These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 22140478)

  • 1. Raloxifene and desmethylarzoxifene block estrogen-induced malignant transformation of human breast epithelial cells.
    Kastrati I; Edirisinghe PD; Hemachandra LP; Chandrasena ER; Choi J; Wang YT; Bolton JL; Thatcher GR
    PLoS One; 2011; 6(11):e27876. PubMed ID: 22140478
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites.
    Hemachandra LP; Patel H; Chandrasena RE; Choi J; Piyankarage SC; Wang S; Wang Y; Thayer EN; Scism RA; Michalsen BT; Xiong R; Siklos MI; Bolton JL; Thatcher GR
    Cancer Prev Res (Phila); 2014 May; 7(5):505-15. PubMed ID: 24598415
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens.
    Wang Z; Chandrasena ER; Yuan Y; Peng KW; van Breemen RB; Thatcher GR; Bolton JL
    Chem Res Toxicol; 2010 Aug; 23(8):1365-73. PubMed ID: 20509668
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural modulation of reactivity/activity in design of improved benzothiophene selective estrogen receptor modulators: induction of chemopreventive mechanisms.
    Yu B; Dietz BM; Dunlap T; Kastrati I; Lantvit DD; Overk CR; Yao P; Qin Z; Bolton JL; Thatcher GR
    Mol Cancer Ther; 2007 Sep; 6(9):2418-28. PubMed ID: 17876041
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemical modification modulates estrogenic activity, oxidative reactivity, and metabolic stability in 4'F-DMA, a new benzothiophene selective estrogen receptor modulator.
    Liu H; Bolton JL; Thatcher GR
    Chem Res Toxicol; 2006 Jun; 19(6):779-87. PubMed ID: 16780356
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure-activity relationships for a family of benzothiophene selective estrogen receptor modulators including raloxifene and arzoxifene.
    Overk CR; Peng KW; Asghodom RT; Kastrati I; Lantvit DD; Qin Z; Frasor J; Bolton JL; Thatcher GR
    ChemMedChem; 2007 Oct; 2(10):1520-6. PubMed ID: 17654759
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanisms of estrogen carcinogenesis: The role of E2/E1-quinone metabolites suggests new approaches to preventive intervention--A review.
    Yager JD
    Steroids; 2015 Jul; 99(Pt A):56-60. PubMed ID: 25159108
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Potential mechanisms of estrogen quinone carcinogenesis.
    Bolton JL; Thatcher GR
    Chem Res Toxicol; 2008 Jan; 21(1):93-101. PubMed ID: 18052105
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reactive oxygen species via redox signaling to PI3K/AKT pathway contribute to the malignant growth of 4-hydroxy estradiol-transformed mammary epithelial cells.
    Okoh VO; Felty Q; Parkash J; Poppiti R; Roy D
    PLoS One; 2013; 8(2):e54206. PubMed ID: 23437041
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hops (Humulus lupulus) inhibits oxidative estrogen metabolism and estrogen-induced malignant transformation in human mammary epithelial cells (MCF-10A).
    Hemachandra LP; Madhubhani P; Chandrasena R; Esala P; Chen SN; Main M; Lankin DC; Scism RA; Dietz BM; Pauli GF; Thatcher GR; Bolton JL
    Cancer Prev Res (Phila); 2012 Jan; 5(1):73-81. PubMed ID: 21997247
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective estrogen receptor modulator delivery of quinone warheads to DNA triggering apoptosis in breast cancer cells.
    Peng KW; Wang H; Qin Z; Wijewickrama GT; Lu M; Wang Z; Bolton JL; Thatcher GR
    ACS Chem Biol; 2009 Dec; 4(12):1039-49. PubMed ID: 19839584
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Uterine peroxidase-catalyzed formation of diquinone methides from the selective estrogen receptor modulators raloxifene and desmethylated arzoxifene.
    Liu H; Qin Z; Thatcher GR; Bolton JL
    Chem Res Toxicol; 2007 Nov; 20(11):1676-84. PubMed ID: 17630709
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention.
    Cavalieri E; Chakravarti D; Guttenplan J; Hart E; Ingle J; Jankowiak R; Muti P; Rogan E; Russo J; Santen R; Sutter T
    Biochim Biophys Acta; 2006 Aug; 1766(1):63-78. PubMed ID: 16675129
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The effects of catechol-O-methyltransferase inhibition on estrogen metabolite and oxidative DNA damage levels in estradiol-treated MCF-7 cells.
    Lavigne JA; Goodman JE; Fonong T; Odwin S; He P; Roberts DW; Yager JD
    Cancer Res; 2001 Oct; 61(20):7488-94. PubMed ID: 11606384
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The molecular etiology and prevention of estrogen-initiated cancers: Ockham's Razor: Pluralitas non est ponenda sine necessitate. Plurality should not be posited without necessity.
    Cavalieri E; Rogan E
    Mol Aspects Med; 2014 Apr; 36():1-55. PubMed ID: 23994691
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Water extract of Er-xian decoction selectively exerts estrogenic activities and interacts with SERMs in estrogen-sensitive tissues.
    Wong KY; Zhou L; Yu W; Poon CC; Xiao H; Chan CO; Mok DK; Wong MS
    J Ethnopharmacol; 2021 Jul; 275():114096. PubMed ID: 33823166
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of oral estrogen, raloxifene and arzoxifene on gene expression in serotonin neurons of macaques.
    Bethea CL; Mirkes SJ; Su A; Michelson D
    Psychoneuroendocrinology; 2002 May; 27(4):431-45. PubMed ID: 11911997
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reduction of estrogen-induced transformation of mouse mammary epithelial cells by N-acetylcysteine.
    Venugopal D; Zahid M; Mailander PC; Meza JL; Rogan EG; Cavalieri EL; Chakravarti D
    J Steroid Biochem Mol Biol; 2008 Mar; 109(1-2):22-30. PubMed ID: 18226522
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Resveratrol prevents estrogen-DNA adduct formation and neoplastic transformation in MCF-10F cells.
    Lu F; Zahid M; Wang C; Saeed M; Cavalieri EL; Rogan EG
    Cancer Prev Res (Phila); 2008 Jul; 1(2):135-45. PubMed ID: 19138946
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The effect of tamoxifen and raloxifene on estrogen metabolism and endometrial cancer risk.
    Williams-Brown MY; Salih SM; Xu X; Veenstra TD; Saeed M; Theiler SK; Diaz-Arrastia CR; Salama SA
    J Steroid Biochem Mol Biol; 2011 Sep; 126(3-5):78-86. PubMed ID: 21600284
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.