These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

622 related articles for article (PubMed ID: 22113615)

  • 1. Mutations causing syndromic autism define an axis of synaptic pathophysiology.
    Auerbach BD; Osterweil EK; Bear MF
    Nature; 2011 Nov; 480(7375):63-8. PubMed ID: 22113615
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
    Ronesi JA; Collins KA; Hays SA; Tsai NP; Guo W; Birnbaum SG; Hu JH; Worley PF; Gibson JR; Huber KM
    Nat Neurosci; 2012 Jan; 15(3):431-40, S1. PubMed ID: 22267161
    [TBL] [Abstract][Full Text] [Related]  

  • 3. β-Arrestin2 Couples Metabotropic Glutamate Receptor 5 to Neuronal Protein Synthesis and Is a Potential Target to Treat Fragile X.
    Stoppel LJ; Auerbach BD; Senter RK; Preza AR; Lefkowitz RJ; Bear MF
    Cell Rep; 2017 Mar; 18(12):2807-2814. PubMed ID: 28329674
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome.
    Suvrathan A; Hoeffer CA; Wong H; Klann E; Chattarji S
    Proc Natl Acad Sci U S A; 2010 Jun; 107(25):11591-6. PubMed ID: 20534533
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex.
    Chévere-Torres I; Kaphzan H; Bhattacharya A; Kang A; Maki JM; Gambello MJ; Arbiser JL; Santini E; Klann E
    Neurobiol Dis; 2012 Mar; 45(3):1101-10. PubMed ID: 22198573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of the fragile X mental retardation protein decouples metabotropic glutamate receptor dependent priming of long-term potentiation from protein synthesis.
    Auerbach BD; Bear MF
    J Neurophysiol; 2010 Aug; 104(2):1047-51. PubMed ID: 20554840
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.
    Ehninger D; Han S; Shilyansky C; Zhou Y; Li W; Kwiatkowski DJ; Ramesh V; Silva AJ
    Nat Med; 2008 Aug; 14(8):843-8. PubMed ID: 18568033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism.
    Baudouin SJ; Gaudias J; Gerharz S; Hatstatt L; Zhou K; Punnakkal P; Tanaka KF; Spooren W; Hen R; De Zeeuw CI; Vogt K; Scheiffele P
    Science; 2012 Oct; 338(6103):128-32. PubMed ID: 22983708
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Toward fulfilling the promise of molecular medicine in fragile X syndrome.
    Krueger DD; Bear MF
    Annu Rev Med; 2011; 62():411-29. PubMed ID: 21090964
    [TBL] [Abstract][Full Text] [Related]  

  • 10. R-Baclofen Reverses a Social Behavior Deficit and Elevated Protein Synthesis in a Mouse Model of Fragile X Syndrome.
    Qin M; Huang T; Kader M; Krych L; Xia Z; Burlin T; Zeidler Z; Zhao T; Smith CB
    Int J Neuropsychopharmacol; 2015 Mar; 18(9):. PubMed ID: 25820841
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hypersensitivity to mGluR5 and ERK1/2 leads to excessive protein synthesis in the hippocampus of a mouse model of fragile X syndrome.
    Osterweil EK; Krueger DD; Reinhold K; Bear MF
    J Neurosci; 2010 Nov; 30(46):15616-27. PubMed ID: 21084617
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome.
    Nosyreva ED; Huber KM
    J Neurophysiol; 2006 May; 95(5):3291-5. PubMed ID: 16452252
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors.
    Nakamoto M; Nalavadi V; Epstein MP; Narayanan U; Bassell GJ; Warren ST
    Proc Natl Acad Sci U S A; 2007 Sep; 104(39):15537-42. PubMed ID: 17881561
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice.
    Aloisi E; Le Corf K; Dupuis J; Zhang P; Ginger M; Labrousse V; Spatuzza M; Georg Haberl M; Costa L; Shigemoto R; Tappe-Theodor A; Drago F; Vincenzo Piazza P; Mulle C; Groc L; Ciranna L; Catania MV; Frick A
    Nat Commun; 2017 Oct; 8(1):1103. PubMed ID: 29062097
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence for a fragile X mental retardation protein-mediated translational switch in metabotropic glutamate receptor-triggered Arc translation and long-term depression.
    Niere F; Wilkerson JR; Huber KM
    J Neurosci; 2012 Apr; 32(17):5924-36. PubMed ID: 22539853
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.
    Takeuchi K; Gertner MJ; Zhou J; Parada LF; Bennett MV; Zukin RS
    Proc Natl Acad Sci U S A; 2013 Mar; 110(12):4738-43. PubMed ID: 23487788
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism.
    D'Antoni S; Spatuzza M; Bonaccorso CM; Musumeci SA; Ciranna L; Nicoletti F; Huber KM; Catania MV
    Neurosci Biobehav Rev; 2014 Oct; 46 Pt 2(Pt 2):228-41. PubMed ID: 24548786
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome.
    Boda B; Mendez P; Boury-Jamot B; Magara F; Muller D
    Eur J Neurosci; 2014 Apr; 39(7):1130-7. PubMed ID: 24712992
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion.
    Tian D; Stoppel LJ; Heynen AJ; Lindemann L; Jaeschke G; Mills AA; Bear MF
    Nat Neurosci; 2015 Feb; 18(2):182-4. PubMed ID: 25581360
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
    Tsai PT; Hull C; Chu Y; Greene-Colozzi E; Sadowski AR; Leech JM; Steinberg J; Crawley JN; Regehr WG; Sahin M
    Nature; 2012 Aug; 488(7413):647-51. PubMed ID: 22763451
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.