These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 22117045)

  • 1. Inhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPH.
    Yin L; Kosugi M; Kufe D
    Blood; 2012 Jan; 119(3):810-6. PubMed ID: 22117045
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting MUC1-C is synergistic with bortezomib in downregulating TIGAR and inducing ROS-mediated myeloma cell death.
    Yin L; Kufe T; Avigan D; Kufe D
    Blood; 2014 May; 123(19):2997-3006. PubMed ID: 24632713
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting MUC1-C inhibits the AKT-S6K1-elF4A pathway regulating TIGAR translation in colorectal cancer.
    Ahmad R; Alam M; Hasegawa M; Uchida Y; Al-Obaid O; Kharbanda S; Kufe D
    Mol Cancer; 2017 Feb; 16(1):33. PubMed ID: 28153010
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mucin 1 is a potential therapeutic target in cutaneous T-cell lymphoma.
    Jain S; Stroopinsky D; Yin L; Rosenblatt J; Alam M; Bhargava P; Clark RA; Kupper TS; Palmer K; Coll MD; Rajabi H; Pyzer A; Bar-Natan M; Luptakova K; Arnason J; Joyce R; Kufe D; Avigan D
    Blood; 2015 Jul; 126(3):354-62. PubMed ID: 26048911
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death.
    Cheung EC; Ludwig RL; Vousden KH
    Proc Natl Acad Sci U S A; 2012 Dec; 109(50):20491-6. PubMed ID: 23185017
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα.
    Sinha S; Ghildiyal R; Mehta VS; Sen E
    Cell Death Dis; 2013 May; 4(5):e615. PubMed ID: 23640457
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MUC1-C is a target in lenalidomide resistant multiple myeloma.
    Yin L; Tagde A; Gali R; Tai YT; Hideshima T; Anderson K; Avigan D; Kufe D
    Br J Haematol; 2017 Sep; 178(6):914-926. PubMed ID: 28643330
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis.
    Wanka C; Steinbach JP; Rieger J
    J Biol Chem; 2012 Sep; 287(40):33436-46. PubMed ID: 22887998
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TIGAR mediates the inhibitory role of hypoxia on ROS production and apoptosis in rat nucleus pulposus cells.
    Jiang LB; Cao L; Ma YQ; Chen Q; Liang Y; Yuan FL; Li XL; Dong J; Chen N
    Osteoarthritis Cartilage; 2018 Jan; 26(1):138-148. PubMed ID: 29061494
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Survival of human multiple myeloma cells is dependent on MUC1 C-terminal transmembrane subunit oncoprotein function.
    Yin L; Ahmad R; Kosugi M; Kufe T; Vasir B; Avigan D; Kharbanda S; Kufe D
    Mol Pharmacol; 2010 Aug; 78(2):166-74. PubMed ID: 20444960
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation.
    Yin L; Kharbanda S; Kufe D
    Int J Oncol; 2009 Jun; 34(6):1691-9. PubMed ID: 19424588
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TIGAR regulates glycolysis in ischemic kidney proximal tubules.
    Kim J; Devalaraja-Narashimha K; Padanilam BJ
    Am J Physiol Renal Physiol; 2015 Feb; 308(4):F298-308. PubMed ID: 25503731
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of MUC1-C regulates metabolism by AKT pathway in esophageal squamous cell carcinoma.
    GongSun X; Zhao Y; Jiang B; Xin Z; Shi M; Song L; Qin Q; Wang Q; Liu X
    J Cell Physiol; 2019 Jul; 234(7):12019-12028. PubMed ID: 30523643
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TP53 induced glycolysis and apoptosis regulator (TIGAR) knockdown results in radiosensitization of glioma cells.
    Peña-Rico MA; Calvo-Vidal MN; Villalonga-Planells R; Martínez-Soler F; Giménez-Bonafé P; Navarro-Sabaté À; Tortosa A; Bartrons R; Manzano A
    Radiother Oncol; 2011 Oct; 101(1):132-9. PubMed ID: 21864926
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of intracellular ROS levels by TIGAR controls autophagy.
    Bensaad K; Cheung EC; Vousden KH
    EMBO J; 2009 Oct; 28(19):3015-26. PubMed ID: 19713938
    [TBL] [Abstract][Full Text] [Related]  

  • 16. TIGAR, a p53-inducible regulator of glycolysis and apoptosis.
    Bensaad K; Tsuruta A; Selak MA; Vidal MN; Nakano K; Bartrons R; Gottlieb E; Vousden KH
    Cell; 2006 Jul; 126(1):107-20. PubMed ID: 16839880
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells.
    Kawano T; Ahmad R; Nogi H; Agata N; Anderson K; Kufe D
    Int J Oncol; 2008 Jul; 33(1):153-9. PubMed ID: 18575761
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death.
    Lui VW; Wong EY; Ho K; Ng PK; Lau CP; Tsui SK; Tsang CM; Tsao SW; Cheng SH; Ng MH; Ng YK; Lam EK; Hong B; Lo KW; Mok TS; Chan AT; Mills GB
    Oncogene; 2011 Mar; 30(9):1127-34. PubMed ID: 21057531
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The human T-cell leukemia virus type-1 p30
    Romeo M; Hutchison T; Malu A; White A; Kim J; Gardner R; Smith K; Nelson K; Bergeson R; McKee R; Harrod C; Ratner L; Lüscher B; Martinez E; Harrod R
    Virology; 2018 May; 518():103-115. PubMed ID: 29462755
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MUC1-C oncoprotein suppresses reactive oxygen species-induced terminal differentiation of acute myelogenous leukemia cells.
    Yin L; Wu Z; Avigan D; Rosenblatt J; Stone R; Kharbanda S; Kufe D
    Blood; 2011 May; 117(18):4863-70. PubMed ID: 21422470
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.