208 related articles for article (PubMed ID: 22112806)
21. Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor.
Neumann S; Krause G; Claus M; Paschke R
Endocrinology; 2005 Jan; 146(1):477-85. PubMed ID: 15498884
[TBL] [Abstract][Full Text] [Related]
22. The middle portion in the second cytoplasmic loop of the thyrotropin receptor plays a crucial role in adenylate cyclase activation.
Kosugi S; Kohn LD; Akamizu T; Mori T
Mol Endocrinol; 1994 Apr; 8(4):498-509. PubMed ID: 7914349
[TBL] [Abstract][Full Text] [Related]
23. High constitutive activity of a virus-encoded seven transmembrane receptor in the absence of the conserved DRY motif (Asp-Arg-Tyr) in transmembrane helix 3.
Rosenkilde MM; Kledal TN; Schwartz TW
Mol Pharmacol; 2005 Jul; 68(1):11-9. PubMed ID: 15788740
[TBL] [Abstract][Full Text] [Related]
24. Congenital hypothyroidism with impaired thyroid response to thyrotropin (TSH) and absent circulating thyroglobulin: evidence for a new inactivating mutation of the TSH receptor gene.
Tonacchera M; Agretti P; Pinchera A; Rosellini V; Perri A; Collecchi P; Vitti P; Chiovato L
J Clin Endocrinol Metab; 2000 Mar; 85(3):1001-8. PubMed ID: 10720030
[TBL] [Abstract][Full Text] [Related]
25. Constitutive activation of the thyrotropin receptor by deletion of a portion of the extracellular domain.
Zhang ML; Sugawa H; Kosugi S; Mori T
Biochem Biophys Res Commun; 1995 Jun; 211(1):205-10. PubMed ID: 7779086
[TBL] [Abstract][Full Text] [Related]
26. A familial thyrotropin (TSH) receptor mutation provides in vivo evidence that the inositol phosphates/Ca2+ cascade mediates TSH action on thyroid hormone synthesis.
Grasberger H; Van Sande J; Hag-Dahood Mahameed A; Tenenbaum-Rakover Y; Refetoff S
J Clin Endocrinol Metab; 2007 Jul; 92(7):2816-20. PubMed ID: 17456567
[TBL] [Abstract][Full Text] [Related]
27. Current standards, variations, and pitfalls for the determination of constitutive TSHR activity in vitro.
Mueller S; Jaeschke H; Paschke R
Methods Enzymol; 2010; 485():421-36. PubMed ID: 21050930
[TBL] [Abstract][Full Text] [Related]
28. The Pathogenic TSH β-subunit Variant C105Vfs114X Causes a Modified Signaling Profile at TSHR.
Kalveram L; Kleinau G; Szymańska K; Scheerer P; Rivero-Müller A; Grüters-Kieslich A; Biebermann H
Int J Mol Sci; 2019 Nov; 20(22):. PubMed ID: 31703413
[TBL] [Abstract][Full Text] [Related]
29. Thyrotropin-stimulating hormone receptor gene analysis in pediatric patients with non-autoimmune subclinical hypothyroidism.
Nicoletti A; Bal M; De Marco G; Baldazzi L; Agretti P; Menabò S; Ballarini E; Cicognani A; Tonacchera M; Cassio A
J Clin Endocrinol Metab; 2009 Nov; 94(11):4187-94. PubMed ID: 19820021
[TBL] [Abstract][Full Text] [Related]
30. The hinge region of the TSH receptor stabilizes ligand binding and determines different signaling profiles of human and bovine TSH.
Jaeschke H; Schaarschmidt J; Günther R; Mueller S
Endocrinology; 2011 Oct; 152(10):3986-96. PubMed ID: 21846801
[TBL] [Abstract][Full Text] [Related]
31. Mutations of the human thyrotropin receptor gene causing thyroid hypoplasia and persistent congenital hypothyroidism.
Biebermann H; Schöneberg T; Krude H; Schultz G; Gudermann T; Grüters A
J Clin Endocrinol Metab; 1997 Oct; 82(10):3471-80. PubMed ID: 9329388
[TBL] [Abstract][Full Text] [Related]
32. Effects of mutations involving cysteine residues distal to the S281HCC motif at the C-terminus on the functional characteristics of a truncated ectodomain-only thyrotropin receptor anchored on glycosylphosphatidyl-inositol.
Ho SC; Goh SS; Li S; Khoo DH; Paterson M
Thyroid; 2008 Dec; 18(12):1313-9. PubMed ID: 18976165
[TBL] [Abstract][Full Text] [Related]
33. Controversial constitutive TSHR activity: patients, physiology, and in vitro characterization.
Huth S; Jaeschke H; Schaarschmidt J; Paschke R
Horm Metab Res; 2014 Jun; 46(7):453-61. PubMed ID: 24845969
[TBL] [Abstract][Full Text] [Related]
34. The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding.
Gu WX; Du GG; Kopp P; Rentoumis A; Albanese C; Kohn LD; Madison LD; Jameson JL
Endocrinology; 1995 Jul; 136(7):3146-53. PubMed ID: 7789342
[TBL] [Abstract][Full Text] [Related]
35. Defining structural and functional dimensions of the extracellular thyrotropin receptor region.
Kleinau G; Mueller S; Jaeschke H; Grzesik P; Neumann S; Diehl A; Paschke R; Krause G
J Biol Chem; 2011 Jun; 286(25):22622-31. PubMed ID: 21525003
[TBL] [Abstract][Full Text] [Related]
36. Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades.
Parma J; Van Sande J; Swillens S; Tonacchera M; Dumont J; Vassart G
Mol Endocrinol; 1995 Jun; 9(6):725-33. PubMed ID: 8592518
[TBL] [Abstract][Full Text] [Related]
37. Thyrotropin receptor mutations as a tool to understand thyrotropin receptor action.
Wonerow P; Neumann S; Gudermann T; Paschke R
J Mol Med (Berl); 2001 Dec; 79(12):707-21. PubMed ID: 11862314
[TBL] [Abstract][Full Text] [Related]
38. Suppression of thyrotropin receptor constitutive activity by a monoclonal antibody with inverse agonist activity.
Chen CR; McLachlan SM; Rapoport B
Endocrinology; 2007 May; 148(5):2375-82. PubMed ID: 17272389
[TBL] [Abstract][Full Text] [Related]
39. Functional characterization of five constitutively activating thyrotrophin receptor mutations.
Wonerow P; Chey S; Führer D; Holzapfel HP; Paschke R
Clin Endocrinol (Oxf); 2000 Oct; 53(4):461-8. PubMed ID: 11012571
[TBL] [Abstract][Full Text] [Related]
40. Low prevalence of thyrotropin receptor mutations in a large series of subjects with sporadic and familial nonautoimmune subclinical hypothyroidism.
Tonacchera M; Perri A; De Marco G; Agretti P; Banco ME; Di Cosmo C; Grasso L; Vitti P; Chiovato L; Pinchera A
J Clin Endocrinol Metab; 2004 Nov; 89(11):5787-93. PubMed ID: 15531543
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
