These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 22122349)

  • 1. Regulation of β-site APP-cleaving enzyme 1 gene expression and its role in Alzheimer's disease.
    Sun X; Bromley-Brits K; Song W
    J Neurochem; 2012 Jan; 120 Suppl 1():62-70. PubMed ID: 22122349
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes.
    Ly PT; Wu Y; Zou H; Wang R; Zhou W; Kinoshita A; Zhang M; Yang Y; Cai F; Woodgett J; Song W
    J Clin Invest; 2013 Jan; 123(1):224-35. PubMed ID: 23202730
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis.
    Zhao J; Fu Y; Yasvoina M; Shao P; Hitt B; O'Connor T; Logan S; Maus E; Citron M; Berry R; Binder L; Vassar R
    J Neurosci; 2007 Apr; 27(14):3639-49. PubMed ID: 17409228
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes.
    Sun X; Wang Y; Qing H; Christensen MA; Liu Y; Zhou W; Tong Y; Xiao C; Huang Y; Zhang S; Liu X; Song W
    FASEB J; 2005 May; 19(7):739-49. PubMed ID: 15857888
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 6. BAG-1M co-activates BACE1 transcription through NF-κB and accelerates Aβ production and memory deficit in Alzheimer's disease mouse model.
    Shi Z; Hong Y; Zhang K; Wang J; Zheng L; Zhang Z; Hu Z; Han X; Han Y; Chen T; Yao Q; Cui H; Hong W
    Biochim Biophys Acta Mol Basis Dis; 2017 Sep; 1863(9):2398-2407. PubMed ID: 28502705
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BACE1 gene promoter single-nucleotide polymorphisms in Alzheimer's disease.
    Zhou W; Cai F; Li Y; Yang GS; O'Connor KD; Holt RA; Song W
    J Mol Neurosci; 2010 Sep; 42(1):127-33. PubMed ID: 20455082
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and biology of β-secretase.
    Kandalepas PC; Vassar R
    J Neurochem; 2012 Jan; 120 Suppl 1():55-61. PubMed ID: 22122287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Splice variants of the Alzheimer's disease beta-secretase, BACE1.
    Holsinger RM; Goense N; Bohorquez J; Strappe P
    Neurogenetics; 2013 Feb; 14(1):1-9. PubMed ID: 23142975
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BACE1: the beta-secretase enzyme in Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.
    Rossner S; Sastre M; Bourne K; Lichtenthaler SF
    Prog Neurobiol; 2006 Jun; 79(2):95-111. PubMed ID: 16904810
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BACE1 structure and function in health and Alzheimer's disease.
    Cole SL; Vassar R
    Curr Alzheimer Res; 2008 Apr; 5(2):100-20. PubMed ID: 18393796
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased NF-κB signalling up-regulates BACE1 expression and its therapeutic potential in Alzheimer's disease.
    Chen CH; Zhou W; Liu S; Deng Y; Cai F; Tone M; Tone Y; Tong Y; Song W
    Int J Neuropsychopharmacol; 2012 Feb; 15(1):77-90. PubMed ID: 21329555
    [TBL] [Abstract][Full Text] [Related]  

  • 15. miR-186 is decreased in aged brain and suppresses BACE1 expression.
    Kim J; Yoon H; Chung DE; Brown JL; Belmonte KC; Kim J
    J Neurochem; 2016 May; 137(3):436-45. PubMed ID: 26710318
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects.
    Long JM; Ray B; Lahiri DK
    J Biol Chem; 2014 Feb; 289(8):5184-98. PubMed ID: 24352696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease.
    Sadleir KR; Kandalepas PC; Buggia-Prévot V; Nicholson DA; Thinakaran G; Vassar R
    Acta Neuropathol; 2016 Aug; 132(2):235-256. PubMed ID: 26993139
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression.
    Sun X; He G; Qing H; Zhou W; Dobie F; Cai F; Staufenbiel M; Huang LE; Song W
    Proc Natl Acad Sci U S A; 2006 Dec; 103(49):18727-32. PubMed ID: 17121991
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rheb GTPase regulates β-secretase levels and amyloid β generation.
    Shahani N; Pryor W; Swarnkar S; Kholodilov N; Thinakaran G; Burke RE; Subramaniam S
    J Biol Chem; 2014 Feb; 289(9):5799-808. PubMed ID: 24368770
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alzheimer's disease.
    De-Paula VJ; Radanovic M; Diniz BS; Forlenza OV
    Subcell Biochem; 2012; 65():329-52. PubMed ID: 23225010
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.