121 related articles for article (PubMed ID: 22108178)
1. Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites.
Mürdter TE; Kerb R; Turpeinen M; Schroth W; Ganchev B; Böhmer GM; Igel S; Schaeffeler E; Zanger U; Brauch H; Schwab M
Hum Mol Genet; 2012 Mar; 21(5):1145-54. PubMed ID: 22108178
[TBL] [Abstract][Full Text] [Related]
2. CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver.
Dehal SS; Kupfer D
Cancer Res; 1997 Aug; 57(16):3402-6. PubMed ID: 9270005
[TBL] [Abstract][Full Text] [Related]
3. Metabolism of clomiphene in the rat. Estrogen receptor affinity and antiestrogenic activity of clomiphene metabolites.
Ruenitz PC; Bagley JR; Mokler CM
Biochem Pharmacol; 1983 Oct; 32(19):2941-7. PubMed ID: 6626264
[TBL] [Abstract][Full Text] [Related]
4. Genetic Polymorphism of CYP2D6 and Clomiphene Concentrations in Infertile Patients with Ovulatory Dysfunction Treated with Clomiphene Citrate.
Ji M; Kim KR; Lee W; Choe W; Chun S; Min WK
J Korean Med Sci; 2016 Feb; 31(2):310-4. PubMed ID: 26839488
[TBL] [Abstract][Full Text] [Related]
5. Effect of the CYP2D6*10 allele on the pharmacokinetics of clomiphene and its active metabolites.
Kim MJ; Byeon JY; Kim YH; Kim SH; Lee CM; Jung EH; Chae WK; Lee YJ; Jang CG; Lee SY; Choi CI
Arch Pharm Res; 2018 Mar; 41(3):347-353. PubMed ID: 29516347
[TBL] [Abstract][Full Text] [Related]
6. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
[TBL] [Abstract][Full Text] [Related]
7. Interaction of terfenadine and its primary metabolites with cytochrome P450 2D6.
Jones BC; Hyland R; Ackland M; Tyman CA; Smith DA
Drug Metab Dispos; 1998 Sep; 26(9):875-82. PubMed ID: 9733666
[TBL] [Abstract][Full Text] [Related]
8. Genetic polymorphism in cytochrome P450 2D6 (CYP2D6): Population distribution of CYP2D6 activity.
Neafsey P; Ginsberg G; Hattis D; Sonawane B
J Toxicol Environ Health B Crit Rev; 2009; 12(5-6):334-61. PubMed ID: 20183526
[TBL] [Abstract][Full Text] [Related]
9. Influence of Val16Ala SOD2 polymorphism on the in-vitro effect of clomiphene citrate in oxidative metabolism.
Costa F; Dornelles E; Mânica-Cattani MF; Algarve TD; Souza Filho OC; Sagrillo MR; Garcia LF; Cruz IB
Reprod Biomed Online; 2012 Apr; 24(4):474-81. PubMed ID: 22386763
[TBL] [Abstract][Full Text] [Related]
10. Clinical significance of CYP2D6 polymorphisms and tamoxifen in women with breast cancer.
Gaston C; Kolesar J
Clin Adv Hematol Oncol; 2008 Nov; 6(11):825-33. PubMed ID: 19194367
[TBL] [Abstract][Full Text] [Related]
11. Substrate specific metabolism by polymorphic cytochrome P450 2D6 alleles.
Bogni A; Monshouwer M; Moscone A; Hidestrand M; Ingelman-Sundberg M; Hartung T; Coecke S
Toxicol In Vitro; 2005 Aug; 19(5):621-9. PubMed ID: 15893449
[TBL] [Abstract][Full Text] [Related]
12. Targeting of tamoxifen to enhance antitumour action for the treatment and prevention of breast cancer: the 'personalised' approach?
Brauch H; Jordan VC
Eur J Cancer; 2009 Sep; 45(13):2274-83. PubMed ID: 19592233
[TBL] [Abstract][Full Text] [Related]
13. Recombinant production of human microsomal cytochrome P450 2D6 in the methylotrophic yeast Pichia pastoris.
Dietrich M; Grundmann L; Kurr K; Valinotto L; Saussele T; Schmid RD; Lange S
Chembiochem; 2005 Nov; 6(11):2014-22. PubMed ID: 16222729
[TBL] [Abstract][Full Text] [Related]
14. The antipsychotic clozapine is metabolized by the polymorphic human microsomal and recombinant cytochrome P450 2D6.
Fischer V; Vogels B; Maurer G; Tynes RE
J Pharmacol Exp Ther; 1992 Mar; 260(3):1355-60. PubMed ID: 1545398
[TBL] [Abstract][Full Text] [Related]
15. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
[TBL] [Abstract][Full Text] [Related]
16. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
[TBL] [Abstract][Full Text] [Related]
17. Identification of human cytochrome P450 2D6 as major enzyme involved in the O-demethylation of the designer drug p-methoxymethamphetamine.
Staack RF; Theobald DS; Paul LD; Springer D; Kraemer T; Maurer HH
Drug Metab Dispos; 2004 Apr; 32(4):379-81. PubMed ID: 15039289
[TBL] [Abstract][Full Text] [Related]
18. Characterization of the biotransformation pathways of clomiphene, tamoxifen and toremifene as assessed by LC-MS/(MS) following in vitro and excretion studies.
Mazzarino M; Biava M; de la Torre X; Fiacco I; Botrè F
Anal Bioanal Chem; 2013 Jun; 405(16):5467-87. PubMed ID: 23604525
[TBL] [Abstract][Full Text] [Related]
19. Tamoxifen, cytochrome P450 genes and breast cancer clinical outcomes.
Singh MS; Francis PA; Michael M
Breast; 2011 Apr; 20(2):111-8. PubMed ID: 21185724
[TBL] [Abstract][Full Text] [Related]
20. Effects of monoamine oxidase inhibitor and cytochrome P450 2D6 status on 5-methoxy-N,N-dimethyltryptamine metabolism and pharmacokinetics.
Shen HW; Wu C; Jiang XL; Yu AM
Biochem Pharmacol; 2010 Jul; 80(1):122-8. PubMed ID: 20206139
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]