BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

239 related articles for article (PubMed ID: 22120039)

  • 1. Aberrant epigenetic regulation of bromodomain BRD4 in human colon cancer.
    Rodriguez RM; Huidobro C; Urdinguio RG; Mangas C; Soldevilla B; Domínguez G; Bonilla F; Fernandez AF; Fraga MF
    J Mol Med (Berl); 2012 May; 90(5):587-95. PubMed ID: 22120039
    [TBL] [Abstract][Full Text] [Related]  

  • 2. BRD4 promotes gastric cancer progression through the transcriptional and epigenetic regulation of c-MYC.
    Ba M; Long H; Yan Z; Wang S; Wu Y; Tu Y; Gong Y; Cui S
    J Cell Biochem; 2018 Jan; 119(1):973-982. PubMed ID: 28681984
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
    Zuber J; Shi J; Wang E; Rappaport AR; Herrmann H; Sison EA; Magoon D; Qi J; Blatt K; Wunderlich M; Taylor MJ; Johns C; Chicas A; Mulloy JC; Kogan SC; Brown P; Valent P; Bradner JE; Lowe SW; Vakoc CR
    Nature; 2011 Aug; 478(7370):524-8. PubMed ID: 21814200
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1.
    Zhang C; Su ZY; Wang L; Shu L; Yang Y; Guo Y; Pung D; Bountra C; Kong AN
    Biochem Pharmacol; 2016 Oct; 117():35-45. PubMed ID: 27520485
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disruption of BRD4 at H3K27Ac-enriched enhancer region correlates with decreased c-Myc expression in Merkel cell carcinoma.
    Sengupta D; Kannan A; Kern M; Moreno MA; Vural E; Stack B; Suen JY; Tackett AJ; Gao L
    Epigenetics; 2015; 10(6):460-6. PubMed ID: 25941994
    [TBL] [Abstract][Full Text] [Related]  

  • 6. H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription.
    Nagarajan S; Benito E; Fischer A; Johnsen SA
    Oncotarget; 2015 Mar; 6(9):7305-17. PubMed ID: 25788266
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of BRD4 suppresses tumor growth in prostate cancer via the enhancement of FOXO1 expression.
    Tan Y; Wang L; Du Y; Liu X; Chen Z; Weng X; Guo J; Chen H; Wang M; Wang X
    Int J Oncol; 2018 Dec; 53(6):2503-2517. PubMed ID: 30272279
    [TBL] [Abstract][Full Text] [Related]  

  • 8. BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail.
    Qin ZY; Wang T; Su S; Shen LT; Zhu GX; Liu Q; Zhang L; Liu KW; Zhang Y; Zhou ZH; Zhang XN; Wen LZ; Yao YL; Sun WJ; Guo Y; Liu KJ; Liu L; Wang XW; Wei YL; Wang J; Xiao HL; Liu P; Bian XW; Chen DF; Wang B
    Cancer Res; 2019 Oct; 79(19):4869-4881. PubMed ID: 31311807
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation.
    Rahnamoun H; Lee J; Sun Z; Lu H; Ramsey KM; Komives EA; Lauberth SM
    Nat Struct Mol Biol; 2018 Aug; 25(8):687-697. PubMed ID: 30076409
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer.
    Shi J; Wang Y; Zeng L; Wu Y; Deng J; Zhang Q; Lin Y; Li J; Kang T; Tao M; Rusinova E; Zhang G; Wang C; Zhu H; Yao J; Zeng YX; Evers BM; Zhou MM; Zhou BP
    Cancer Cell; 2014 Feb; 25(2):210-25. PubMed ID: 24525235
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Epigenetic control of HNF-4α in colon carcinoma cells affects MUC4 expression and malignancy.
    Algamas-Dimantov A; Yehuda-Shnaidman E; Peri I; Schwartz B
    Cell Oncol (Dordr); 2013 Apr; 36(2):155-67. PubMed ID: 23307400
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MPP3 inactivation by promoter CpG islands hypermethylation in colorectal carcinogenesis.
    Feng X; Chen K; Ye S; Wang H; Wei G; Tan W; Cheng S; Zhang Y; Liu S; Zhou Y
    Cancer Biomark; 2012; 11(2-3):99-106. PubMed ID: 23011156
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells.
    Zhang W; Prakash C; Sum C; Gong Y; Li Y; Kwok JJ; Thiessen N; Pettersson S; Jones SJ; Knapp S; Yang H; Chin KC
    J Biol Chem; 2012 Dec; 287(51):43137-55. PubMed ID: 23086925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interfering with bromodomain epigenome readers as therapeutic option in mucoepidermoid carcinoma.
    Markman RL; Webber LP; Nascimento Filho CHV; Reis LA; Vargas PA; Lopes MA; Zanella V; Martins MD; Squarize CH; Castilho RM
    Cell Oncol (Dordr); 2019 Apr; 42(2):143-155. PubMed ID: 30539410
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Epigenetic inactivation of T-box transcription factor 5, a novel tumor suppressor gene, is associated with colon cancer.
    Yu J; Ma X; Cheung KF; Li X; Tian L; Wang S; Wu CW; Wu WK; He M; Wang M; Ng SS; Sung JJ
    Oncogene; 2010 Dec; 29(49):6464-74. PubMed ID: 20802524
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BRD4 Promotes DNA Repair and Mediates the Formation of TMPRSS2-ERG Gene Rearrangements in Prostate Cancer.
    Li X; Baek G; Ramanand SG; Sharp A; Gao Y; Yuan W; Welti J; Rodrigues DN; Dolling D; Figueiredo I; Sumanasuriya S; Crespo M; Aslam A; Li R; Yin Y; Mukherjee B; Kanchwala M; Hughes AM; Halsey WS; Chiang CM; Xing C; Raj GV; Burma S; de Bono J; Mani RS
    Cell Rep; 2018 Jan; 22(3):796-808. PubMed ID: 29346775
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation.
    Pastori C; Kapranov P; Penas C; Peschansky V; Volmar CH; Sarkaria JN; Bregy A; Komotar R; St Laurent G; Ayad NG; Wahlestedt C
    Proc Natl Acad Sci U S A; 2015 Jul; 112(27):8326-31. PubMed ID: 26111795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing.
    Ferres-Marco D; Gutierrez-Garcia I; Vallejo DM; Bolivar J; Gutierrez-Aviño FJ; Dominguez M
    Nature; 2006 Jan; 439(7075):430-6. PubMed ID: 16437107
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional interdependence of BRD4 and DOT1L in MLL leukemia.
    Gilan O; Lam EY; Becher I; Lugo D; Cannizzaro E; Joberty G; Ward A; Wiese M; Fong CY; Ftouni S; Tyler D; Stanley K; MacPherson L; Weng CF; Chan YC; Ghisi M; Smil D; Carpenter C; Brown P; Garton N; Blewitt ME; Bannister AJ; Kouzarides T; Huntly BJ; Johnstone RW; Drewes G; Dawson SJ; Arrowsmith CH; Grandi P; Prinjha RK; Dawson MA
    Nat Struct Mol Biol; 2016 Jul; 23(7):673-81. PubMed ID: 27294782
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting the BRD4-HOXB13 Coregulated Transcriptional Networks with Bromodomain-Kinase Inhibitors to Suppress Metastatic Castration-Resistant Prostate Cancer.
    Nerlakanti N; Yao J; Nguyen DT; Patel AK; Eroshkin AM; Lawrence HR; Ayaz M; Kuenzi BM; Agarwal N; Chen Y; Gunawan S; Karim RM; Berndt N; Puskas J; Magliocco AM; Coppola D; Dhillon J; Zhang J; Shymalagovindarajan S; Rix U; Kim Y; Perera R; Lawrence NJ; Schonbrunn E; Mahajan K
    Mol Cancer Ther; 2018 Dec; 17(12):2796-2810. PubMed ID: 30242092
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.