BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

368 related articles for article (PubMed ID: 22120593)

  • 1. Lysosomal vitamin E accumulation in Niemann-Pick type C disease.
    Yévenes LF; Klein A; Castro JF; Marín T; Leal N; Leighton F; Alvarez AR; Zanlungo S
    Biochim Biophys Acta; 2012 Feb; 1822(2):150-60. PubMed ID: 22120593
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Vitamin E dietary supplementation improves neurological symptoms and decreases c-Abl/p73 activation in Niemann-Pick C mice.
    Marín T; Contreras P; Castro JF; Chamorro D; Balboa E; Bosch-Morató M; Muñoz FJ; Alvarez AR; Zanlungo S
    Nutrients; 2014 Jul; 6(8):3000-17. PubMed ID: 25079853
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Altered vitamin E status in Niemann-Pick type C disease.
    Ulatowski L; Parker R; Davidson C; Yanjanin N; Kelley TJ; Corey D; Atkinson J; Porter F; Arai H; Walkley SU; Manor D
    J Lipid Res; 2011 Jul; 52(7):1400-10. PubMed ID: 21550990
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Beneficial effects of primidone in Niemann-Pick disease type C (NPC)-model cells and mice: Reduction of unesterified cholesterol levels in cells and extension of lifespan in mice.
    Ashikawa H; Mogi H; Honda T; Nakamura H; Murayama T
    Eur J Pharmacol; 2021 Apr; 896():173907. PubMed ID: 33503462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.
    Torres S; Matías N; Baulies A; Nuñez S; Alarcon-Vila C; Martinez L; Nuño N; Fernandez A; Caballeria J; Levade T; Gonzalez-Franquesa A; Garcia-Rovés P; Balboa E; Zanlungo S; Fabrías G; Casas J; Enrich C; Garcia-Ruiz C; Fernández-Checa JC
    Redox Biol; 2017 Apr; 11():60-72. PubMed ID: 27888692
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Niemann-Pick Disease Type C: from molecule to clinic.
    Tang Y; Li H; Liu JP
    Clin Exp Pharmacol Physiol; 2010 Jan; 37(1):132-40. PubMed ID: 19566836
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation.
    Dominko K; Rastija A; Sobocanec S; Vidatic L; Meglaj S; Lovincic Babic A; Hutter-Paier B; Colombo AV; Lichtenthaler SF; Tahirovic S; Hecimovic S
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948052
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Niemann-Pick C1 protein in recycling endosomes of presynaptic nerve terminals.
    Karten B; Campenot RB; Vance DE; Vance JE
    J Lipid Res; 2006 Mar; 47(3):504-14. PubMed ID: 16340014
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endosomal/lysosomal processing of gangliosides affects neuronal cholesterol sequestration in Niemann-Pick disease type C.
    Zhou S; Davidson C; McGlynn R; Stephney G; Dobrenis K; Vanier MT; Walkley SU
    Am J Pathol; 2011 Aug; 179(2):890-902. PubMed ID: 21708114
    [TBL] [Abstract][Full Text] [Related]  

  • 10. GCase and LIMP2 Abnormalities in the Liver of Niemann Pick Type C Mice.
    van der Lienden MJC; Aten J; Marques ARA; Waas ISE; Larsen PWB; Claessen N; van der Wel NN; Ottenhoff R; van Eijk M; Aerts JMFG
    Int J Mol Sci; 2021 Mar; 22(5):. PubMed ID: 33802460
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice.
    Peake KB; Vance JE
    J Biol Chem; 2012 Mar; 287(12):9290-8. PubMed ID: 22277650
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FTY720/fingolimod increases NPC1 and NPC2 expression and reduces cholesterol and sphingolipid accumulation in Niemann-Pick type C mutant fibroblasts.
    Newton J; Hait NC; Maceyka M; Colaco A; Maczis M; Wassif CA; Cougnoux A; Porter FD; Milstien S; Platt N; Platt FM; Spiegel S
    FASEB J; 2017 Apr; 31(4):1719-1730. PubMed ID: 28082351
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oxidative stress: a pathogenic mechanism for Niemann-Pick type C disease.
    Vázquez MC; Balboa E; Alvarez AR; Zanlungo S
    Oxid Med Cell Longev; 2012; 2012():205713. PubMed ID: 22720116
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brains.
    Kodam A; Maulik M; Peake K; Amritraj A; Vetrivel KS; Thinakaran G; Vance JE; Kar S
    Glia; 2010 Aug; 58(11):1267-81. PubMed ID: 20607864
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alteration of gene expression profile in Niemann-Pick type C mice correlates with tissue damage and oxidative stress.
    Vázquez MC; del Pozo T; Robledo FA; Carrasco G; Pavez L; Olivares F; González M; Zanlungo S
    PLoS One; 2011; 6(12):e28777. PubMed ID: 22216111
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Presymptomatic Alterations in Amino Acid Metabolism and DNA Methylation in the Cerebellum of a Murine Model of Niemann-Pick Type C Disease.
    Kennedy BE; Hundert AS; Goguen D; Weaver IC; Karten B
    Am J Pathol; 2016 Jun; 186(6):1582-97. PubMed ID: 27083515
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice.
    Amritraj A; Peake K; Kodam A; Salio C; Merighi A; Vance JE; Kar S
    Am J Pathol; 2009 Dec; 175(6):2540-56. PubMed ID: 19893049
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pre-symptomatic activation of antioxidant responses and alterations in glucose and pyruvate metabolism in Niemann-Pick Type C1-deficient murine brain.
    Kennedy BE; LeBlanc VG; Mailman TM; Fice D; Burton I; Karakach TK; Karten B
    PLoS One; 2013; 8(12):e82685. PubMed ID: 24367541
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
    Causevic M; Dominko K; Malnar M; Vidatic L; Cermak S; Pigoni M; Kuhn PH; Colombo A; Havas D; Flunkert S; McDonald J; Gunnersen JM; Hutter-Paier B; Tahirovic S; Windisch M; Krainc D; Lichtenthaler SF; Hecimovic S
    PLoS One; 2018; 13(7):e0200344. PubMed ID: 29979789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Finding pathogenic commonalities between Niemann-Pick type C and other lysosomal storage disorders: Opportunities for shared therapeutic interventions.
    Yañez MJ; Marín T; Balboa E; Klein AD; Alvarez AR; Zanlungo S
    Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165875. PubMed ID: 32522631
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.