166 related articles for article (PubMed ID: 22118829)
1. Structure based drug design, synthesis and evaluation of 4-(benzyloxy)-1-phenylbut-2-yn-1-ol derivatives as 5-lipoxygenase inhibitors.
Reddy NP; Chandramohan Reddy T; Aparoy P; Achari C; Sridhar PR; Reddanna P
Eur J Med Chem; 2012 Jan; 47(1):351-9. PubMed ID: 22118829
[TBL] [Abstract][Full Text] [Related]
2. Design, synthesis, and biological evaluation of prenylated chalcones as 5-LOX inhibitors.
Reddy NP; Aparoy P; Reddy TC; Achari C; Sridhar PR; Reddanna P
Bioorg Med Chem; 2010 Aug; 18(16):5807-15. PubMed ID: 20667741
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
Rao PN; Chen QH; Knaus EE
J Med Chem; 2006 Mar; 49(5):1668-83. PubMed ID: 16509583
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of benzoxazole derivatives as 5-lipoxygenase inhibitors.
Song H; Oh SR; Lee HK; Han G; Kim JH; Chang HW; Doh KE; Rhee HK; Choo HY
Bioorg Med Chem; 2010 Nov; 18(21):7580-5. PubMed ID: 20870413
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
Tan CM; Chen GS; Chen CS; Chang PT; Chern JW
Bioorg Med Chem; 2011 Nov; 19(21):6316-28. PubMed ID: 21958737
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of N-aryl-4-aryl-1,3-thiazole-2-amine derivatives as direct 5-lipoxygenase inhibitors.
Suh J; Yum EK; Cheon HG; Cho YS
Chem Biol Drug Des; 2012 Jul; 80(1):89-98. PubMed ID: 22404847
[TBL] [Abstract][Full Text] [Related]
7. Bioassay-guided identification of an anti-inflammatory prenylated acylphloroglucinol from Melicope ptelefolia and molecular insights into its interaction with 5-lipoxygenase.
Shaari K; Suppaiah V; Wai LK; Stanslas J; Tejo BA; Israf DA; Abas F; Ismail IS; Shuaib NH; Zareen S; Lajis NH
Bioorg Med Chem; 2011 Nov; 19(21):6340-7. PubMed ID: 21958738
[TBL] [Abstract][Full Text] [Related]
8. Synthesis of new sulfonamides as lipoxygenase inhibitors.
Mustafa G; Khan IU; Ashraf M; Afzal I; Shahzad SA; Shafiq M
Bioorg Med Chem; 2012 Apr; 20(8):2535-9. PubMed ID: 22436389
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and SAR study of 4,5-diaryl-1H-imidazole-2(3H)-thione derivatives, as potent 15-lipoxygenase inhibitors.
Assadieskandar A; Amini M; Salehi M; Sadeghian H; Alimardani M; Sakhteman A; Nadri H; Shafiee A
Bioorg Med Chem; 2012 Dec; 20(24):7160-6. PubMed ID: 23117172
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of 3-[4-(amino/methylsulfonyl)phenyl]methylene-indolin-2-one derivatives as novel COX-1/2 and 5-LOX inhibitors.
Lai Y; Ma L; Huang W; Yu X; Zhang Y; Ji H; Tian J
Bioorg Med Chem Lett; 2010 Dec; 20(24):7349-53. PubMed ID: 21055929
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and biochemical evaluation of benzyl propargyl ethers as inhibitors of 5-lipoxygenase.
Barhate NB; Reddy MC; Reddy PS; Wakharkar RD; Reddanna P
Indian J Biochem Biophys; 2002 Aug; 39(4):264-73. PubMed ID: 22908417
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of a new class of acyl derivatives of 3-amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one as potential dual cyclooxygenase (COX-1 and COX-2) and human lipoxygenase (5-LOX) inhibitors.
Cusan C; Spalluto G; Prato M; Adams M; Bodensieck A; Bauer R; Tubaro A; Bernardi P; Da Ros T
Farmaco; 2005 Apr; 60(4):327-32. PubMed ID: 15848208
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological evaluation of a class of 5-benzylidene-2-phenyl-thiazolinones as potent 5-lipoxygenase inhibitors.
Barzen S; Rödl CB; Lill A; Steinhilber D; Stark H; Hofmann B
Bioorg Med Chem; 2012 Jun; 20(11):3575-83. PubMed ID: 22551629
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis and evaluation of novel diaryl-1,5-diazoles derivatives bearing morpholine as potent dual COX-2/5-LOX inhibitors and antitumor agents.
Li Z; Wang ZC; Li X; Abbas M; Wu SY; Ren SZ; Liu QX; Liu Y; Chen PW; Duan YT; Lv PC; Zhu HL
Eur J Med Chem; 2019 May; 169():168-184. PubMed ID: 30877972
[TBL] [Abstract][Full Text] [Related]
15. Pharmacophore modeling and virtual screening for designing potential 5-lipoxygenase inhibitors.
Aparoy P; Kumar Reddy K; Kalangi SK; Chandramohan Reddy T; Reddanna P
Bioorg Med Chem Lett; 2010 Feb; 20(3):1013-8. PubMed ID: 20045317
[TBL] [Abstract][Full Text] [Related]
16. Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX.
Shen FQ; Wang ZC; Wu SY; Ren SZ; Man RJ; Wang BZ; Zhu HL
Bioorg Med Chem Lett; 2017 Aug; 27(16):3653-3660. PubMed ID: 28720504
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of conformationally constrained aci-reductone mimics of arachidonic acid.
Hopper AT; Witiak DT; Ziemniak J
J Med Chem; 1998 Feb; 41(4):420-7. PubMed ID: 9484493
[TBL] [Abstract][Full Text] [Related]
18. Potent inhibitors of 5-lipoxygenase identified using pseudoreceptors.
Rödl CB; Tanrikulu Y; Wisniewska JM; Proschak E; Schneider G; Steinhilber D; Hofmann B
ChemMedChem; 2011 Jun; 6(6):1001-5. PubMed ID: 21506275
[No Abstract] [Full Text] [Related]
19. Synthesis and biological evaluation of 1,3-diphenylprop-2-yn-1-ones as dual inhibitors of cyclooxygenases and lipoxygenases.
Rao PN; Chen QH; Knaus EE
Bioorg Med Chem Lett; 2005 Nov; 15(21):4842-5. PubMed ID: 16143531
[TBL] [Abstract][Full Text] [Related]
20. Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model.
Melstrom LG; Bentrem DJ; Salabat MR; Kennedy TJ; Ding XZ; Strouch M; Rao SM; Witt RC; Ternent CA; Talamonti MS; Bell RH; Adrian TA
Clin Cancer Res; 2008 Oct; 14(20):6525-30. PubMed ID: 18927292
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
