BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 22117067)

  • 1. Molecular and cellular effects of Tamm-Horsfall protein mutations and their rescue by chemical chaperones.
    Ma L; Liu Y; El-Achkar TM; Wu XR
    J Biol Chem; 2012 Jan; 287(2):1290-305. PubMed ID: 22117067
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Defective intracellular trafficking of uromodulin mutant isoforms.
    Bernascone I; Vavassori S; Di Pentima A; Santambrogio S; Lamorte G; Amoroso A; Scolari F; Ghiggeri GM; Casari G; Polishchuk R; Rampoldi L
    Traffic; 2006 Nov; 7(11):1567-79. PubMed ID: 17010121
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutant tamm-horsfall glycoprotein accumulation in endoplasmic reticulum induces apoptosis reversed by colchicine and sodium 4-phenylbutyrate.
    Choi SW; Ryu OH; Choi SJ; Song IS; Bleyer AJ; Hart TC
    J Am Soc Nephrol; 2005 Oct; 16(10):3006-14. PubMed ID: 16135773
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.
    Gautherot J; Durand-Schneider AM; Delautier D; Delaunay JL; Rada A; Gabillet J; Housset C; Maurice M; Aït-Slimane T
    J Biol Chem; 2012 Feb; 287(7):5070-8. PubMed ID: 22184139
    [TBL] [Abstract][Full Text] [Related]  

  • 5. No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.
    Kemter E; Sklenak S; Rathkolb B; Hrabě de Angelis M; Wolf E; Aigner B; Wanke R
    J Biol Chem; 2014 Apr; 289(15):10715-10726. PubMed ID: 24567330
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Wild-type uromodulin prevents NFkB activation in kidney cells, while mutant uromodulin, causing FJHU nephropathy, does not.
    Dinour D; Ganon L; Nomy LI; Ron R; Holtzman EJ
    J Nephrol; 2014 Jun; 27(3):257-64. PubMed ID: 24648000
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rescue of vasopressin V2 receptor mutants by chemical chaperones: specificity and mechanism.
    Robben JH; Sze M; Knoers NV; Deen PM
    Mol Biol Cell; 2006 Jan; 17(1):379-86. PubMed ID: 16267275
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant uromodulin expression leads to altered homeostasis of the endoplasmic reticulum and activates the unfolded protein response.
    Schaeffer C; Merella S; Pasqualetto E; Lazarevic D; Rampoldi L
    PLoS One; 2017; 12(4):e0175970. PubMed ID: 28437467
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tamm-Horsfall glycoprotein interacts with renal outer medullary potassium channel ROMK2 and regulates its function.
    Renigunta A; Renigunta V; Saritas T; Decher N; Mutig K; Waldegger S
    J Biol Chem; 2011 Jan; 286(3):2224-35. PubMed ID: 21081491
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Point mutation in D8C domain of Tamm-Horsfall protein/uromodulin in transgenic mice causes progressive renal damage and hyperuricemia.
    Ma L; Liu Y; Landry NK; El-Achkar TM; Lieske JC; Wu XR
    PLoS One; 2017; 12(11):e0186769. PubMed ID: 29145399
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance.
    Bush KT; Goldberg AL; Nigam SK
    J Biol Chem; 1997 Apr; 272(14):9086-92. PubMed ID: 9083035
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell surface rescue of kidney anion exchanger 1 mutants by disruption of chaperone interactions.
    Patterson ST; Reithmeier RAF
    J Biol Chem; 2010 Oct; 285(43):33423-33434. PubMed ID: 20628050
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tamm-Horsfall Protein is a Potent Immunomodulatory Molecule and a Disease Biomarker in the Urinary System.
    Wu TH; Li KJ; Yu CL; Tsai CY
    Molecules; 2018 Jan; 23(1):. PubMed ID: 29361765
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutations in intracellular loops 1 and 3 lead to misfolding of human P-glycoprotein (ABCB1) that can be rescued by cyclosporine A, which reduces its association with chaperone Hsp70.
    Kapoor K; Bhatnagar J; Chufan EE; Ambudkar SV
    J Biol Chem; 2013 Nov; 288(45):32622-32636. PubMed ID: 24064216
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The kidney protects against sepsis by producing systemic uromodulin.
    LaFavers KA; Hage CA; Gaur V; Micanovic R; Hato T; Khan S; Winfree S; Doshi S; Moorthi RN; Twigg H; Wu XR; Dagher PC; Srour EF; El-Achkar TM
    Am J Physiol Renal Physiol; 2022 Aug; 323(2):F212-F226. PubMed ID: 35759740
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum.
    Williams SE; Reed AA; Galvanovskis J; Antignac C; Goodship T; Karet FE; Kotanko P; Lhotta K; Morinière V; Williams P; Wong W; Rorsman P; Thakker RV
    Hum Mol Genet; 2009 Aug; 18(16):2963-74. PubMed ID: 19465746
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosis.
    Yam GH; Gaplovska-Kysela K; Zuber C; Roth J
    Invest Ophthalmol Vis Sci; 2007 Apr; 48(4):1683-90. PubMed ID: 17389500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hsp70 promotes epithelial sodium channel functional expression by increasing its association with coat complex II and its exit from endoplasmic reticulum.
    Chanoux RA; Robay A; Shubin CB; Kebler C; Suaud L; Rubenstein RC
    J Biol Chem; 2012 Jun; 287(23):19255-65. PubMed ID: 22496374
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tamm-Horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an MIP-2-dependent mechanism.
    El-Achkar TM; McCracken R; Rauchman M; Heitmeier MR; Al-Aly Z; Dagher PC; Wu XR
    Am J Physiol Renal Physiol; 2011 Apr; 300(4):F999-1007. PubMed ID: 21228114
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tamm-Horsfall protein/uromodulin deficiency elicits tubular compensatory responses leading to hypertension and hyperuricemia.
    Liu Y; Goldfarb DS; El-Achkar TM; Lieske JC; Wu XR
    Am J Physiol Renal Physiol; 2018 Jun; 314(6):F1062-F1076. PubMed ID: 29357410
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.