BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 22127613)

  • 1. Global and local molecular dynamics of a bacterial carboxylesterase provide insight into its catalytic mechanism.
    Yu X; Sigler SC; Hossain D; Wierdl M; Gwaltney SR; Potter PM; Wadkins RM
    J Mol Model; 2012 Jun; 18(6):2869-83. PubMed ID: 22127613
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rational design of a carboxylic esterase RhEst1 based on computational analysis of substrate binding.
    Chen Q; Luan ZJ; Yu HL; Cheng X; Xu JH
    J Mol Graph Model; 2015 Nov; 62():319-324. PubMed ID: 26556053
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin.
    Hatfield MJ; Tsurkan L; Hyatt JL; Yu X; Edwards CC; Hicks LD; Wadkins RM; Potter PM
    Br J Pharmacol; 2010 Aug; 160(8):1916-28. PubMed ID: 20649590
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Probing the importance of hydrogen bonds in the active site of the subtilisin nattokinase by site-directed mutagenesis and molecular dynamics simulation.
    Zheng ZL; Ye MQ; Zuo ZY; Liu ZG; Tai KC; Zou GL
    Biochem J; 2006 May; 395(3):509-15. PubMed ID: 16411898
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Just an additional hydrogen bond can dramatically reduce the catalytic activity of Bacillus subtilis lipase A I12T mutant: an integration of computational modeling and experimental analysis.
    Ni Z; Jin R; Chen H; Lin X
    Comput Biol Med; 2013 Nov; 43(11):1882-8. PubMed ID: 24209933
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhancing the catalytic activity of a GH5 processive endoglucanase from Bacillus subtilis BS-5 by site-directed mutagenesis.
    Lv K; Shao W; Pedroso MM; Peng J; Wu B; Li J; He B; Schenk G
    Int J Biol Macromol; 2021 Jan; 168():442-452. PubMed ID: 33310097
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular dynamics investigation of the substrate binding mechanism in carboxylesterase.
    Chen Q; Luan ZJ; Cheng X; Xu JH
    Biochemistry; 2015 Mar; 54(9):1841-8. PubMed ID: 25711934
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Development of Bacterial Carboxylesterase Biological Recognition Elements for Cocaine Detection.
    Mustafa SA
    Mol Biotechnol; 2018 Aug; 60(8):601-607. PubMed ID: 29951737
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effect of a unique halide-stabilizing residue on the catalytic properties of haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58.
    Hasan K; Gora A; Brezovsky J; Chaloupkova R; Moskalikova H; Fortova A; Nagata Y; Damborsky J; Prokop Z
    FEBS J; 2013 Jul; 280(13):3149-59. PubMed ID: 23490078
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of the thioesterification conformation of
    Chen Y; Li TL; Lin X; Li X; Li XD; Guo Z
    J Biol Chem; 2017 Jul; 292(29):12296-12310. PubMed ID: 28559280
    [No Abstract]   [Full Text] [Related]  

  • 11. Key amino acid associated with acephate detoxification by Cydia pomonella carboxylesterase based on molecular dynamics with alanine scanning and site-directed mutagenesis.
    Yang XQ; Liu JY; Li XC; Chen MH; Zhang YL
    J Chem Inf Model; 2014 May; 54(5):1356-70. PubMed ID: 24749772
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into the mode of flavin mononucleotide binding and catalytic mechanism of bacterial chromate reductases: A molecular dynamics simulation study.
    Pradhan SK; Singh NR; Dehury B; Panda D; Modi MK; Thatoi H
    J Cell Biochem; 2019 Oct; 120(10):16990-17005. PubMed ID: 31131470
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dynamical origins of heat capacity changes in enzyme-catalysed reactions.
    van der Kamp MW; Prentice EJ; Kraakman KL; Connolly M; Mulholland AJ; Arcus VL
    Nat Commun; 2018 Mar; 9(1):1177. PubMed ID: 29563521
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular cloning of carboxylesterase gene and biochemical characterization of encoded protein from Bacillus subtilis (RRL BB1).
    Maqbool QU; Johri S; Rasool S; Riyaz-ul-Hassan S; Verma V; Nargotra A; Koul S; Qazi GN
    J Biotechnol; 2006 Aug; 125(1):1-10. PubMed ID: 16621096
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Insights into specificity and catalytic mechanism of amphotericin B/nystatin thioesterase.
    Wang R; Tao W; Liu L; Li C; Bai L; Zhao YL; Shi T
    Proteins; 2021 May; 89(5):558-568. PubMed ID: 33389775
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amino acid residues adjacent to the catalytic cavity of tetramer L-asparaginase II contribute significantly to its catalytic efficiency and thermostability.
    Long S; Zhang X; Rao Z; Chen K; Xu M; Yang T; Yang S
    Enzyme Microb Technol; 2016 Jan; 82():15-22. PubMed ID: 26672444
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insights into the fatty acid chain length specificity of the carboxylesterase PA3859 from Pseudomonas aeruginosa: A combined structural, biochemical and computational study.
    Pesaresi A; Lamba D
    Biochimie; 2010 Dec; 92(12):1787-92. PubMed ID: 20850500
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of a feruloyl esterase belonging to the tannase family: a disulfide bond near a catalytic triad.
    Suzuki K; Hori A; Kawamoto K; Thangudu RR; Ishida T; Igarashi K; Samejima M; Yamada C; Arakawa T; Wakagi T; Koseki T; Fushinobu S
    Proteins; 2014 Oct; 82(10):2857-67. PubMed ID: 25066066
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Importance of Loop L1 Dynamics for Substrate Capture and Catalysis in Pseudomonas aeruginosa d-Arginine Dehydrogenase.
    Ouedraogo D; Souffrant M; Vasquez S; Hamelberg D; Gadda G
    Biochemistry; 2017 May; 56(19):2477-2487. PubMed ID: 28445031
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural insights into the catalytic active site and activity of human Nit2/ω-amidase: kinetic assay and molecular dynamics simulation.
    Chien CH; Gao QZ; Cooper AJ; Lyu JH; Sheu SY
    J Biol Chem; 2012 Jul; 287(31):25715-26. PubMed ID: 22674578
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.