BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

509 related articles for article (PubMed ID: 22118460)

  • 1. The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation.
    Fischer ES; Scrima A; Böhm K; Matsumoto S; Lingaraju GM; Faty M; Yasuda T; Cavadini S; Wakasugi M; Hanaoka F; Iwai S; Gut H; Sugasawa K; Thomä NH
    Cell; 2011 Nov; 147(5):1024-39. PubMed ID: 22118460
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Detecting UV-lesions in the genome: The modular CRL4 ubiquitin ligase does it best!
    Scrima A; Fischer ES; Lingaraju GM; Böhm K; Cavadini S; Thomä NH
    FEBS Lett; 2011 Sep; 585(18):2818-25. PubMed ID: 21550341
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome.
    Cavadini S; Fischer ES; Bunker RD; Potenza A; Lingaraju GM; Goldie KN; Mohamed WI; Faty M; Petzold G; Beckwith RE; Tichkule RB; Hassiepen U; Abdulrahman W; Pantelic RS; Matsumoto S; Sugasawa K; Stahlberg H; Thomä NH
    Nature; 2016 Mar; 531(7596):598-603. PubMed ID: 27029275
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A.
    Guerrero-Santoro J; Kapetanaki MG; Hsieh CL; Gorbachinsky I; Levine AS; Rapić-Otrin V
    Cancer Res; 2008 Jul; 68(13):5014-22. PubMed ID: 18593899
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites.
    Kapetanaki MG; Guerrero-Santoro J; Bisi DC; Hsieh CL; Rapić-Otrin V; Levine AS
    Proc Natl Acad Sci U S A; 2006 Feb; 103(8):2588-93. PubMed ID: 16473935
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DNA-binding and cullin 4A ubiquitin ligase activity.
    Li J; Wang QE; Zhu Q; El-Mahdy MA; Wani G; Praetorius-Ibba M; Wani AA
    Cancer Res; 2006 Sep; 66(17):8590-7. PubMed ID: 16951172
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage.
    Groisman R; Polanowska J; Kuraoka I; Sawada J; Saijo M; Drapkin R; Kisselev AF; Tanaka K; Nakatani Y
    Cell; 2003 May; 113(3):357-67. PubMed ID: 12732143
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Monoubiquitinated histone H2A destabilizes photolesion-containing nucleosomes with concomitant release of UV-damaged DNA-binding protein E3 ligase.
    Lan L; Nakajima S; Kapetanaki MG; Hsieh CL; Fagerburg M; Thickman K; Rodriguez-Collazo P; Leuba SH; Levine AS; Rapić-Otrin V
    J Biol Chem; 2012 Apr; 287(15):12036-49. PubMed ID: 22334663
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery.
    Angers S; Li T; Yi X; MacCoss MJ; Moon RT; Zheng N
    Nature; 2006 Oct; 443(7111):590-3. PubMed ID: 16964240
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The CRL4
    Mohamed WI; Schenk AD; Kempf G; Cavadini S; Basters A; Potenza A; Abdul Rahman W; Rabl J; Reichermeier K; Thomä NH
    EMBO J; 2021 Nov; 40(22):e108008. PubMed ID: 34595758
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autophagic UVRAG Promotes UV-Induced Photolesion Repair by Activation of the CRL4(DDB2) E3 Ligase.
    Yang Y; He S; Wang Q; Li F; Kwak MJ; Chen S; O'Connell D; Zhang T; Pirooz SD; Jeon YH; Chimge NO; Frenkel B; Choi Y; Aldrovandi GM; Oh BH; Yuan Z; Liang C
    Mol Cell; 2016 May; 62(4):507-19. PubMed ID: 27203177
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human CRL4
    Zhu Q; Wei S; Sharma N; Wani G; He J; Wani AA
    Oncotarget; 2017 Nov; 8(61):104525-104542. PubMed ID: 29262658
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex.
    Wick ET; Treadway CJ; Li Z; Nicely NI; Ren Z; Baldwin AS; Xiong Y; Harrison JS; Brown NG
    J Virol; 2022 Sep; 96(17):e0082622. PubMed ID: 35938868
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.
    Takedachi A; Saijo M; Tanaka K
    Mol Cell Biol; 2010 Jun; 30(11):2708-23. PubMed ID: 20368362
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DDB2, the xeroderma pigmentosum group E gene product, is directly ubiquitylated by Cullin 4A-based ubiquitin ligase complex.
    Matsuda N; Azuma K; Saijo M; Iemura S; Hioki Y; Natsume T; Chiba T; Tanaka K; Tanaka K
    DNA Repair (Amst); 2005 May; 4(5):537-45. PubMed ID: 15811626
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Damage-specific DNA binding protein 1 (DDB1): a protein with a wide range of functions.
    Iovine B; Iannella ML; Bevilacqua MA
    Int J Biochem Cell Biol; 2011 Dec; 43(12):1664-7. PubMed ID: 21959250
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.
    Luijsterburg MS; Goedhart J; Moser J; Kool H; Geverts B; Houtsmuller AB; Mullenders LH; Vermeulen W; van Driel R
    J Cell Sci; 2007 Aug; 120(Pt 15):2706-16. PubMed ID: 17635991
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases.
    Olma MH; Roy M; Le Bihan T; Sumara I; Maerki S; Larsen B; Quadroni M; Peter M; Tyers M; Pintard L
    J Cell Sci; 2009 Apr; 122(Pt 7):1035-44. PubMed ID: 19295130
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair.
    Yeh JI; Levine AS; Du S; Chinte U; Ghodke H; Wang H; Shi H; Hsieh CL; Conway JF; Van Houten B; Rapić-Otrin V
    Proc Natl Acad Sci U S A; 2012 Oct; 109(41):E2737-46. PubMed ID: 22822215
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.
    Scrima A; Konícková R; Czyzewski BK; Kawasaki Y; Jeffrey PD; Groisman R; Nakatani Y; Iwai S; Pavletich NP; Thomä NH
    Cell; 2008 Dec; 135(7):1213-23. PubMed ID: 19109893
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.