-dihydroxyvitamin D3: design, synthesis, and preliminary biological evaluation.
    Peleg S; Petersen KS; Suh BC; Dolan P; Agoston ES; Kensler TW; Posner GH
    J Med Chem; 2006 Dec; 49(25):7513-7. PubMed ID: 17149880
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A-ring hydroxymethyl 19-nor analogs of the natural hormone 1alpha,25-dihydroxyvitamin D(3): synthesis and preliminary biological evaluation.
    Hatcher MA; Peleg S; Dolan P; Kensler TW; Sarjeant A; Posner GH
    Bioorg Med Chem; 2005 Jun; 13(12):3964-76. PubMed ID: 15878279
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.