These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

808 related articles for article (PubMed ID: 22115830)

  • 1. Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin.
    Freeman TJ; Smith JJ; Chen X; Washington MK; Roland JT; Means AL; Eschrich SA; Yeatman TJ; Deane NG; Beauchamp RD
    Gastroenterology; 2012 Mar; 142(3):562-571.e2. PubMed ID: 22115830
    [TBL] [Abstract][Full Text] [Related]  

  • 2. OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.
    Ye GD; Sun GB; Jiao P; Chen C; Liu QF; Huang XL; Zhang R; Cai WY; Li SN; Wu JF; Liu YJ; Wu RS; Xie YY; Chan EC; Liou YC; Li BA
    Gastroenterology; 2016 Mar; 150(3):659-671.e16. PubMed ID: 26619963
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.
    Voorneveld PW; Kodach LL; Jacobs RJ; van Noesel CJ; Peppelenbosch MP; Korkmaz KS; Molendijk I; Dekker E; Morreau H; van Pelt GW; Tollenaar RA; Mesker W; Hawinkels LJ; Paauwe M; Verspaget HW; Geraets DT; Hommes DW; Offerhaus GJ; van den Brink GR; Ten Dijke P; Hardwick JC
    Br J Cancer; 2015 Jan; 112(1):122-30. PubMed ID: 25393365
    [TBL] [Abstract][Full Text] [Related]  

  • 4. TRIB3 Interacts With β-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis.
    Hua F; Shang S; Yang YW; Zhang HZ; Xu TL; Yu JJ; Zhou DD; Cui B; Li K; Lv XX; Zhang XW; Liu SS; Yu JM; Wang F; Zhang C; Huang B; Hu ZW
    Gastroenterology; 2019 Feb; 156(3):708-721.e15. PubMed ID: 30365932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.
    Peng K; Kou L; Yu L; Bai C; Li M; Mo P; Li W; Yu C
    Gastroenterology; 2019 Mar; 156(4):1112-1126. PubMed ID: 30472235
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ITF2 prevents activation of the β-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression.
    Shin HW; Choi H; So D; Kim YI; Cho K; Chung HJ; Lee KH; Chun YS; Cho CH; Kang GH; Kim WH; Park JW
    Gastroenterology; 2014 Aug; 147(2):430-442.e8. PubMed ID: 24846398
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A role for the vitamin D pathway in non-intestinal lesions in genetic and carcinogen models of colorectal cancer and in familial adenomatous polyposis.
    Bong YS; Assefnia S; Tuohy T; Neklason DW; Burt RW; Ahn J; Bueno De Mesquita PJ; Byers SW
    Oncotarget; 2016 Dec; 7(49):80508-80520. PubMed ID: 27768599
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Expression of Wnt5a, APC, β-catenin and their clinical significance in human colorectal adenocarcinoma].
    Cao YC; Yang F; Liu XH; Xin X; Wang CC; Geng M
    Zhonghua Zhong Liu Za Zhi; 2012 Sep; 34(9):674-8. PubMed ID: 23159080
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.
    Voorneveld PW; Kodach LL; Jacobs RJ; Liv N; Zonnevylle AC; Hoogenboom JP; Biemond I; Verspaget HW; Hommes DW; de Rooij K; van Noesel CJ; Morreau H; van Wezel T; Offerhaus GJ; van den Brink GR; Peppelenbosch MP; Ten Dijke P; Hardwick JC
    Gastroenterology; 2014 Jul; 147(1):196-208.e13. PubMed ID: 24704720
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer.
    Zhang Y; Guo L; Li Y; Feng GH; Teng F; Li W; Zhou Q
    Mol Cancer; 2018 Jan; 17(1):1. PubMed ID: 29304823
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In Colorectal Cancer Cells With Mutant KRAS, SLC25A22-Mediated Glutaminolysis Reduces DNA Demethylation to Increase WNT Signaling, Stemness, and Drug Resistance.
    Wong CC; Xu J; Bian X; Wu JL; Kang W; Qian Y; Li W; Chen H; Gou H; Liu D; Yat Luk ST; Zhou Q; Ji F; Chan LS; Shirasawa S; Sung JJ; Yu J
    Gastroenterology; 2020 Dec; 159(6):2163-2180.e6. PubMed ID: 32814111
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/beta-catenin signaling.
    Scholer-Dahirel A; Schlabach MR; Loo A; Bagdasarian L; Meyer R; Guo R; Woolfenden S; Yu KK; Markovits J; Killary K; Sonkin D; Yao YM; Warmuth M; Sellers WR; Schlegel R; Stegmeier F; Mosher RE; McLaughlin ME
    Proc Natl Acad Sci U S A; 2011 Oct; 108(41):17135-40. PubMed ID: 21949247
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cyclooxygenase-2 inhibitors down-regulate osteopontin and Nr4A2-new therapeutic targets for colorectal cancers.
    Zagani R; Hamzaoui N; Cacheux W; de Reyniès A; Terris B; Chaussade S; Romagnolo B; Perret C; Lamarque D
    Gastroenterology; 2009 Oct; 137(4):1358-66.e1-3. PubMed ID: 19549529
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antimetastatic role of Smad4 signaling in colorectal cancer.
    Zhang B; Halder SK; Kashikar ND; Cho YJ; Datta A; Gorden DL; Datta PK
    Gastroenterology; 2010 Mar; 138(3):969-80.e1-3. PubMed ID: 19909744
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation.
    Miguchi M; Hinoi T; Shimomura M; Adachi T; Saito Y; Niitsu H; Kochi M; Sada H; Sotomaru Y; Ikenoue T; Shigeyasu K; Tanakaya K; Kitadai Y; Sentani K; Oue N; Yasui W; Ohdan H
    PLoS One; 2016; 11(11):e0166422. PubMed ID: 27835699
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer.
    Means AL; Freeman TJ; Zhu J; Woodbury LG; Marincola-Smith P; Wu C; Meyer AR; Weaver CJ; Padmanabhan C; An H; Zi J; Wessinger BC; Chaturvedi R; Brown TD; Deane NG; Coffey RJ; Wilson KT; Smith JJ; Sawyers CL; Goldenring JR; Novitskiy SV; Washington MK; Shi C; Beauchamp RD
    Cell Mol Gastroenterol Hepatol; 2018; 6(3):257-276. PubMed ID: 30109253
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Serine-threonine Kinase Receptor-Associated Protein is a Critical Mediator of APC Mutation-Induced Intestinal Tumorigenesis Through a Feed-Forward Mechanism.
    Vu T; Datta A; Banister C; Jin L; Yuan G; Samuel T; Bae S; Eltoum IE; Manne U; Zhang B; Welner RS; Mitra K; Buckhaults P; Datta PK
    Gastroenterology; 2022 Jan; 162(1):193-208. PubMed ID: 34520730
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Loss of SMAD4 from colorectal cancer cells promotes CCL15 expression to recruit CCR1+ myeloid cells and facilitate liver metastasis.
    Itatani Y; Kawada K; Fujishita T; Kakizaki F; Hirai H; Matsumoto T; Iwamoto M; Inamoto S; Hatano E; Hasegawa S; Maekawa T; Uemoto S; Sakai Y; Taketo MM
    Gastroenterology; 2013 Nov; 145(5):1064-1075.e11. PubMed ID: 23891973
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Silibinin suppresses growth of human colorectal carcinoma SW480 cells in culture and xenograft through down-regulation of beta-catenin-dependent signaling.
    Kaur M; Velmurugan B; Tyagi A; Agarwal C; Singh RP; Agarwal R
    Neoplasia; 2010 May; 12(5):415-24. PubMed ID: 20454513
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Beta-catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors.
    Pannequin J; Delaunay N; Buchert M; Surrel F; Bourgaux JF; Ryan J; Boireau S; Coelho J; Pélegrin A; Singh P; Shulkes A; Yim M; Baldwin GS; Pignodel C; Lambeau G; Jay P; Joubert D; Hollande F
    Gastroenterology; 2007 Nov; 133(5):1554-68. PubMed ID: 17920061
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 41.