BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

318 related articles for article (PubMed ID: 22122056)

  • 1. γ-Secretase inhibitors and modulators for Alzheimer's disease.
    Wolfe MS
    J Neurochem; 2012 Jan; 120 Suppl 1(Suppl 1):89-98. PubMed ID: 22122056
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Selective amyloid-beta lowering agents.
    Wolfe MS
    BMC Neurosci; 2008 Dec; 9 Suppl 2(Suppl 2):S4. PubMed ID: 19090992
    [TBL] [Abstract][Full Text] [Related]  

  • 3. gamma-Secretase as a therapeutic target in Alzheimer's disease.
    Guardia-Laguarta C; Pera M; Lleó A
    Curr Drug Targets; 2010 Apr; 11(4):506-17. PubMed ID: 20015011
    [TBL] [Abstract][Full Text] [Related]  

  • 4. γ-Secretase and its modulators: Twenty years and beyond.
    Xia W
    Neurosci Lett; 2019 May; 701():162-169. PubMed ID: 30763650
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease.
    De Strooper B; Iwatsubo T; Wolfe MS
    Cold Spring Harb Perspect Med; 2012 Jan; 2(1):a006304. PubMed ID: 22315713
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Secretase inhibitors and modulators for Alzheimer's disease treatment.
    Tomita T
    Expert Rev Neurother; 2009 May; 9(5):661-79. PubMed ID: 19402777
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protease inhibitors as potential disease-modifying therapeutics for Alzheimer's disease.
    Beher D; Graham SL
    Expert Opin Investig Drugs; 2005 Nov; 14(11):1385-409. PubMed ID: 16255678
    [TBL] [Abstract][Full Text] [Related]  

  • 8. γ-Secretase inhibitors and modulators.
    Golde TE; Koo EH; Felsenstein KM; Osborne BA; Miele L
    Biochim Biophys Acta; 2013 Dec; 1828(12):2898-907. PubMed ID: 23791707
    [TBL] [Abstract][Full Text] [Related]  

  • 9. γ-Secretase as a target for Alzheimer's disease.
    Wolfe MS
    Adv Pharmacol; 2012; 64():127-53. PubMed ID: 22840746
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Probing Mechanisms and Therapeutic Potential of γ-Secretase in Alzheimer's Disease.
    Wolfe MS
    Molecules; 2021 Jan; 26(2):. PubMed ID: 33450968
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Secretase as a target for Alzheimer's disease.
    Wolfe MS
    Curr Top Med Chem; 2002 Apr; 2(4):371-83. PubMed ID: 11966461
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition and modulation of gamma-secretase for Alzheimer's disease.
    Wolfe MS
    Neurotherapeutics; 2008 Jul; 5(3):391-8. PubMed ID: 18625450
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure, mechanism and inhibition of gamma-secretase and presenilin-like proteases.
    Wolfe MS
    Biol Chem; 2010 Aug; 391(8):839-47. PubMed ID: 20482315
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vivo manifestation of Notch related phenotypes in zebrafish treated with Alzheimer's amyloid reducing gamma-secretase inhibitors.
    Yang T; Arslanova D; Xu X; Li YM; Xia W
    J Neurochem; 2010 Jun; 113(5):1200-9. PubMed ID: 20345767
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of notch-sparing gamma-secretase inhibitors.
    Augelli-Szafran CE; Wei HX; Lu D; Zhang J; Gu Y; Yang T; Osenkowski P; Ye W; Wolfe MS
    Curr Alzheimer Res; 2010 May; 7(3):207-9. PubMed ID: 20088802
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of gamma-secretase as a therapeutic intervention for Alzheimer's disease: prospects, limitations and strategies.
    Evin G; Sernee MF; Masters CL
    CNS Drugs; 2006; 20(5):351-72. PubMed ID: 16696577
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Recent advances in the identification of gamma-secretase inhibitors to clinically test the Abeta oligomer hypothesis of Alzheimer's disease.
    Kreft AF; Martone R; Porte A
    J Med Chem; 2009 Oct; 52(20):6169-88. PubMed ID: 19694467
    [No Abstract]   [Full Text] [Related]  

  • 18. Secretase inhibitors for Alzheimer's disease: challenges of a promiscuous protease.
    Pollack SJ; Lewis H
    Curr Opin Investig Drugs; 2005 Jan; 6(1):35-47. PubMed ID: 15675602
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insight γ-Secretase: Structure, Function, and Role in Alzheimer's Disease.
    Mal S; Malik U; Pal D; Mishra A
    Curr Drug Targets; 2021; 22(12):1376-1403. PubMed ID: 33390127
    [TBL] [Abstract][Full Text] [Related]  

  • 20. γ-Secretase in Alzheimer's disease.
    Hur JY
    Exp Mol Med; 2022 Apr; 54(4):433-446. PubMed ID: 35396575
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.