191 related articles for article (PubMed ID: 22124116)
1. hERG1a N-terminal eag domain-containing polypeptides regulate homomeric hERG1b and heteromeric hERG1a/hERG1b channels: a possible mechanism for long QT syndrome.
Trudeau MC; Leung LM; Roti ER; Robertson GA
J Gen Physiol; 2011 Dec; 138(6):581-92. PubMed ID: 22124116
[TBL] [Abstract][Full Text] [Related]
2. hERG1a and hERG1b potassium channel subunits directly interact and preferentially form heteromeric channels.
McNally BA; Pendon ZD; Trudeau MC
J Biol Chem; 2017 Dec; 292(52):21548-21557. PubMed ID: 29089383
[TBL] [Abstract][Full Text] [Related]
3. Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-รก-go-go-related gene potassium channels.
Gianulis EC; Trudeau MC
J Biol Chem; 2011 Jun; 286(25):22160-9. PubMed ID: 21536673
[TBL] [Abstract][Full Text] [Related]
4. A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels.
Gustina AS; Trudeau MC
Proc Natl Acad Sci U S A; 2009 Aug; 106(31):13082-7. PubMed ID: 19651618
[TBL] [Abstract][Full Text] [Related]
5. Isoform-specific dominant-negative effects associated with hERG1 G628S mutation in long QT syndrome.
Stump MR; Gong Q; Zhou Z
PLoS One; 2012; 7(8):e42552. PubMed ID: 22876326
[TBL] [Abstract][Full Text] [Related]
6. Determinants of Isoform-Specific Gating Kinetics of hERG1 Channel: Combined Experimental and Simulation Study.
Perissinotti LL; De Biase PM; Guo J; Yang PC; Lee MC; Clancy CE; Duff HJ; Noskov SY
Front Physiol; 2018; 9():207. PubMed ID: 29706893
[TBL] [Abstract][Full Text] [Related]
7. hERG potassium channel gating is mediated by N- and C-terminal region interactions.
Gustina AS; Trudeau MC
J Gen Physiol; 2011 Mar; 137(3):315-25. PubMed ID: 21357734
[TBL] [Abstract][Full Text] [Related]
8. Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Liu QN; Trudeau MC
PLoS One; 2015; 10(4):e0123951. PubMed ID: 25923442
[TBL] [Abstract][Full Text] [Related]
9. Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.
Gianulis EC; Liu Q; Trudeau MC
J Gen Physiol; 2013 Oct; 142(4):351-66. PubMed ID: 24043860
[TBL] [Abstract][Full Text] [Related]
10. Enhanced inhibitory effect of acidosis on hERG potassium channels that incorporate the hERG1b isoform.
Du CY; El Harchi A; McPate MJ; Orchard CH; Hancox JC
Biochem Biophys Res Commun; 2011 Feb; 405(2):222-7. PubMed ID: 21219869
[TBL] [Abstract][Full Text] [Related]
11. Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.
Larsen AP; Olesen SP; Grunnet M; Jespersen T
Pflugers Arch; 2008 Sep; 456(6):1137-48. PubMed ID: 18504605
[TBL] [Abstract][Full Text] [Related]
12. hERG1a/1b heteromeric currents exhibit amplified attenuation of inactivation in variant 1 short QT syndrome.
McPate MJ; Zhang H; Cordeiro JM; Dempsey CE; Witchel HJ; Hancox JC
Biochem Biophys Res Commun; 2009 Aug; 386(1):111-7. PubMed ID: 19501051
[TBL] [Abstract][Full Text] [Related]
13. Gating and assembly of heteromeric hERG1a/1b channels underlying I(Kr) in the heart.
Robertson GA; Jones EM; Wang J
Novartis Found Symp; 2005; 266():4-15; discussion 15-8, 44-5. PubMed ID: 16050259
[TBL] [Abstract][Full Text] [Related]
14. Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation.
Chen J; Zou A; Splawski I; Keating MT; Sanguinetti MC
J Biol Chem; 1999 Apr; 274(15):10113-8. PubMed ID: 10187793
[TBL] [Abstract][Full Text] [Related]
15. The eag domain regulates hERG channel inactivation gating via a direct interaction.
Gustina AS; Trudeau MC
J Gen Physiol; 2013 Feb; 141(2):229-41. PubMed ID: 23319729
[TBL] [Abstract][Full Text] [Related]
16. Deciphering hERG channels: molecular basis of the rapid component of the delayed rectifier potassium current.
Jonsson MK; van der Heyden MA; van Veen TA
J Mol Cell Cardiol; 2012 Sep; 53(3):369-74. PubMed ID: 22742967
[TBL] [Abstract][Full Text] [Related]
17. Alternative splicing and polyadenylation contribute to the generation of hERG1 C-terminal isoforms.
Gong Q; Stump MR; Dunn AR; Deng V; Zhou Z
J Biol Chem; 2010 Oct; 285(42):32233-41. PubMed ID: 20693282
[TBL] [Abstract][Full Text] [Related]
18. Voltage-dependent activation in EAG channels follows a ligand-receptor rather than a mechanical-lever mechanism.
Malak OA; Gluhov GS; Grizel AV; Kudryashova KS; Sokolova OS; Loussouarn G
J Biol Chem; 2019 Apr; 294(16):6506-6521. PubMed ID: 30808709
[TBL] [Abstract][Full Text] [Related]
19. Physiological properties of hERG 1a/1b heteromeric currents and a hERG 1b-specific mutation associated with Long-QT syndrome.
Sale H; Wang J; O'Hara TJ; Tester DJ; Phartiyal P; He JQ; Rudy Y; Ackerman MJ; Robertson GA
Circ Res; 2008 Sep; 103(7):e81-95. PubMed ID: 18776039
[TBL] [Abstract][Full Text] [Related]
20. Fluid flow modulates electrical activity in cardiac hERG potassium channels.
Roy S; Mathew MK
J Biol Chem; 2018 Mar; 293(12):4289-4303. PubMed ID: 29305421
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
