183 related articles for article (PubMed ID: 22110726)
1. The identification of a small molecule compound that reduces HIV-1 Nef-mediated viral infectivity enhancement.
Chutiwitoonchai N; Hiyoshi M; Mwimanzi P; Ueno T; Adachi A; Ode H; Sato H; Fackler OT; Okada S; Suzu S
PLoS One; 2011; 6(11):e27696. PubMed ID: 22110726
[TBL] [Abstract][Full Text] [Related]
2. Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.
Alvarado JJ; Tarafdar S; Yeh JI; Smithgall TE
J Biol Chem; 2014 Oct; 289(41):28539-53. PubMed ID: 25122770
[TBL] [Abstract][Full Text] [Related]
3. HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon.
Cornall A; Mak J; Greenway A; Tachedjian G
Viruses; 2013 Sep; 5(9):2235-52. PubMed ID: 24051604
[TBL] [Abstract][Full Text] [Related]
4. The cellular kinase binding motifs (PxxP and RR) in human immunodeficiency virus type 1 Nef protein are dispensable for producer-cell-dependent enhancement of viral entry.
Tokunaga K; Ikuta K; Adachi A; Matsuda M; Kurata T; Kojima A
Virology; 1999 May; 257(2):285-9. PubMed ID: 10329538
[TBL] [Abstract][Full Text] [Related]
5. Structure, dynamics, and Hck interaction of full-length HIV-1 Nef.
Jung J; Byeon IJ; Ahn J; Gronenborn AM
Proteins; 2011 May; 79(5):1609-22. PubMed ID: 21365684
[TBL] [Abstract][Full Text] [Related]
6. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein.
Lee CH; Leung B; Lemmon MA; Zheng J; Cowburn D; Kuriyan J; Saksela K
EMBO J; 1995 Oct; 14(20):5006-15. PubMed ID: 7588629
[TBL] [Abstract][Full Text] [Related]
7. The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.
Dutartre H; Harris M; Olive D; Collette Y
Virology; 1998 Aug; 247(2):200-11. PubMed ID: 9705913
[TBL] [Abstract][Full Text] [Related]
8. Subtle Dynamic Changes Accompany Hck Activation by HIV-1 Nef and are Reversed by an Antiretroviral Kinase Inhibitor.
Wales TE; Hochrein JM; Morgan CR; Emert-Sedlak LA; Smithgall TE; Engen JR
Biochemistry; 2015 Oct; 54(41):6382-91. PubMed ID: 26440750
[TBL] [Abstract][Full Text] [Related]
9. Overlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix.
Kuo LS; Baugh LL; Denial SJ; Watkins RL; Liu M; Garcia JV; Foster JL
Retrovirology; 2012 May; 9():47. PubMed ID: 22651890
[TBL] [Abstract][Full Text] [Related]
10. Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4.
Saksela K; Cheng G; Baltimore D
EMBO J; 1995 Feb; 14(3):484-91. PubMed ID: 7859737
[TBL] [Abstract][Full Text] [Related]
11. Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function.
Meuwissen PJ; Stolp B; Iannucci V; Vermeire J; Naessens E; Saksela K; Geyer M; Vanham G; Arien KK; Fackler OT; Verhasselt B
Retrovirology; 2012 Apr; 9():34. PubMed ID: 22537596
[TBL] [Abstract][Full Text] [Related]
12. Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions.
Bouchet J; Hérate C; Guenzel CA; Vérollet C; Järviluoma A; Mazzolini J; Rafie S; Chames P; Baty D; Saksela K; Niedergang F; Maridonneau-Parini I; Benichou S
J Virol; 2012 May; 86(9):4856-67. PubMed ID: 22345475
[TBL] [Abstract][Full Text] [Related]
13. SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.
Briggs SD; Sharkey M; Stevenson M; Smithgall TE
J Biol Chem; 1997 Jul; 272(29):17899-902. PubMed ID: 9218412
[TBL] [Abstract][Full Text] [Related]
14. Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation.
Greenway AL; Dutartre H; Allen K; McPhee DA; Olive D; Collette Y
J Virol; 1999 Jul; 73(7):6152-8. PubMed ID: 10364375
[TBL] [Abstract][Full Text] [Related]
15. Chemical library screens targeting an HIV-1 accessory factor/host cell kinase complex identify novel antiretroviral compounds.
Emert-Sedlak L; Kodama T; Lerner EC; Dai W; Foster C; Day BW; Lazo JS; Smithgall TE
ACS Chem Biol; 2009 Nov; 4(11):939-47. PubMed ID: 19807124
[TBL] [Abstract][Full Text] [Related]
16. Conserved residues in the HIV-1 Nef hydrophobic pocket are essential for recruitment and activation of the Hck tyrosine kinase.
Choi HJ; Smithgall TE
J Mol Biol; 2004 Nov; 343(5):1255-68. PubMed ID: 15491611
[TBL] [Abstract][Full Text] [Related]
17. Competitive displacement of full-length HIV-1 Nef from the Hck SH3 domain by a high-affinity artificial peptide.
Stangler T; Tran T; Hoffmann S; Schmidt H; Jonas E; Willbold D
Biol Chem; 2007 Jun; 388(6):611-5. PubMed ID: 17552908
[TBL] [Abstract][Full Text] [Related]
18. Nef alleles from all major HIV-1 clades activate Src-family kinases and enhance HIV-1 replication in an inhibitor-sensitive manner.
Narute PS; Smithgall TE
PLoS One; 2012; 7(2):e32561. PubMed ID: 22393415
[TBL] [Abstract][Full Text] [Related]
19. Nef proteins of distinct HIV-1 or -2 isolates differ in their binding properties for HCK: isolation of a novel Nef binding factor with characteristics of an adaptor protein.
Karn T; Hock B; Holtrich U; Adamski M; Strebhardt K; Rübsamen-Waigmann H
Virology; 1998 Jun; 246(1):45-52. PubMed ID: 9656992
[TBL] [Abstract][Full Text] [Related]
20. RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.
Arold S; O'Brien R; Franken P; Strub MP; Hoh F; Dumas C; Ladbury JE
Biochemistry; 1998 Oct; 37(42):14683-91. PubMed ID: 9778343
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]