These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 22114915)

  • 1. Toward in vitro biomarkers for developmental toxicity and their extrapolation to the in vivo situation.
    Louisse J; Verwei M; Woutersen RA; Blaauboer BJ; Rietjens IM
    Expert Opin Drug Metab Toxicol; 2012 Jan; 8(1):11-27. PubMed ID: 22114915
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose-response curves for developmental toxicity of phenol in rat and human.
    Strikwold M; Spenkelink B; Woutersen RA; Rietjens IM; Punt A
    Arch Toxicol; 2013 Sep; 87(9):1709-23. PubMed ID: 23943240
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling.
    Louisse J; Bosgra S; Blaauboer BJ; Rietjens IM; Verwei M
    Arch Toxicol; 2015 Jul; 89(7):1135-48. PubMed ID: 24935252
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols.
    Strikwold M; Spenkelink B; de Haan LHJ; Woutersen RA; Punt A; Rietjens IMCM
    Arch Toxicol; 2017 May; 91(5):2119-2133. PubMed ID: 27815601
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Use of physiologically based kinetic modeling-facilitated reverse dosimetry of in vitro toxicity data for prediction of in vivo developmental toxicity of tebuconazole in rats.
    Li H; Zhang M; Vervoort J; Rietjens IM; van Ravenzwaay B; Louisse J
    Toxicol Lett; 2017 Jan; 266():85-93. PubMed ID: 27890808
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Establishment and assessment of a new human embryonic stem cell-based biomarker assay for developmental toxicity screening.
    Palmer JA; Smith AM; Egnash LA; Conard KR; West PR; Burrier RE; Donley EL; Kirchner FR
    Birth Defects Res B Dev Reprod Toxicol; 2013 Aug; 98(4):343-63. PubMed ID: 24123775
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: The case of kidney toxicity induced by aristolochic acid I.
    Abdullah R; Alhusainy W; Woutersen J; Rietjens IM; Punt A
    Food Chem Toxicol; 2016 Jun; 92():104-16. PubMed ID: 27016491
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Relative developmental toxicity potencies of retinoids in the embryonic stem cell test compared with their relative potencies in in vivo and two other in vitro assays for developmental toxicity.
    Louisse J; Gönen S; Rietjens IM; Verwei M
    Toxicol Lett; 2011 May; 203(1):1-8. PubMed ID: 21362465
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Use of Physiologically Based Kinetic Modeling-Based Reverse Dosimetry to Predict in Vivo Toxicity from in Vitro Data.
    Louisse J; Beekmann K; Rietjens IM
    Chem Res Toxicol; 2017 Jan; 30(1):114-125. PubMed ID: 27768849
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials
    Food Chem Toxicol; 2008 Mar; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro to in vivo extrapolation of effective dosimetry in developmental toxicity testing: Application of a generic PBK modelling approach.
    Fragki S; Piersma AH; Rorije E; Zeilmaker MJ
    Toxicol Appl Pharmacol; 2017 Oct; 332():109-120. PubMed ID: 28760446
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man.
    Louisse J; de Jong E; van de Sandt JJ; Blaauboer BJ; Woutersen RA; Piersma AH; Rietjens IM; Verwei M
    Toxicol Sci; 2010 Dec; 118(2):470-84. PubMed ID: 20833708
    [TBL] [Abstract][Full Text] [Related]  

  • 13. First steps in establishing a developmental toxicity test method based on human embryonic stem cells.
    Adler S; Pellizzer C; Hareng L; Hartung T; Bremer S
    Toxicol In Vitro; 2008 Feb; 22(1):200-11. PubMed ID: 17961973
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Developmental toxicity testing in the 21st century: the sword of Damocles shattered by embryonic stem cell assays?
    Seiler A; Oelgeschläger M; Liebsch M; Pirow R; Riebeling C; Tralau T; Luch A
    Arch Toxicol; 2011 Nov; 85(11):1361-72. PubMed ID: 22008952
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Predicting the in vivo developmental toxicity of benzo[a]pyrene (BaP) in rats by an in vitro-in silico approach.
    Wang D; Rietdijk MH; Kamelia L; Boogaard PJ; Rietjens IMCM
    Arch Toxicol; 2021 Oct; 95(10):3323-3340. PubMed ID: 34432120
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Principles of risk assessment for determining the safety of chemicals: recent assessment of residual solvents in drugs and di(2-ethylhexyl) phthalate.
    Hasegawa R; Koizumi M; Hirose A
    Congenit Anom (Kyoto); 2004 Jun; 44(2):51-9. PubMed ID: 15198717
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of in vitro methods as alternatives to animals in toxicity testing.
    Anadón A; Martínez MA; Castellano V; Martínez-Larrañaga MR
    Expert Opin Drug Metab Toxicol; 2014 Jan; 10(1):67-79. PubMed ID: 24160258
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Embryotoxicity hazard assessment of methylmercury and chromium using embryonic stem cells.
    Stummann TC; Hareng L; Bremer S
    Toxicology; 2007 Dec; 242(1-3):130-43. PubMed ID: 17980949
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Developmental toxicity testing for safety assessment: new approaches and technologies.
    Knudsen TB; Kavlock RJ; Daston GP; Stedman D; Hixon M; Kim JH
    Birth Defects Res B Dev Reprod Toxicol; 2011 Oct; 92(5):413-20. PubMed ID: 21770025
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Embryonic stem cell test: stem cell use in predicting developmental cardiotoxicity and osteotoxicity.
    Kuske B; Pulyanina PY; zur Nieden NI
    Methods Mol Biol; 2012; 889():147-79. PubMed ID: 22669664
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.