BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 22121780)

  • 1. [Synthesis and biological evaluation of sorafenib thiourea derivatives].
    Yang Z; Fang Z; Wang ZX; Wei P
    Yao Xue Xue Bao; 2011 Sep; 46(9):1093-7. PubMed ID: 22121780
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis and biological activities of sorafenib derivatives as antitumor agents.
    Yao J; He Z; Chen J; Sun W; Fang H; Xu W
    Bioorg Med Chem Lett; 2012 Nov; 22(21):6549-53. PubMed ID: 23021967
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Design, synthesis and antitumor activity of sorafenib analogues containing 2-picolinylhydrazide moiety].
    Qin AF; Li Y; Song HR; Chen XG; Jin XF; Wang K; Zhang LJ; Huo LC; Feng ZQ
    Yao Xue Xue Bao; 2012 Dec; 47(12):1623-9. PubMed ID: 23460968
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Synthesis and in vitro cytotoxic activities of sorafenib derivatives].
    Wang K; Li Y; Zhang LJ; Yang HZ; Chen XG; Feng ZQ
    Yao Xue Xue Bao; 2014 May; 49(5):639-43. PubMed ID: 25151734
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and in vitro antitumor activities of novel benzyl urea analogues of sorafenib.
    Lu CS; Tang K; Li Y; Jin B; Yin DL; Ma C; Chen XG; Huang HH
    Yao Xue Xue Bao; 2013 May; 48(5):709-17. PubMed ID: 23888694
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and evaluation of novel 2-(1H-imidazol-2-yl) pyridine Sorafenib derivatives as potential BRAF inhibitors and anti-tumor agents.
    Jiao Y; Xin BT; Zhang Y; Wu J; Lu X; Zheng Y; Tang W; Zhou X
    Eur J Med Chem; 2015 Jan; 90():170-83. PubMed ID: 25461318
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and antitumor activity of Novel Sorafenib derivatives bearing pyrazole scaffold.
    Wang M; Xu S; Lei H; Wang C; Xiao Z; Jia S; Zhi J; Zheng P; Zhu W
    Bioorg Med Chem; 2017 Oct; 25(20):5754-5763. PubMed ID: 28927801
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and activity of novel sorafenib analogues bearing chalcone unit.
    Wang M; Xu S; Wu C; Liu X; Tao H; Huang Y; Liu Y; Zheng P; Zhu W
    Bioorg Med Chem Lett; 2016 Nov; 26(22):5450-5454. PubMed ID: 27777009
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, activity and docking studies of phenylpyrimidine-carboxamide Sorafenib derivatives.
    Wang W; Wu C; Wang J; Luo R; Wang C; Liu X; Li J; Zhu W; Zheng P
    Bioorg Med Chem; 2016 Dec; 24(23):6166-6173. PubMed ID: 28340913
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and structure-activity relationships of N-benzyl-N-(X-2-hydroxybenzyl)-N'-phenylureas and thioureas as antitumor agents.
    Li HQ; Yan T; Yang Y; Shi L; Zhou CF; Zhu HL
    Bioorg Med Chem; 2010 Jan; 18(1):305-13. PubMed ID: 19914837
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Advances in the study of structural modifications of multi-target anticancer drug sorafenib].
    Yao JW; Sun W; Chen J; Xu WF
    Yao Xue Xue Bao; 2012 Sep; 47(9):1111-9. PubMed ID: 23227538
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis, Biological Evaluation and Docking Studies of Sorafenib Derivatives N-(3-fluoro-4-(pyridin-4-yloxy)phenyl)-4(5)-phenylpicolinamides.
    Wang M; Wu C; Xu S; Zhu Y; Li W; Zheng P; Zhu W
    Med Chem; 2017; 13(2):176-185. PubMed ID: 27855595
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, Synthesis, Activity and Docking Study of Sorafenib Analogs Bearing Sulfonylurea Unit.
    Wu C; Wang M; Tang Q; Luo R; Chen L; Zheng P; Zhu W
    Molecules; 2015 Oct; 20(10):19361-71. PubMed ID: 26512636
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and Preliminary Cytotoxicity Studies of 1-[1-(4,5-Dihydrooxazol- 2-yl)-1H-indazol-3-yl]-3-phenylurea and 3-phenylthiourea Derivatives.
    Kornicka A; Saczewski F; Bednarski PJ; Korcz M; Szumlas P; Romejko E; Sakowicz A; Sitek L; Wojciechowska M
    Med Chem; 2017; 13(7):616-624. PubMed ID: 28266278
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives.
    Li J; Tan JZ; Chen LL; Zhang J; Shen X; Mei CL; Fu LL; Lin LP; Ding J; Xiong B; Xiong XS; Liu H; Luo XM; Jiang HL
    Acta Pharmacol Sin; 2006 Sep; 27(9):1259-71. PubMed ID: 16923349
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Synthesis and biological evaluation of 3-aromatic Shiff base-5-fluoroindol-2-one derivatives].
    Fang Z; Yang Z; Xu JF; Wang YL; Wang ZX; Wei P
    Yao Xue Xue Bao; 2011 Nov; 46(11):1338-43. PubMed ID: 22260025
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sorafenib derivatives induce apoptosis through inhibition of STAT3 independent of Raf.
    Chen KF; Tai WT; Huang JW; Hsu CY; Chen WL; Cheng AL; Chen PJ; Shiau CW
    Eur J Med Chem; 2011 Jul; 46(7):2845-51. PubMed ID: 21531053
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and SAR studies of urea and thiourea derivatives of gly/pro conjugated to piperazine analogue as potential AGE inhibitors.
    Vardhan DM; Shantharam CS; Suhas R; Sridhara MB; Gowda DC
    Protein Pept Lett; 2013 Aug; 20(8):888-97. PubMed ID: 23331128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biological Validation of Novel Polysubstituted Pyrazole Candidates with in Vitro Anticancer Activities.
    Fahmy HH; Khalifa NM; Ismail MM; El-Sahrawy HM; Nossier ES
    Molecules; 2016 Feb; 21(3):271. PubMed ID: 26927048
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological activities of thiourea containing sorafenib analogs as antitumor agents.
    Yao J; Chen J; He Z; Sun W; Xu W
    Bioorg Med Chem; 2012 May; 20(9):2923-9. PubMed ID: 22483592
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.