These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 2211701)

  • 1. Methotrexate transport in variant human CCRF-CEM leukemia cells with elevated levels of the reduced folate carrier. Selective effect on carrier-mediated transport of physiological concentrations of reduced folates.
    Jansen G; Westerhof GR; Jarmuszewski MJ; Kathmann I; Rijksen G; Schornagel JH
    J Biol Chem; 1990 Oct; 265(30):18272-7. PubMed ID: 2211701
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.
    Jansen G; Mauritz RM; Assaraf YG; Sprecher H; Drori S; Kathmann I; Westerhof GR; Priest DG; Bunni M; Pinedo HM; Schornagel JH; Peters GJ
    Adv Enzyme Regul; 1997; 37():59-76. PubMed ID: 9381986
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular events in the membrane transport of methotrexate in human CCRF-CEM leukemia cell lines.
    Freisheim JH; Ratnam M; McAlinden TP; Prasad KM; Williams FE; Westerhof GR; Schornagel JH; Jansen G
    Adv Enzyme Regul; 1992; 32():17-31. PubMed ID: 1323203
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance.
    Jansen G; Westerhof GR; Kathmann I; Rademaker BC; Rijksen G; Schornagel JH
    Cancer Res; 1989 May; 49(9):2455-9. PubMed ID: 2706633
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Further studies on a novel class of genetic variants of the L1210 cell with increased folate analogue transport inward. Transport properties of a new variant, evidence for increased levels of a specific transport protein, and its partial characterization following affinity labeling.
    Yang CH; Sirotnak FM; Mines LS
    J Biol Chem; 1988 Jul; 263(20):9703-9. PubMed ID: 2838477
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 5,10-Dideazatetrahydrofolic acid (DDATHF) transport in CCRF-CEM and MA104 cell lines.
    Pizzorno G; Cashmore AR; Moroson BA; Cross AD; Smith AK; Marling-Cason M; Kamen BA; Beardsley GP
    J Biol Chem; 1993 Jan; 268(2):1017-23. PubMed ID: 8419310
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.
    Jansen G; Mauritz R; Drori S; Sprecher H; Kathmann I; Bunni M; Priest DG; Noordhuis P; Schornagel JH; Pinedo HM; Peters GJ; Assaraf YG
    J Biol Chem; 1998 Nov; 273(46):30189-98. PubMed ID: 9804775
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Determinants of the disparate antitumor activities of (6R)-5,10-dideaza-5,6,7,8-tetrahydrofolate and methotrexate toward human lymphoblastic leukemia cells, characterized by severely impaired antifolate membrane transport.
    Matherly LH; Angeles SM; McGuire JJ
    Biochem Pharmacol; 1993 Dec; 46(12):2185-95. PubMed ID: 7506026
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transport of folate compounds by leukemic cells. Evidence for a single influx carrier for methotrexate, 5-methyltetrahydrofolate, and folate in CCRF-CEM human lymphoblasts.
    Henderson GB; Tsuji JM; Kumar HP
    Biochem Pharmacol; 1987 Sep; 36(18):3007-14. PubMed ID: 3477231
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple membrane transport systems for the uptake of folate-based thymidylate synthase inhibitors.
    Jansen G; Schornagel JH; Westerhof GR; Rijksen G; Newell DR; Jackman AL
    Cancer Res; 1990 Dec; 50(23):7544-8. PubMed ID: 2253202
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytotoxicity of trimetrexate against antifolate-resistant human T-cell leukemia cell lines developed in oxidized or reduced folate.
    Miyachi H; Takemura Y; Kobayashi H; Ando Y
    Jpn J Cancer Res; 1997 Sep; 88(9):900-6. PubMed ID: 9369939
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytotoxicity of methotrexate and trimetrexate and its reversal by folinic acid in human leukemic CCRF-CEM cells with carrier-mediated and receptor-mediated folate uptake.
    van der Veer LJ; Westerhof GR; Rijksen G; Schornagel JH; Jansen G
    Leuk Res; 1989; 13(11):981-7. PubMed ID: 2532692
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Membrane transport of natural folates and antifolate compounds in murine L1210 leukemia cells: role of carrier- and receptor-mediated transport systems.
    Westerhof GR; Jansen G; van Emmerik N; Kathmann I; Rijksen G; Jackman AL; Schornagel JH
    Cancer Res; 1991 Oct; 51(20):5507-13. PubMed ID: 1655252
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein.
    Westerhof GR; Rijnboutt S; Schornagel JH; Pinedo HM; Peters GJ; Jansen G
    Cancer Res; 1995 Sep; 55(17):3795-802. PubMed ID: 7641196
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Clustering of mutations in the first transmembrane domain of the human reduced folate carrier in GW1843U89-resistant leukemia cells with impaired antifolate transport and augmented folate uptake.
    Drori S; Jansen G; Mauritz R; Peters GJ; Assaraf YG
    J Biol Chem; 2000 Oct; 275(40):30855-63. PubMed ID: 10899164
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells.
    Assaraf YG; Rothem L; Hooijberg JH; Stark M; Ifergan I; Kathmann I; Dijkmans BA; Peters GJ; Jansen G
    J Biol Chem; 2003 Feb; 278(9):6680-6. PubMed ID: 12486126
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Folate transport and the modulation of antifolate sensitivity in a methotrexate-resistant human breast cancer cell line.
    Dixon KH; Trepel JB; Eng SC; Cowan KH
    Cancer Commun; 1991; 3(12):357-65. PubMed ID: 16296001
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
    Mauritz R; Peters GJ; Priest DG; Assaraf YG; Drori S; Kathmann I; Noordhuis P; Bunni MA; Rosowsky A; Schornagel JH; Pinedo HM; Jansen G
    Biochem Pharmacol; 2002 Jan; 63(2):105-15. PubMed ID: 11841783
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Carrier-mediated transport of folate compounds in L1210 cells. Initial rate kinetics and extent of duality of entry routes for folic acid and diastereomers of 5-methyltetrahydrohomofolate in the presence of physiological anions.
    Sirotnak FM; Goutas LJ; Jacobsen DM; Mines LS; Barrueco JR; Gaumont Y; Kisliuk RL
    Biochem Pharmacol; 1987 May; 36(10):1659-67. PubMed ID: 3593392
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of folate receptor expression following stable transfection into wild type and methotrexate transport-deficient ZR-75-1 human breast cancer cells.
    Dixon KH; Mulligan T; Chung KN; Elwood PC; Cowan KH
    J Biol Chem; 1992 Nov; 267(33):24140-7. PubMed ID: 1429743
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.