262 related articles for article (PubMed ID: 22128174)
1. Modulation of heme/substrate binding cleft of neuronal nitric-oxide synthase (nNOS) regulates binding of Hsp90 and Hsp70 proteins and nNOS ubiquitination.
Peng HM; Morishima Y; Pratt WB; Osawa Y
J Biol Chem; 2012 Jan; 287(2):1556-65. PubMed ID: 22128174
[TBL] [Abstract][Full Text] [Related]
2. Dynamic cycling with Hsp90 stabilizes neuronal nitric oxide synthase through calmodulin-dependent inhibition of ubiquitination.
Peng HM; Morishima Y; Clapp KM; Lau M; Pratt WB; Osawa Y
Biochemistry; 2009 Sep; 48(35):8483-90. PubMed ID: 19642705
[TBL] [Abstract][Full Text] [Related]
3. C331A mutant of neuronal nitric-oxide synthase is labilized for Hsp70/CHIP (C terminus of HSC70-interacting protein)-dependent ubiquitination.
Clapp KM; Peng HM; Morishima Y; Lau M; Walker VJ; Pratt WB; Osawa Y
J Biol Chem; 2010 Oct; 285(44):33642-51. PubMed ID: 20729196
[TBL] [Abstract][Full Text] [Related]
4. Ubiquitination of neuronal nitric-oxide synthase in the calmodulin-binding site triggers proteasomal degradation of the protein.
Clapp KM; Peng HM; Jenkins GJ; Ford MJ; Morishima Y; Lau M; Osawa Y
J Biol Chem; 2012 Dec; 287(51):42601-10. PubMed ID: 23109339
[TBL] [Abstract][Full Text] [Related]
5. The role of hsp90 in heme-dependent activation of apo-neuronal nitric-oxide synthase.
Billecke SS; Draganov DI; Morishima Y; Murphy PJ; Dunbar AY; Pratt WB; Osawa Y
J Biol Chem; 2004 Jul; 279(29):30252-8. PubMed ID: 15155759
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of hsp70 by methylene blue affects signaling protein function and ubiquitination and modulates polyglutamine protein degradation.
Wang AM; Morishima Y; Clapp KM; Peng HM; Pratt WB; Gestwicki JE; Osawa Y; Lieberman AP
J Biol Chem; 2010 May; 285(21):15714-23. PubMed ID: 20348093
[TBL] [Abstract][Full Text] [Related]
7. Hsp70:CHIP Ubiquitinates Dysfunctional but Not Native Neuronal NO Synthase.
Davis AK; McMyn NF; Lau M; Morishima Y; Osawa Y
Mol Pharmacol; 2020 Sep; 98(3):243-249. PubMed ID: 32591478
[TBL] [Abstract][Full Text] [Related]
8. Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage.
Pratt WB; Morishima Y; Peng HM; Osawa Y
Exp Biol Med (Maywood); 2010 Mar; 235(3):278-89. PubMed ID: 20404045
[TBL] [Abstract][Full Text] [Related]
9. Neuronal nitric-oxide synthase is regulated by the Hsp90-based chaperone system in vivo.
Bender AT; Silverstein AM; Demady DR; Kanelakis KC; Noguchi S; Pratt WB; Osawa Y
J Biol Chem; 1999 Jan; 274(3):1472-8. PubMed ID: 9880522
[TBL] [Abstract][Full Text] [Related]
10. Ca2+/S100 proteins act as upstream regulators of the chaperone-associated ubiquitin ligase CHIP (C terminus of Hsc70-interacting protein).
Shimamoto S; Kubota Y; Yamaguchi F; Tokumitsu H; Kobayashi R
J Biol Chem; 2013 Mar; 288(10):7158-68. PubMed ID: 23344957
[TBL] [Abstract][Full Text] [Related]
11. Heme-dependent activation of neuronal nitric oxide synthase by cytosol is due to an Hsp70-dependent, thioredoxin-mediated thiol-disulfide interchange in the heme/substrate binding cleft.
Morishima Y; Lau M; Peng HM; Miyata Y; Gestwicki JE; Pratt WB; Osawa Y
Biochemistry; 2011 Aug; 50(33):7146-56. PubMed ID: 21755988
[TBL] [Abstract][Full Text] [Related]
12. Dynamic cycling with a unique Hsp90/Hsp70-dependent chaperone machinery and GAPDH is needed for heme insertion and activation of neuronal NO synthase.
Morishima Y; Lau M; Pratt WB; Osawa Y
J Biol Chem; 2023 Feb; 299(2):102856. PubMed ID: 36596358
[TBL] [Abstract][Full Text] [Related]
13. Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase.
Peng HM; Morishima Y; Jenkins GJ; Dunbar AY; Lau M; Patterson C; Pratt WB; Osawa Y
J Biol Chem; 2004 Dec; 279(51):52970-7. PubMed ID: 15466472
[TBL] [Abstract][Full Text] [Related]
14. The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradation.
Ahmed SF; Deb S; Paul I; Chatterjee A; Mandal T; Chatterjee U; Ghosh MK
J Biol Chem; 2012 May; 287(19):15996-6006. PubMed ID: 22427670
[TBL] [Abstract][Full Text] [Related]
15. The ubiquitin ligase CHIP regulates c-Myc stability and transcriptional activity.
Paul I; Ahmed SF; Bhowmik A; Deb S; Ghosh MK
Oncogene; 2013 Mar; 32(10):1284-95. PubMed ID: 22543587
[TBL] [Abstract][Full Text] [Related]
16. Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases.
Pratt WB; Gestwicki JE; Osawa Y; Lieberman AP
Annu Rev Pharmacol Toxicol; 2015; 55():353-71. PubMed ID: 25292434
[TBL] [Abstract][Full Text] [Related]
17. C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow.
Sun X; Fratz S; Sharma S; Hou Y; Rafikov R; Kumar S; Rehmani I; Tian J; Smith A; Schreiber C; Reiser J; Naumann S; Haag S; Hess J; Catravas JD; Patterson C; Fineman JR; Black SM
Am J Respir Cell Mol Biol; 2011 Jul; 45(1):163-71. PubMed ID: 20870896
[TBL] [Abstract][Full Text] [Related]
18. Ubiquitination and degradation of neuronal nitric-oxide synthase in vitro: dimer stabilization protects the enzyme from proteolysis.
Dunbar AY; Kamada Y; Jenkins GJ; Lowe ER; Billecke SS; Osawa Y
Mol Pharmacol; 2004 Oct; 66(4):964-9. PubMed ID: 15235101
[TBL] [Abstract][Full Text] [Related]
19. Hsp70 and Hsp90 oppositely regulate TGF-β signaling through CHIP/Stub1.
Shang Y; Xu X; Duan X; Guo J; Wang Y; Ren F; He D; Chang Z
Biochem Biophys Res Commun; 2014 Mar; 446(1):387-92. PubMed ID: 24613385
[TBL] [Abstract][Full Text] [Related]
20. Hsp70 and Hsp90 multichaperone complexes sequentially regulate thiazide-sensitive cotransporter endoplasmic reticulum-associated degradation and biogenesis.
Donnelly BF; Needham PG; Snyder AC; Roy A; Khadem S; Brodsky JL; Subramanya AR
J Biol Chem; 2013 May; 288(18):13124-35. PubMed ID: 23482560
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
