BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 22118226)

  • 21. Human T lymphocytes bioactivate heterocyclic aromatic amines by forming DNA adducts.
    Bellamri M; Le Hegarat L; Vernhet L; Baffet G; Turesky RJ; Langouët S
    Environ Mol Mutagen; 2016 Dec; 57(9):656-667. PubMed ID: 27801952
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The contribution of N-oxidation to the metabolism of the food-borne carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in rat hepatocytes.
    Turesky RJ; Bracco-Hammer I; Markovic J; Richli U; Kappeler AM; Welti DH
    Chem Res Toxicol; 1990; 3(6):524-35. PubMed ID: 2103323
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Effect of N-acetyltransferase 2 polymorphism on tumor target tissue DNA adduct levels in rapid and slow acetylator congenic rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine or 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline.
    Metry KJ; Neale JR; Bendaly J; Smith NB; Pierce WM; Hein DW
    Drug Metab Dispos; 2009 Nov; 37(11):2123-6. PubMed ID: 19666988
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Metabolism of heterocyclic aromatic amines and strategies of human biomonitoring.
    Turesky RJ; Fay LB; Welti DH
    Princess Takamatsu Symp; 1995; 23():59-68. PubMed ID: 8844796
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Stability and reactivity of 2-nitrosoamino-3,8-dimethylimidazo[4,5-f]quinoxaline.
    Lakshmi VM; Hsu FF; Schut HA; Zenser TV
    Chem Res Toxicol; 2006 Feb; 19(2):325-33. PubMed ID: 16485910
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.
    Turesky RJ; Guengerich FP; Guillouzo A; Langouët S
    Mutat Res; 2002 Sep; 506-507():187-95. PubMed ID: 12351158
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Disposition of the Dietary Mutagen 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline in Healthy and Pancreatic Cancer Compromised Humans.
    Malfatti MA; Kuhn EA; Turteltaub KW; Vickers SM; Jensen EH; Strayer L; Anderson KE
    Chem Res Toxicol; 2016 Mar; 29(3):352-8. PubMed ID: 26918625
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Presence of N2-(deoxyguanosin-8-yl)-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (dG-C8-MeIQx) in human tissues.
    Totsuka Y; Fukutome K; Takahashi M; Takahashi S; Tada A; Sugimura T; Wakabayashi K
    Carcinogenesis; 1996 May; 17(5):1029-34. PubMed ID: 8640908
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo.
    Davis CD; Schut HA; Adamson RH; Thorgeirsson UP; Thorgeirsson SS; Snyderwine EG
    Carcinogenesis; 1993 Jan; 14(1):61-5. PubMed ID: 8425272
    [TBL] [Abstract][Full Text] [Related]  

  • 30. 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.
    Arlt VM; Hewer A; Sorg BL; Schmeiser HH; Phillips DH; Stiborova M
    Chem Res Toxicol; 2004 Aug; 17(8):1092-101. PubMed ID: 15310241
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Caffeine Cytochrome P450 1A2 Metabolic Phenotype Does Not Predict the Metabolism of Heterocyclic Aromatic Amines in Humans.
    Turesky RJ; White KK; Wilkens LR; Le Marchand L
    Chem Res Toxicol; 2015 Aug; 28(8):1603-15. PubMed ID: 26203673
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Characterization of DNA adducts formed in vitro by reaction of N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline and N-hydroxy-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline at the C-8 and N2 atoms of guanine.
    Turesky RJ; Rossi SC; Welti DH; Lay JO; Kadlubar FF
    Chem Res Toxicol; 1992; 5(4):479-90. PubMed ID: 1391614
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Macromolecular adduct formation and metabolism of heterocyclic amines in humans and rodents at low doses.
    Turteltaub KW; Dingley KH; Curtis KD; Malfatti MA; Turesky RJ; Garner RC; Felton JS; Lang NP
    Cancer Lett; 1999 Sep; 143(2):149-55. PubMed ID: 10503895
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Intra- and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl- 6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef.
    Lynch AM; Knize MG; Boobis AR; Gooderham NJ; Davies DS; Murray S
    Cancer Res; 1992 Nov; 52(22):6216-23. PubMed ID: 1423264
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The food mutagen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline: a conformational analysis of its major DNA adduct and comparison with the 2-amino-3-methylimidazo[4,5-f]quinoline adduct.
    Gauvin J; Broyde S; Shapiro R
    Chem Res Toxicol; 2001 May; 14(5):476-82. PubMed ID: 11368544
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Excretion of food-derived heterocyclic amine carcinogens into breast milk of lactating rats and formation of DNA adducts in the newborn.
    Ghoshal A; Snyderwine EG
    Carcinogenesis; 1993 Nov; 14(11):2199-203. PubMed ID: 8242844
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Molecular dosimetry of the food-borne carcinogen MeIQx using adducts of serum albumin.
    Lynch AM; Murray S; Zhao K; Gooderham NJ; Boobis AR; Davies DS
    Carcinogenesis; 1993 Feb; 14(2):191-4. PubMed ID: 8435859
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Metabolism of carcinogenic heterocyclic and aromatic amines by recombinant human cytochrome P450 enzymes.
    Hammons GJ; Milton D; Stepps K; Guengerich FP; Tukey RH; Kadlubar FF
    Carcinogenesis; 1997 Apr; 18(4):851-4. PubMed ID: 9111224
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cytochrome P450 forms in the rodent lung involved in the metabolic activation of food-derived heterocyclic amines.
    Hellmold H; Overvik E; Strömstedt M; Gustafsson JA
    Carcinogenesis; 1993 Sep; 14(9):1751-7. PubMed ID: 8403195
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Metabolism of the food carcinogen 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in isolated rat liver cells.
    Wallin H; Holme JA; Becher G; Alexander J
    Carcinogenesis; 1989 Jul; 10(7):1277-83. PubMed ID: 2736718
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.