BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

249 related articles for article (PubMed ID: 22125611)

  • 1. Microsecond molecular dynamics simulations of intrinsically disordered proteins involved in the oxidative stress response.
    Cino EA; Wong-ekkabut J; Karttunen M; Choy WY
    PLoS One; 2011; 6(11):e27371. PubMed ID: 22125611
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fuzzy complex formation between the intrinsically disordered prothymosin α and the Kelch domain of Keap1 involved in the oxidative stress response.
    Khan H; Cino EA; Brickenden A; Fan J; Yang D; Choy WY
    J Mol Biol; 2013 Mar; 425(6):1011-27. PubMed ID: 23318954
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model.
    Tong KI; Katoh Y; Kusunoki H; Itoh K; Tanaka T; Yamamoto M
    Mol Cell Biol; 2006 Apr; 26(8):2887-900. PubMed ID: 16581765
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural analysis of the complex of Keap1 with a prothymosin alpha peptide.
    Padmanabhan B; Nakamura Y; Yokoyama S
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Apr; 64(Pt 4):233-8. PubMed ID: 18391415
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Binding of Disordered Peptides to Kelch: Insights from Enhanced Sampling Simulations.
    Do TN; Choy WY; Karttunen M
    J Chem Theory Comput; 2016 Jan; 12(1):395-404. PubMed ID: 26636721
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular effects of cancer-associated somatic mutations on the structural and target recognition properties of Keap1.
    Khan H; Killoran RC; Brickenden A; Fan J; Yang D; Choy WY
    Biochem J; 2015 Apr; 467(1):141-51. PubMed ID: 25582950
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction.
    Hancock R; Bertrand HC; Tsujita T; Naz S; El-Bakry A; Laoruchupong J; Hayes JD; Wells G
    Free Radic Biol Med; 2012 Jan; 52(2):444-51. PubMed ID: 22107959
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Prothyomosin alpha interaction with KEAP1 doesn't lead to prothymosin alpha ubiquination and degradation].
    Mel'nikov SV; Evstaf'eva AG; Vartapetian AB
    Mol Biol (Mosk); 2007; 41(5):868-75. PubMed ID: 18240569
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered.
    Karunatilleke NC; Fast CS; Ngo V; Brickenden A; Duennwald ML; Konermann L; Choy WY
    Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34299054
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural insights into the multiple binding modes of Dimethyl Fumarate (DMF) and its analogs to the Kelch domain of Keap1.
    Unni S; Deshmukh P; Krishnappa G; Kommu P; Padmanabhan B
    FEBS J; 2021 Mar; 288(5):1599-1613. PubMed ID: 32672401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis.
    Stępkowski TM; Kruszewski MK
    Free Radic Biol Med; 2011 May; 50(9):1186-95. PubMed ID: 21295136
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2).
    Tian W; Rojo de la Vega M; Schmidlin CJ; Ooi A; Zhang DD
    J Biol Chem; 2018 Feb; 293(6):2029-2040. PubMed ID: 29255090
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nuclear oncoprotein prothymosin alpha is a partner of Keap1: implications for expression of oxidative stress-protecting genes.
    Karapetian RN; Evstafieva AG; Abaeva IS; Chichkova NV; Filonov GS; Rubtsov YP; Sukhacheva EA; Melnikov SV; Schneider U; Wanker EE; Vartapetian AB
    Mol Cell Biol; 2005 Feb; 25(3):1089-99. PubMed ID: 15657435
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.
    Lo SC; Li X; Henzl MT; Beamer LJ; Hannink M
    EMBO J; 2006 Aug; 25(15):3605-17. PubMed ID: 16888629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.
    Tong KI; Padmanabhan B; Kobayashi A; Shang C; Hirotsu Y; Yokoyama S; Yamamoto M
    Mol Cell Biol; 2007 Nov; 27(21):7511-21. PubMed ID: 17785452
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence for ProTα-TLR4/MD-2 binding: molecular dynamics and gravimetric assay studies.
    Omotuyi O; Matsunaga H; Ueda H
    Expert Opin Biol Ther; 2015; 15 Suppl 1():S223-9. PubMed ID: 25604147
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prothymosin α plays multifunctional cell robustness roles in genomic, epigenetic, and nongenomic mechanisms.
    Ueda H; Matsunaga H; Halder SK
    Ann N Y Acad Sci; 2012 Oct; 1269():34-43. PubMed ID: 23045968
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.
    Katoh Y; Iida K; Kang MI; Kobayashi A; Mizukami M; Tong KI; McMahon M; Hayes JD; Itoh K; Yamamoto M
    Arch Biochem Biophys; 2005 Jan; 433(2):342-50. PubMed ID: 15581590
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Binding of disordered proteins to a protein hub.
    Cino EA; Killoran RC; Karttunen M; Choy WY
    Sci Rep; 2013; 3():2305. PubMed ID: 23892546
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2.
    Eggler AL; Liu G; Pezzuto JM; van Breemen RB; Mesecar AD
    Proc Natl Acad Sci U S A; 2005 Jul; 102(29):10070-5. PubMed ID: 16006525
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.