These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 22124116)

  • 1. hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: a possible mechanism for long QT syndrome.
    Trudeau MC; Leung LM; Roti ER; Robertson GA
    J Gen Physiol; 2011 Dec; 138(6):581-92. PubMed ID: 22124116
    [TBL] [Abstract][Full Text] [Related]  

  • 2. hERG1a and hERG1b potassium channel subunits directly interact and preferentially form heteromeric channels.
    McNally BA; Pendon ZD; Trudeau MC
    J Biol Chem; 2017 Dec; 292(52):21548-21557. PubMed ID: 29089383
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The N-linker region of hERG1a upregulates hERG1b potassium channels.
    Johnson AA; Crawford TR; Trudeau MC
    J Biol Chem; 2022 Sep; 298(9):102233. PubMed ID: 35798139
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels.
    Gianulis EC; Trudeau MC
    J Biol Chem; 2011 Jun; 286(25):22160-9. PubMed ID: 21536673
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels.
    Gustina AS; Trudeau MC
    Proc Natl Acad Sci U S A; 2009 Aug; 106(31):13082-7. PubMed ID: 19651618
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Isoform-specific dominant-negative effects associated with hERG1 G628S mutation in long QT syndrome.
    Stump MR; Gong Q; Zhou Z
    PLoS One; 2012; 7(8):e42552. PubMed ID: 22876326
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study.
    Perissinotti LL; De Biase PM; Guo J; Yang PC; Lee MC; Clancy CE; Duff HJ; Noskov SY
    Front Physiol; 2018; 9():207. PubMed ID: 29706893
    [TBL] [Abstract][Full Text] [Related]  

  • 8. hERG potassium channel gating is mediated by N- and C-terminal region interactions.
    Gustina AS; Trudeau MC
    J Gen Physiol; 2011 Mar; 137(3):315-25. PubMed ID: 21357734
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
    Liu QN; Trudeau MC
    PLoS One; 2015; 10(4):e0123951. PubMed ID: 25923442
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.
    Gianulis EC; Liu Q; Trudeau MC
    J Gen Physiol; 2013 Oct; 142(4):351-66. PubMed ID: 24043860
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced inhibitory effect of acidosis on hERG potassium channels that incorporate the hERG1b isoform.
    Du CY; El Harchi A; McPate MJ; Orchard CH; Hancox JC
    Biochem Biophys Res Commun; 2011 Feb; 405(2):222-7. PubMed ID: 21219869
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.
    Larsen AP; Olesen SP; Grunnet M; Jespersen T
    Pflugers Arch; 2008 Sep; 456(6):1137-48. PubMed ID: 18504605
    [TBL] [Abstract][Full Text] [Related]  

  • 13. hERG1a/1b heteromeric currents exhibit amplified attenuation of inactivation in variant 1 short QT syndrome.
    McPate MJ; Zhang H; Cordeiro JM; Dempsey CE; Witchel HJ; Hancox JC
    Biochem Biophys Res Commun; 2009 Aug; 386(1):111-7. PubMed ID: 19501051
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A stable cell line inducibly expressing hERG1a/1b heteromeric channels.
    Ríos-Pérez EB; Liu F; Stevens-Sostre WA; Eichel CA; Silignavong J; Robertson GA
    J Pharmacol Toxicol Methods; 2021; 110():107081. PubMed ID: 34058320
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gating and assembly of heteromeric hERG1a/1b channels underlying I(Kr) in the heart.
    Robertson GA; Jones EM; Wang J
    Novartis Found Symp; 2005; 266():4-15; discussion 15-8, 44-5. PubMed ID: 16050259
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation.
    Chen J; Zou A; Splawski I; Keating MT; Sanguinetti MC
    J Biol Chem; 1999 Apr; 274(15):10113-8. PubMed ID: 10187793
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The eag domain regulates hERG channel inactivation gating via a direct interaction.
    Gustina AS; Trudeau MC
    J Gen Physiol; 2013 Feb; 141(2):229-41. PubMed ID: 23319729
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deciphering hERG channels: molecular basis of the rapid component of the delayed rectifier potassium current.
    Jonsson MK; van der Heyden MA; van Veen TA
    J Mol Cell Cardiol; 2012 Sep; 53(3):369-74. PubMed ID: 22742967
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alternative splicing and polyadenylation contribute to the generation of hERG1 C-terminal isoforms.
    Gong Q; Stump MR; Dunn AR; Deng V; Zhou Z
    J Biol Chem; 2010 Oct; 285(42):32233-41. PubMed ID: 20693282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism.
    Malak OA; Gluhov GS; Grizel AV; Kudryashova KS; Sokolova OS; Loussouarn G
    J Biol Chem; 2019 Apr; 294(16):6506-6521. PubMed ID: 30808709
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.