BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 22115332)

  • 1. Flavokawain B induces apoptosis of human oral adenoid cystic cancer ACC-2 cells via up-regulation of Bim and down-regulation of Bcl-2 expression.
    Zhao X; Chao YL; Wan QB; Chen XM; Su P; Sun J; Tang Y
    Can J Physiol Pharmacol; 2011 Dec; 89(12):875-83. PubMed ID: 22115332
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Flavokawain B, a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth.
    Tang Y; Li X; Liu Z; Simoneau AR; Xie J; Zi X
    Int J Cancer; 2010 Oct; 127(8):1758-68. PubMed ID: 20112340
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Flavokawain B, a kava chalcone, inhibits growth of human osteosarcoma cells through G2/M cell cycle arrest and apoptosis.
    Ji T; Lin C; Krill LS; Eskander R; Guo Y; Zi X; Hoang BH
    Mol Cancer; 2013 Jun; 12():55. PubMed ID: 23764122
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Flavokawain B induces apoptosis of non-small cell lung cancer H460 cells via Bax-initiated mitochondrial and JNK pathway.
    An J; Gao Y; Wang J; Zhu Q; Ma Y; Wu J; Sun J; Tang Y
    Biotechnol Lett; 2012 Oct; 34(10):1781-8. PubMed ID: 22729748
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.
    Lim DY; Park JH
    Am J Physiol Gastrointest Liver Physiol; 2009 May; 296(5):G1060-8. PubMed ID: 19264955
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice.
    Zi X; Simoneau AR
    Cancer Res; 2005 Apr; 65(8):3479-86. PubMed ID: 15833884
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prometaphase arrest-dependent phosphorylation of Bcl-2 and Bim reduces the association of Bcl-2 with Bak or Bim, provoking Bak activation and mitochondrial apoptosis in nocodazole-treated Jurkat T cells.
    Han CR; Jun do Y; Lee JY; Kim YH
    Apoptosis; 2014 Jan; 19(1):224-40. PubMed ID: 24166139
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The chalcone flavokawain B induces G2/M cell-cycle arrest and apoptosis in human oral carcinoma HSC-3 cells through the intracellular ROS generation and downregulation of the Akt/p38 MAPK signaling pathway.
    Hseu YC; Lee MS; Wu CR; Cho HJ; Lin KY; Lai GH; Wang SY; Kuo YH; Kumar KJ; Yang HL
    J Agric Food Chem; 2012 Mar; 60(9):2385-97. PubMed ID: 22324429
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chalcone flavokawain B induces autophagic-cell death via reactive oxygen species-mediated signaling pathways in human gastric carcinoma and suppresses tumor growth in nude mice.
    Chang CT; Hseu YC; Thiyagarajan V; Lin KY; Way TD; Korivi M; Liao JW; Yang HL
    Arch Toxicol; 2017 Oct; 91(10):3341-3364. PubMed ID: 28374157
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Flavokawain B, a kava chalcone, induces apoptosis in synovial sarcoma cell lines.
    Sakai T; Eskander RN; Guo Y; Kim KJ; Mefford J; Hopkins J; Bhatia NN; Zi X; Hoang BH
    J Orthop Res; 2012 Jul; 30(7):1045-50. PubMed ID: 22213202
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo.
    Lin E; Lin WH; Wang SY; Chen CS; Liao JW; Chang HW; Chen SC; Lin KY; Wang L; Yang HL; Hseu YC
    J Nutr Biochem; 2012 Apr; 23(4):368-78. PubMed ID: 21543203
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-tumour activity of a novel coumarin-chalcone hybrid is mediated through intrinsic apoptotic pathway by inducing PUMA and altering Bax/Bcl-2 ratio.
    Singh N; Sarkar J; Sashidhara KV; Ali S; Sinha S
    Apoptosis; 2014 Jun; 19(6):1017-28. PubMed ID: 24638227
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of Bim in apoptosis induced in H460 lung tumor cells by the spindle poison Combretastatin-A4.
    Mendez G; Policarpi C; Cenciarelli C; Tanzarella C; Antoccia A
    Apoptosis; 2011 Sep; 16(9):940-9. PubMed ID: 21671007
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induction of apoptosis by parthenolide in human oral cancer cell lines and tumor xenografts.
    Yu HJ; Jung JY; Jeong JH; Cho SD; Lee JS
    Oral Oncol; 2015 Jun; 51(6):602-9. PubMed ID: 25817195
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S; Borrow J; Zhang XD; Hersey P
    Apoptosis; 2006 Dec; 11(12):2251-65. PubMed ID: 17051334
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Melphalan-induced apoptosis in multiple myeloma cells is associated with a cleavage of Mcl-1 and Bim and a decrease in the Mcl-1/Bim complex.
    Gomez-Bougie P; Oliver L; Le Gouill S; Bataille R; Amiot M
    Oncogene; 2005 Dec; 24(54):8076-9. PubMed ID: 16091744
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phenylarsine oxide induces apoptosis in Bax- and Bak-deficient cells through upregulation of Bim.
    Ni B; Ma Q; Li B; Zhao L; Liu Y; Zhu Y; Chen Q
    Clin Cancer Res; 2012 Jan; 18(1):140-51. PubMed ID: 22048238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GL-V9, a newly synthetic flavonoid derivative, induces mitochondrial-mediated apoptosis and G2/M cell cycle arrest in human hepatocellular carcinoma HepG2 cells.
    Li L; Lu N; Dai Q; Wei L; Zhao Q; Li Z; He Q; Dai Y; Guo Q
    Eur J Pharmacol; 2011 Nov; 670(1):13-21. PubMed ID: 21944925
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oleanen induces apoptosis of cervical cancer cells by up-regulation of Bim.
    Gan N; Chen G; Zhang W; Zhou J
    Int J Gynecol Cancer; 2012 Jan; 22(1):38-42. PubMed ID: 21897270
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Flavokawain B, a novel, naturally occurring chalcone, exhibits robust apoptotic effects and induces G2/M arrest of a uterine leiomyosarcoma cell line.
    Eskander RN; Randall LM; Sakai T; Guo Y; Hoang B; Zi X
    J Obstet Gynaecol Res; 2012 Aug; 38(8):1086-94. PubMed ID: 22540374
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.