172 related articles for article (PubMed ID: 22118226)
1. Cytochrome P450-mediated metabolism and DNA binding of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline and its carcinogenic isomer 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in mice.
Turesky RJ; Bessette EE; Dunbar D; Liberman RG; Skipper PL
Chem Res Toxicol; 2012 Feb; 25(2):410-21. PubMed ID: 22118226
[TBL] [Abstract][Full Text] [Related]
2. Regioselective differences in C(8)- and N-oxidation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline by human and rat liver microsomes and cytochromes P450 1A2.
Turesky RJ; Parisod V; Huynh-Ba T; Langouët S; Guengerich FP
Chem Res Toxicol; 2001 Jul; 14(7):901-11. PubMed ID: 11453738
[TBL] [Abstract][Full Text] [Related]
3. Metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in human hepatocytes: 2-amino-3-methylimidazo[4,5-f]quinoxaline-8-carboxylic acid is a major detoxification pathway catalyzed by cytochrome P450 1A2.
Langouët S; Welti DH; Kerriguy N; Fay LB; Huynh-Ba T; Markovic J; Guengerich FP; Guillouzo A; Turesky RJ
Chem Res Toxicol; 2001 Feb; 14(2):211-21. PubMed ID: 11258970
[TBL] [Abstract][Full Text] [Related]
4. Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.
Turesky RJ; Constable A; Richoz J; Varga N; Markovic J; Martin MV; Guengerich FP
Chem Res Toxicol; 1998 Aug; 11(8):925-36. PubMed ID: 9705755
[TBL] [Abstract][Full Text] [Related]
5. Analysis and quantification of DNA adducts of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in liver of rats by liquid chromatography/electrospray tandem mass spectrometry.
Paehler A; Richoz J; Soglia J; Vouros P; Turesky RJ
Chem Res Toxicol; 2002 Apr; 15(4):551-61. PubMed ID: 11952342
[TBL] [Abstract][Full Text] [Related]
6. Identification of 2-amino-1,7-dimethylimidazo[4,5-g]quinoxaline: an abundant mutagenic heterocyclic aromatic amine formed in cooked beef.
Turesky RJ; Goodenough AK; Ni W; McNaughton L; LeMaster DM; Holland RD; Wu RW; Felton JS
Chem Res Toxicol; 2007 Mar; 20(3):520-30. PubMed ID: 17316027
[TBL] [Abstract][Full Text] [Related]
7. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
Turesky RJ; Lang NP; Butler MA; Teitel CH; Kadlubar FF
Carcinogenesis; 1991 Oct; 12(10):1839-45. PubMed ID: 1934265
[TBL] [Abstract][Full Text] [Related]
8. Dose-response studies of MeIQx in rat liver and liver DNA at low doses.
Frantz CE; Bangerter C; Fultz E; Mayer KM; Vogel JS; Turteltaub KW
Carcinogenesis; 1995 Feb; 16(2):367-73. PubMed ID: 7859370
[TBL] [Abstract][Full Text] [Related]
9. The effect of dose and cytochrome P450 induction on the metabolism and disposition of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f] quinoxaline (MeIQx) in the rat.
Turesky RJ; Markovic J; Bracco-Hammer I; Fay LB
Carcinogenesis; 1991 Oct; 12(10):1847-55. PubMed ID: 1934266
[TBL] [Abstract][Full Text] [Related]
10. A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
Gu D; McNaughton L; Lemaster D; Lake BG; Gooderham NJ; Kadlubar FF; Turesky RJ
Chem Res Toxicol; 2010 Apr; 23(4):788-801. PubMed ID: 20192249
[TBL] [Abstract][Full Text] [Related]
11. N-hydroxy-MeIQx is the major microsomal oxidation product of the dietary carcinogen MeIQx with human liver.
Rich KJ; Murray BP; Lewis I; Rendell NB; Davies DS; Gooderham NJ; Boobis AR
Carcinogenesis; 1992 Dec; 13(12):2221-6. PubMed ID: 1473228
[TBL] [Abstract][Full Text] [Related]
12. Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
Sadrieh N; Snyderwine EG
Carcinogenesis; 1995 Jul; 16(7):1549-55. PubMed ID: 7614688
[TBL] [Abstract][Full Text] [Related]
13. Metabolism of the food-borne mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans.
Turesky RJ; Garner RC; Welti DH; Richoz J; Leveson SH; Dingley KH; Turteltaub KW; Fay LB
Chem Res Toxicol; 1998 Mar; 11(3):217-25. PubMed ID: 9544620
[TBL] [Abstract][Full Text] [Related]
14. N-oxidative metabolism of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in humans: excretion of the N2-glucuronide conjugate of 2-hydroxyamino-MeIQx in urine.
Stillwell WG; Turesky RJ; Sinha R; Tannenbaum SR
Cancer Res; 1999 Oct; 59(20):5154-9. PubMed ID: 10537291
[TBL] [Abstract][Full Text] [Related]
15. Metabolic Activation of the Cooked Meat Carcinogen 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine in Human Prostate.
Bellamri M; Xiao S; Murugan P; Weight CJ; Turesky RJ
Toxicol Sci; 2018 Jun; 163(2):543-556. PubMed ID: 29596660
[TBL] [Abstract][Full Text] [Related]
16. DNA adducts of the tobacco carcinogens 2-amino-9H-pyrido[2,3-b]indole and 4-aminobiphenyl are formed at environmental exposure levels and persist in human hepatocytes.
Nauwelaërs G; Bellamri M; Fessard V; Turesky RJ; Langouët S
Chem Res Toxicol; 2013 Sep; 26(9):1367-77. PubMed ID: 23898916
[TBL] [Abstract][Full Text] [Related]
17. In vivo mutagenicity and hepatocarcinogenicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in bitransgenic c-myc/lambda lacZ mice.
Ryu DY; Pratt VS; Davis CD; Schut HA; Snyderwine EG
Cancer Res; 1999 Jun; 59(11):2587-92. PubMed ID: 10363978
[TBL] [Abstract][Full Text] [Related]
18. Formation and removal of DNA adducts in the liver of rats chronically fed the food-borne carcinogen, 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline.
Hirose M; Wakabayashi K; Ochiai M; Kushida H; Sato H; Sugimura T; Nagao M
Jpn J Cancer Res; 1995 Jun; 86(6):516-22. PubMed ID: 7622414
[TBL] [Abstract][Full Text] [Related]
19. MeIQx-DNA adduct formation in rodent and human tissues at low doses.
Turteltaub KW; Mauthe RJ; Dingley KH; Vogel JS; Frantz CE; Garner RC; Shen N
Mutat Res; 1997 May; 376(1-2):243-52. PubMed ID: 9202761
[TBL] [Abstract][Full Text] [Related]
20. Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.
Snyderwine EG; Turesky RJ; Buonarati MH; Turteltaub KW; Adamson RH
Princess Takamatsu Symp; 1995; 23():69-77. PubMed ID: 8844797
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
