BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

212 related articles for article (PubMed ID: 22124880)

  • 1. Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects.
    Rebello S; Zhao S; Hariry S; Dahlke M; Alexander N; Vapurcuyan A; Hanna I; Jarugula V
    Eur J Clin Pharmacol; 2012 May; 68(5):697-708. PubMed ID: 22124880
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Grapefruit juice greatly reduces the plasma concentrations of the OATP2B1 and CYP3A4 substrate aliskiren.
    Tapaninen T; Neuvonen PJ; Niemi M
    Clin Pharmacol Ther; 2010 Sep; 88(3):339-42. PubMed ID: 20664534
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.
    Bailey DG; Dresser GK; Leake BF; Kim RB
    Clin Pharmacol Ther; 2007 Apr; 81(4):495-502. PubMed ID: 17301733
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
    Dresser GK; Bailey DG; Leake BF; Schwarz UI; Dawson PA; Freeman DJ; Kim RB
    Clin Pharmacol Ther; 2002 Jan; 71(1):11-20. PubMed ID: 11823753
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Intestinal drug transporter expression and the impact of grapefruit juice in humans.
    Glaeser H; Bailey DG; Dresser GK; Gregor JC; Schwarz UI; McGrath JS; Jolicoeur E; Lee W; Leake BF; Tirona RG; Kim RB
    Clin Pharmacol Ther; 2007 Mar; 81(3):362-70. PubMed ID: 17215845
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of grapefruit juice volume on the reduction of fexofenadine bioavailability: possible role of organic anion transporting polypeptides.
    Dresser GK; Kim RB; Bailey DG
    Clin Pharmacol Ther; 2005 Mar; 77(3):170-7. PubMed ID: 15735611
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A modified grapefruit juice eliminates two compound classes as major mediators of the grapefruit juice-fexofenadine interaction: an in vitro-in vivo "connect".
    Won CS; Lan T; Vandermolen KM; Dawson PA; Oberlies NH; Widmer WW; Scarlett YV; Paine MF
    J Clin Pharmacol; 2013 Sep; 53(9):982-90. PubMed ID: 23878024
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aliskiren toxicity in juvenile rats is determined by ontogenic regulation of intestinal P-glycoprotein expression.
    Hoffmann P; Beckman D; McLean LA; Yan JH
    Toxicol Appl Pharmacol; 2014 Feb; 275(1):36-43. PubMed ID: 24388840
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Orange and apple juice greatly reduce the plasma concentrations of the OATP2B1 substrate aliskiren.
    Tapaninen T; Neuvonen PJ; Niemi M
    Br J Clin Pharmacol; 2011 May; 71(5):718-26. PubMed ID: 21204914
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fruit juice inhibition of uptake transport: a new type of food-drug interaction.
    Bailey DG
    Br J Clin Pharmacol; 2010 Nov; 70(5):645-55. PubMed ID: 21039758
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren.
    Vaidyanathan S; Camenisch G; Schuetz H; Reynolds C; Yeh CM; Bizot MN; Dieterich HA; Howard D; Dole WP
    J Clin Pharmacol; 2008 Nov; 48(11):1323-38. PubMed ID: 18784280
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Long-lasting inhibitory effect of apple and orange juices, but not grapefruit juice, on OATP2B1-mediated drug absorption.
    Shirasaka Y; Shichiri M; Murata Y; Mori T; Nakanishi T; Tamai I
    Drug Metab Dispos; 2013 Mar; 41(3):615-21. PubMed ID: 23264447
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The change of pharmacokinetics of fexofenadine enantiomers through the single and simultaneous grapefruit juice ingestion.
    Akamine Y; Miura M; Komori H; Tamai I; Ieiri I; Yasui-Furukori N; Uno T
    Drug Metab Pharmacokinet; 2015 Oct; 30(5):352-7. PubMed ID: 26213156
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.
    Shirasaka Y; Shichiri M; Mori T; Nakanishi T; Tamai I
    J Pharm Sci; 2013 Sep; 102(9):3418-26. PubMed ID: 23794501
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacokinetics, safety, and tolerability of the oral Renin inhibitor aliskiren in patients with hepatic impairment.
    Vaidyanathan S; Warren V; Yeh C; Bizot MN; Dieterich HA; Dole WP
    J Clin Pharmacol; 2007 Feb; 47(2):192-200. PubMed ID: 17244770
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacokinetics, safety and tolerability of single and multiple oral doses of aliskiren in healthy Chinese subjects: a randomized, single-blind, parallel-group, placebo-controlled study.
    Hu P; Bartlett M; Karan RS; Jiang J; Zhang S; Zhang J; Howard D; Yeh CM; Al-Fayoumi S; Jarugula V; Dole WP
    Clin Drug Investig; 2010; 30(4):221-8. PubMed ID: 20192280
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat.
    Shirasaka Y; Kuraoka E; Spahn-Langguth H; Nakanishi T; Langguth P; Tamai I
    J Pharmacol Exp Ther; 2010 Jan; 332(1):181-9. PubMed ID: 19779132
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A study of dose-proportionality in the pharmacokinetics of the oral direct renin inhibitor aliskiren in healthy subjects.
    Limoges D; Dieterich HA; Yeh CM; Vaidyanathan S; Howard D; Dole WP
    Int J Clin Pharmacol Ther; 2008 May; 46(5):252-8. PubMed ID: 18538111
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with metformin, pioglitazone and fenofibrate in healthy subjects.
    Vaidyanathan S; Maboudian M; Warren V; Yeh CM; Dieterich HA; Howard D; Dole WP
    Curr Med Res Opin; 2008 Aug; 24(8):2313-26. PubMed ID: 18786303
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prioritizing pharmacokinetic drug interaction precipitants in natural products: application to OATP inhibitors in grapefruit juice.
    Johnson EJ; Won CS; Köck K; Paine MF
    Biopharm Drug Dispos; 2017 Apr; 38(3):251-259. PubMed ID: 28032362
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.