These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 22138033)

  • 1. Selective inhibitory effect of HPMA copolymer-cyclopamine conjugate on prostate cancer stem cells.
    Zhou Y; Yang J; Kopeček J
    Biomaterials; 2012 Feb; 33(6):1863-72. PubMed ID: 22138033
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HPMA copolymer-based combination therapy toxic to both prostate cancer stem/progenitor cells and differentiated cells induces durable anti-tumor effects.
    Zhou Y; Yang J; Rhim JS; Kopeček J
    J Control Release; 2013 Dec; 172(3):946-53. PubMed ID: 24041709
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective release of a cyclopamine glucuronide prodrug toward stem-like cancer cell inhibition in glioblastoma.
    Balbous A; Renoux B; Cortes U; Milin S; Guilloteau K; Legigan T; Rivet P; Boissonnade O; Martin S; Tripiana C; Wager M; Bensadoun RJ; Papot S; Karayan-Tapon L
    Mol Cancer Ther; 2014 Sep; 13(9):2159-69. PubMed ID: 25053823
    [TBL] [Abstract][Full Text] [Related]  

  • 4. One Hundred Faces of Cyclopamine.
    Iovine V; Mori M; Calcaterra A; Berardozzi S; Botta B
    Curr Pharm Des; 2016; 22(12):1658-81. PubMed ID: 26759083
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HPMA copolymer-1,5-diazaanthraquinone conjugates as novel anticancer therapeutics.
    Vicent MJ; Manzanaro S; de la Fuente JA; Duncan R
    J Drug Target; 2004; 12(8):503-15. PubMed ID: 15621676
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer.
    Steg A; Amm HM; Novak Z; Frost AR; Johnson MR
    Cancer Biol Ther; 2010 Nov; 10(9):893-902. PubMed ID: 20814245
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and bioactivity of poly(HPMA)-lysozyme conjugates: the use of novel thiazolidine-2-thione coupling chemistry.
    Tao L; Liu J; Xu J; Davis TP
    Org Biomol Chem; 2009 Sep; 7(17):3481-5. PubMed ID: 19675903
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytotoxic effects induced by a combination of cyclopamine and gefitinib, the selective hedgehog and epidermal growth factor receptor signaling inhibitors, in prostate cancer cells.
    Mimeault M; Moore E; Moniaux N; Hénichart JP; Depreux P; Lin MF; Batra SK
    Int J Cancer; 2006 Feb; 118(4):1022-31. PubMed ID: 16108016
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A prostate-specific antigen activated N-(2-hydroxypropyl) methacrylamide copolymer prodrug as dual-targeted therapy for prostate cancer.
    Chandran SS; Nan A; Rosen DM; Ghandehari H; Denmeade SR
    Mol Cancer Ther; 2007 Nov; 6(11):2928-37. PubMed ID: 18025277
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combination therapy of prostate cancer with HPMA copolymer conjugates containing PI3K/mTOR inhibitor and docetaxel.
    Zhou Y; Yang J; Zhang R; Kopeček J
    Eur J Pharm Biopharm; 2015 Jan; 89():107-15. PubMed ID: 25481033
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells.
    Chen M; Feuerstein MA; Levina E; Baghel PS; Carkner RD; Tanner MJ; Shtutman M; Vacherot F; Terry S; de la Taille A; Buttyan R
    Mol Cancer; 2010 Apr; 9():89. PubMed ID: 20420697
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the hedgehog pathway: the development of cyclopamine and the development of anti-cancer drugs targeting the hedgehog pathway.
    Gould A; Missailidis S
    Mini Rev Med Chem; 2011 Mar; 11(3):200-13. PubMed ID: 21222574
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hyaluronic acid functional amphipathic and redox-responsive polymer particles for the co-delivery of doxorubicin and cyclopamine to eradicate breast cancer cells and cancer stem cells.
    Hu K; Zhou H; Liu Y; Liu Z; Liu J; Tang J; Li J; Zhang J; Sheng W; Zhao Y; Wu Y; Chen C
    Nanoscale; 2015 May; 7(18):8607-18. PubMed ID: 25898852
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cyclopamine sensitizes glioblastoma cells to temozolomide treatment through Sonic hedgehog pathway.
    Carballo GB; Matias D; Ribeiro JH; Pessoa LS; Arrais-Neto AM; Spohr TCLSE
    Life Sci; 2020 Sep; 257():118027. PubMed ID: 32622951
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumor-derived human prostate epithelial cell lines and in prostate cancer specimens.
    Miki J; Furusato B; Li H; Gu Y; Takahashi H; Egawa S; Sesterhenn IA; McLeod DG; Srivastava S; Rhim JS
    Cancer Res; 2007 Apr; 67(7):3153-61. PubMed ID: 17409422
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Star structure of antibody-targeted HPMA copolymer-bound doxorubicin: a novel type of polymeric conjugate for targeted drug delivery with potent antitumor effect.
    Kovár M; Strohalm J; Etrych T; Ulbrich K; Ríhová B
    Bioconjug Chem; 2002; 13(2):206-15. PubMed ID: 11906257
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926).
    Tremblay MR; Lescarbeau A; Grogan MJ; Tan E; Lin G; Austad BC; Yu LC; Behnke ML; Nair SJ; Hagel M; White K; Conley J; Manna JD; Alvarez-Diez TM; Hoyt J; Woodward CN; Sydor JR; Pink M; MacDougall J; Campbell MJ; Cushing J; Ferguson J; Curtis MS; McGovern K; Read MA; Palombella VJ; Adams J; Castro AC
    J Med Chem; 2009 Jul; 52(14):4400-18. PubMed ID: 19522463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combination therapy of paclitaxel and cyclopamine polymer-drug conjugates to treat advanced prostate cancer.
    Yang R; Mondal G; Wen D; Mahato RI
    Nanomedicine; 2017 Feb; 13(2):391-401. PubMed ID: 27520724
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition.
    Miyazaki Y; Matsubara S; Ding Q; Tsukasa K; Yoshimitsu M; Kosai K; Takao S
    Mol Cancer; 2016 Jun; 15(1):49. PubMed ID: 27349387
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway.
    Singh S; Chitkara D; Mehrazin R; Behrman SW; Wake RW; Mahato RI
    PLoS One; 2012; 7(6):e40021. PubMed ID: 22768203
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.