BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 22116467)

  • 1. Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration.
    Shirakami Y; Gottesman ME; Blaner WS
    Carcinogenesis; 2012 Feb; 33(2):268-74. PubMed ID: 22116467
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis.
    Kluwe J; Wongsiriroj N; Troeger JS; Gwak GY; Dapito DH; Pradere JP; Jiang H; Siddiqi M; Piantedosi R; O'Byrne SM; Blaner WS; Schwabe RF
    Gut; 2011 Sep; 60(9):1260-8. PubMed ID: 21278145
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.
    Liang S; Ma HY; Zhong Z; Dhar D; Liu X; Xu J; Koyama Y; Nishio T; Karin D; Karin G; Mccubbin R; Zhang C; Hu R; Yang G; Chen L; Ganguly S; Lan T; Karin M; Kisseleva T; Brenner DA
    Gastroenterology; 2019 Mar; 156(4):1156-1172.e6. PubMed ID: 30445007
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling.
    Sun L; Beggs K; Borude P; Edwards G; Bhushan B; Walesky C; Roy N; Manley MW; Gunewardena S; O'Neil M; Li H; Apte U
    Am J Physiol Gastrointest Liver Physiol; 2016 Jul; 311(1):G91-G104. PubMed ID: 27151938
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Non-alcoholic steatohepatitis-related liver tumorigenesis is suppressed in mice lacking hepatic retinoid storage.
    Ideta T; Shirakami Y; Ohnishi M; Maruta A; Obara K; Miyazaki T; Kochi T; Sakai H; Tomita H; Tanaka T; Blaner WS; Shimizu M
    Oncotarget; 2017 Sep; 8(41):70695-70706. PubMed ID: 29050312
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rac1 promotes diethylnitrosamine (DEN)-induced formation of liver tumors.
    Bopp A; Wartlick F; Henninger C; Schwarz M; Kaina B; Fritz G
    Carcinogenesis; 2015 Mar; 36(3):378-89. PubMed ID: 25556150
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA Alkylating Agent Protects Against Spontaneous Hepatocellular Carcinoma Regardless of O6-Methylguanine-DNA Methyltransferase Status.
    Herzig MC; Zavadil JA; Street K; Hildreth K; Drinkwater NR; Reddick T; Herbert DC; Hanes MA; McMahan CA; Reddick RL; Walter CA
    Cancer Prev Res (Phila); 2016 Mar; 9(3):245-52. PubMed ID: 26667451
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhancement of DEN-induced liver tumourigenesis in hepatocyte-specific Lass2-knockout mice coincident with upregulation of the TGF-β1-Smad4-PAI-1 axis.
    Chen L; Lu X; Zeng T; Chen Y; Chen Q; Wu W; Yan X; Cai H; Zhang Z; Shao Q; Qin W
    Oncol Rep; 2014 Feb; 31(2):885-93. PubMed ID: 24337404
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage.
    Blaner WS; O'Byrne SM; Wongsiriroj N; Kluwe J; D'Ambrosio DM; Jiang H; Schwabe RF; Hillman EM; Piantedosi R; Libien J
    Biochim Biophys Acta; 2009 Jun; 1791(6):467-73. PubMed ID: 19071229
    [TBL] [Abstract][Full Text] [Related]  

  • 10. G protein-coupled estrogen receptor deficiency accelerates liver tumorigenesis by enhancing inflammation and fibrosis.
    Wei T; Chen W; Wen L; Zhang J; Zhang Q; Yang J; Liu H; Chen BW; Zhou Y; Feng X; Yang Q; Bai X; Liang T
    Cancer Lett; 2016 Nov; 382(2):195-202. PubMed ID: 27594673
    [TBL] [Abstract][Full Text] [Related]  

  • 11. β-Catenin loss in hepatocytes promotes hepatocellular cancer after diethylnitrosamine and phenobarbital administration to mice.
    Awuah PK; Rhieu BH; Singh S; Misse A; Monga SP
    PLoS One; 2012; 7(6):e39771. PubMed ID: 22761897
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclin E facilitates dysplastic hepatocytes to bypass G1/S checkpoint in hepatocarcinogenesis.
    Pok S; Wen V; Shackel N; Alsop A; Pyakurel P; Fahrer A; Farrell GC; Teoh NC
    J Gastroenterol Hepatol; 2013 Sep; 28(9):1545-54. PubMed ID: 23574010
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hepatic retinoid stores are required for normal liver regeneration.
    Shmarakov IO; Jiang H; Yang KJ; Goldberg IJ; Blaner WS
    J Lipid Res; 2013 Apr; 54(4):893-908. PubMed ID: 23349206
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oral carcinogenesis induced by 4-nitroquinoline 1-oxide in lecithin:retinol acyltransferase gene knockout mice.
    Liu L; Tang XH; Scognamiglio T; Gudas LJ
    J Nutr Biochem; 2010 Oct; 21(10):975-82. PubMed ID: 19954945
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of hepatic lecithin:retinol acyltransferase activity by retinoic acid receptor-selective retinoids.
    Shimada T; Ross AC; Muccio DD; Brouillette WJ; Shealy YF
    Arch Biochem Biophys; 1997 Aug; 344(1):220-7. PubMed ID: 9244401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Retinoids modulate thioacetamide-induced acute hepatotoxicity.
    Shmarakov IO; Borschovetska VL; Marchenko MM; Blaner WS
    Toxicol Sci; 2014 Jun; 139(2):284-92. PubMed ID: 24614237
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Overexpression of lecithin:retinol acyltransferase in the epithelial basal layer makes mice more sensitive to oral cavity carcinogenesis induced by a carcinogen.
    Tang XH; Su D; Albert M; Scognamiglio T; Gudas LJ
    Cancer Biol Ther; 2009 Jul; 8(13):1212-3. PubMed ID: 19471114
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT).
    O'Byrne SM; Wongsiriroj N; Libien J; Vogel S; Goldberg IJ; Baehr W; Palczewski K; Blaner WS
    J Biol Chem; 2005 Oct; 280(42):35647-57. PubMed ID: 16115871
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis.
    Teoh N; Pyakurel P; Dan YY; Swisshelm K; Hou J; Mitchell C; Fausto N; Gu Y; Farrell G
    Gastroenterology; 2010 Mar; 138(3):1155-65.e1-2. PubMed ID: 19919837
    [TBL] [Abstract][Full Text] [Related]  

  • 20. LRAT overexpression diminishes intracellular levels of biologically active retinoids and reduces retinoid antitumor efficacy in the murine melanoma B16F10 cell line.
    Amann PM; Czaja K; Bazhin AV; Rühl R; Eichmüller SB; Merk HF; Baron JM
    Skin Pharmacol Physiol; 2015; 28(4):205-212. PubMed ID: 25721651
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.