166 related articles for article (PubMed ID: 22132744)
1. Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes.
Wu Y; Steinbergs N; Murray-Stewart T; Marton LJ; Casero RA
Biochem J; 2012 Mar; 442(3):693-701. PubMed ID: 22132744
[TBL] [Abstract][Full Text] [Related]
2. Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes.
Huang Y; Stewart TM; Wu Y; Baylin SB; Marton LJ; Perkins B; Jones RJ; Woster PM; Casero RA
Clin Cancer Res; 2009 Dec; 15(23):7217-28. PubMed ID: 19934284
[TBL] [Abstract][Full Text] [Related]
3. The re-expression of the epigenetically silenced e-cadherin gene by a polyamine analogue lysine-specific demethylase-1 (LSD1) inhibitor in human acute myeloid leukemia cell lines.
Murray-Stewart T; Woster PM; Casero RA
Amino Acids; 2014 Mar; 46(3):585-94. PubMed ID: 23508577
[TBL] [Abstract][Full Text] [Related]
4. Polyamine analogues targeting epigenetic gene regulation.
Huang Y; Marton LJ; Woster PM; Casero RA
Essays Biochem; 2009 Nov; 46():95-110. PubMed ID: 20095972
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes.
Huang Y; Greene E; Murray Stewart T; Goodwin AC; Baylin SB; Woster PM; Casero RA
Proc Natl Acad Sci U S A; 2007 May; 104(19):8023-8. PubMed ID: 17463086
[TBL] [Abstract][Full Text] [Related]
6. Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner.
Jin L; Hanigan CL; Wu Y; Wang W; Park BH; Woster PM; Casero RA
Biochem J; 2013 Jan; 449(2):459-68. PubMed ID: 23072722
[TBL] [Abstract][Full Text] [Related]
7. Regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2 (LSD1 and LSD2).
Mino K; Nishimura S; Ninomiya S; Tujii H; Matsumori Y; Tsuchida M; Hosoi M; Koseki K; Wada S; Hasegawa M; Sasaki R; Murakami-Yamaguchi Y; Narita H; Suzuki T; Miyata N; Mizukami T
Biosci Biotechnol Biochem; 2014; 78(6):1010-7. PubMed ID: 25036127
[TBL] [Abstract][Full Text] [Related]
8. Polyamine analogs modulate gene expression by inhibiting lysine-specific demethylase 1 (LSD1) and altering chromatin structure in human breast cancer cells.
Zhu Q; Huang Y; Marton LJ; Woster PM; Davidson NE; Casero RA
Amino Acids; 2012 Feb; 42(2-3):887-98. PubMed ID: 21805138
[TBL] [Abstract][Full Text] [Related]
9. Silencing of LSD1 gene modulates histone methylation and acetylation and induces the apoptosis of JeKo-1 and MOLT-4 cells.
Zou ZK; Huang YQ; Zou Y; Zheng XK; Ma XD
Int J Mol Med; 2017 Aug; 40(2):319-328. PubMed ID: 28627608
[TBL] [Abstract][Full Text] [Related]
10. (Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators.
Sharma SK; Wu Y; Steinbergs N; Crowley ML; Hanson AS; Casero RA; Woster PM
J Med Chem; 2010 Jul; 53(14):5197-212. PubMed ID: 20568780
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells.
Katz TA; Vasilatos SN; Harrington E; Oesterreich S; Davidson NE; Huang Y
Breast Cancer Res Treat; 2014 Jul; 146(1):99-108. PubMed ID: 24924415
[TBL] [Abstract][Full Text] [Related]
12. AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.
Samal K; Zhao P; Kendzicky A; Yco LP; McClung H; Gerner E; Burns M; Bachmann AS; Sholler G
Int J Cancer; 2013 Sep; 133(6):1323-33. PubMed ID: 23457004
[TBL] [Abstract][Full Text] [Related]
13. Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells.
Vasilatos SN; Katz TA; Oesterreich S; Wan Y; Davidson NE; Huang Y
Carcinogenesis; 2013 Jun; 34(6):1196-207. PubMed ID: 23354309
[TBL] [Abstract][Full Text] [Related]
14. Differential effects of polyamine homologues on the prevention of DL-alpha-difluoromethylornithine-mediated inhibition of malignant cell growth and normal immune response.
Singh AB; Thomas TJ; Thomas T; Singh M; Mann RA
Cancer Res; 1992 Apr; 52(7):1840-7. PubMed ID: 1551114
[TBL] [Abstract][Full Text] [Related]
15. DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines.
Kawamoto K; Hirata H; Kikuno N; Tanaka Y; Nakagawa M; Dahiya R
Int J Cancer; 2008 Aug; 123(3):535-42. PubMed ID: 18404682
[TBL] [Abstract][Full Text] [Related]
16. Structure-activity study for (bis)ureidopropyl- and (bis)thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures.
Nowotarski SL; Pachaiyappan B; Holshouser SL; Kutz CJ; Li Y; Huang Y; Sharma SK; Casero RA; Woster PM
Bioorg Med Chem; 2015 Apr; 23(7):1601-12. PubMed ID: 25725609
[TBL] [Abstract][Full Text] [Related]
17. Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1.
Hazeldine S; Pachaiyappan B; Steinbergs N; Nowotarski S; Hanson AS; Casero RA; Woster PM
J Med Chem; 2012 Sep; 55(17):7378-91. PubMed ID: 22876979
[TBL] [Abstract][Full Text] [Related]
18. Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines.
Meng CF; Zhu XJ; Peng G; Dai DQ
World J Gastroenterol; 2007 Dec; 13(46):6166-71. PubMed ID: 18069755
[TBL] [Abstract][Full Text] [Related]
19. Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.
Metzger E; Imhof A; Patel D; Kahl P; Hoffmeyer K; Friedrichs N; Müller JM; Greschik H; Kirfel J; Ji S; Kunowska N; Beisenherz-Huss C; Günther T; Buettner R; Schüle R
Nature; 2010 Apr; 464(7289):792-6. PubMed ID: 20228790
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of polyamine synthesis induces p53 gene expression but not apoptosis.
Li L; Li J; Rao JN; Li M; Bass BL; Wang JY
Am J Physiol; 1999 Apr; 276(4):C946-54. PubMed ID: 10199827
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
