These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 22117046)

  • 1. Inhibition of histone methylation arrests ongoing graft-versus-host disease in mice by selectively inducing apoptosis of alloreactive effector T cells.
    He S; Wang J; Kato K; Xie F; Varambally S; Mineishi S; Kuick R; Mochizuki K; Liu Y; Nieves E; Mani RS; Chinnaiyan AM; Marquez VE; Zhang Y
    Blood; 2012 Feb; 119(5):1274-82. PubMed ID: 22117046
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modulation of allogeneic CD8+ T-cell response by DZNep controls GVHD while preserving hematopoietic chimerism.
    Wang J; Li L; Xu M; Rong R; Zhu T
    Transplantation; 2013 Nov; 96(9):774-81. PubMed ID: 23900211
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in mice.
    Huang Q; He S; Tian Y; Gu Y; Chen P; Li C; Huang J; Liu Y; Yu H; Jin M; Hu S; Tong Q; Ma A; Jin J; Hexner E; Fung H; Reshef R; Zhang Y; Zhang Y
    Blood; 2017 May; 129(20):2737-2748. PubMed ID: 28246193
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The histone methyltransferase Ezh2 is a crucial epigenetic regulator of allogeneic T-cell responses mediating graft-versus-host disease.
    He S; Xie F; Liu Y; Tong Q; Mochizuki K; Lapinski PE; Mani RS; Reddy P; Mochizuki I; Chinnaiyan AM; Mineishi S; King PD; Zhang Y
    Blood; 2013 Dec; 122(25):4119-28. PubMed ID: 24141370
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of stem cell transcriptional programs normally expressed in embryonic and neural stem cells in alloreactive CD8+ T cells mediating graft-versus-host disease.
    Kato K; Cui S; Kuick R; Mineishi S; Hexner E; Ferrara JL; Emerson SG; Zhang Y
    Biol Blood Marrow Transplant; 2010 Jun; 16(6):751-71. PubMed ID: 20116439
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 3-Deazaneplanocin A (DZNep), an inhibitor of the histone methyltransferase EZH2, induces apoptosis and reduces cell migration in chondrosarcoma cells.
    Girard N; Bazille C; Lhuissier E; Benateau H; Llombart-Bosch A; Boumediene K; Bauge C
    PLoS One; 2014; 9(5):e98176. PubMed ID: 24852755
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation.
    Alahmari B; Cooper M; Ziga E; Ritchey J; DiPersio JF; Choi J
    PLoS One; 2018; 13(11):e0207609. PubMed ID: 30452487
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells.
    Fiskus W; Wang Y; Sreekumar A; Buckley KM; Shi H; Jillella A; Ustun C; Rao R; Fernandez P; Chen J; Balusu R; Koul S; Atadja P; Marquez VE; Bhalla KN
    Blood; 2009 Sep; 114(13):2733-43. PubMed ID: 19638619
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.
    Miranda TB; Cortez CC; Yoo CB; Liang G; Abe M; Kelly TK; Marquez VE; Jones PA
    Mol Cancer Ther; 2009 Jun; 8(6):1579-88. PubMed ID: 19509260
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 3-deazaneplanocin A protects against cisplatin-induced renal tubular cell apoptosis and acute kidney injury by restoration of E-cadherin expression.
    Ni J; Hou X; Wang X; Shi Y; Xu L; Zheng X; Liu N; Qiu A; Zhuang S
    Cell Death Dis; 2019 May; 10(5):355. PubMed ID: 31043583
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Murine acute graft-versus-host disease can be prevented by depletion of alloreactive T lymphocytes using activation-induced cell death.
    Hartwig UF; Robbers M; Wickenhauser C; Huber C
    Blood; 2002 Apr; 99(8):3041-9. PubMed ID: 11929798
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies.
    Hung SW; Mody H; Marrache S; Bhutia YD; Davis F; Cho JH; Zastre J; Dhar S; Chu CK; Govindarajan R
    PLoS One; 2013; 8(8):e71196. PubMed ID: 23940717
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML.
    Zhou J; Bi C; Cheong LL; Mahara S; Liu SC; Tay KG; Koh TL; Yu Q; Chng WJ
    Blood; 2011 Sep; 118(10):2830-9. PubMed ID: 21734239
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A.
    Zeybel M; Luli S; Sabater L; Hardy T; Oakley F; Leslie J; Page A; Moran Salvador E; Sharkey V; Tsukamoto H; Chu DCK; Singh US; Ponzoni M; Perri P; Di Paolo D; Mendivil EJ; Mann J; Mann DA
    Mol Ther; 2017 Jan; 25(1):218-231. PubMed ID: 28129116
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chromatin remodeling by the histone methyltransferase EZH2 drives lung pre-malignancy and is a target for cancer prevention.
    Tellez CS; Picchi MA; Juri D; Do K; Desai DH; Amin SG; Hutt JA; Filipczak PT; Belinsky SA
    Clin Epigenetics; 2021 Feb; 13(1):44. PubMed ID: 33632299
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone deacetylase inhibition modulates indoleamine 2,3-dioxygenase-dependent DC functions and regulates experimental graft-versus-host disease in mice.
    Reddy P; Sun Y; Toubai T; Duran-Struuck R; Clouthier SG; Weisiger E; Maeda Y; Tawara I; Krijanovski O; Gatza E; Liu C; Malter C; Mascagni P; Dinarello CA; Ferrara JL
    J Clin Invest; 2008 Jul; 118(7):2562-73. PubMed ID: 18568076
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Anti-leukemic effects of HDACi Belinostat and HMTi 3-Deazaneplanocin A on human acute promyelocytic leukemia cells.
    Valiulienė G; Stirblytė I; Jasnauskaitė M; Borutinskaitė V; Navakauskienė R
    Eur J Pharmacol; 2017 Mar; 799():143-153. PubMed ID: 28192098
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DZNep, inhibitor of S-adenosylhomocysteine hydrolase, down-regulates expression of SETDB1 H3K9me3 HMTase in human lung cancer cells.
    Lee JK; Kim KC
    Biochem Biophys Res Commun; 2013 Sep; 438(4):647-52. PubMed ID: 23933322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of histone methyltransferase EZH2 ameliorates early acute renal allograft rejection in rats.
    Li L; Zhang Y; Xu M; Rong R; Wang J; Zhu T
    BMC Immunol; 2016 Oct; 17(1):41. PubMed ID: 27784285
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alloreactive memory T cells are responsible for the persistence of graft-versus-host disease.
    Zhang Y; Joe G; Hexner E; Zhu J; Emerson SG
    J Immunol; 2005 Mar; 174(5):3051-8. PubMed ID: 15728519
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.