These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

291 related articles for article (PubMed ID: 22140559)

  • 1. MUC1-C oncoprotein regulates glycolysis and pyruvate kinase M2 activity in cancer cells.
    Kosugi M; Ahmad R; Alam M; Uchida Y; Kufe D
    PLoS One; 2011; 6(11):e28234. PubMed ID: 22140559
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Beta-elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation.
    Pan Y; Wang W; Huang S; Ni W; Wei Z; Cao Y; Yu S; Jia Q; Wu Y; Chai C; Zheng Q; Zhang L; Wang A; Sun Z; Huang S; Wang S; Chen W; Lu Y
    J Cell Mol Med; 2019 Oct; 23(10):6846-6858. PubMed ID: 31343107
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
    Sun Q; Chen X; Ma J; Peng H; Wang F; Zha X; Wang Y; Jing Y; Yang H; Chen R; Chang L; Zhang Y; Goto J; Onda H; Chen T; Wang MR; Lu Y; You H; Kwiatkowski D; Zhang H
    Proc Natl Acad Sci U S A; 2011 Mar; 108(10):4129-34. PubMed ID: 21325052
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NEK2 Promotes Aerobic Glycolysis in Multiple Myeloma Through Regulating Splicing of Pyruvate Kinase.
    Gu Z; Xia J; Xu H; Frech I; Tricot G; Zhan F
    J Hematol Oncol; 2017 Jan; 10(1):17. PubMed ID: 28086949
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p,p'-Dichlorodiphenyltrichloroethane promotes aerobic glycolysis via reactive oxygen species-mediated extracellular signal-regulated kinase/M2 isoform of pyruvate kinase (PKM2) signaling in colorectal cancer cells.
    Song L; Dong N; Li Z
    Environ Toxicol; 2020 Mar; 35(3):333-345. PubMed ID: 31724279
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation.
    Yang W; Xia Y; Ji H; Zheng Y; Liang J; Huang W; Gao X; Aldape K; Lu Z
    Nature; 2011 Dec; 480(7375):118-22. PubMed ID: 22056988
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of the MUC1-C Cytoplasmic Domain as a Cancer Target.
    Raina D; Agarwal P; Lee J; Bharti A; McKnight CJ; Sharma P; Kharbanda S; Kufe D
    PLoS One; 2015; 10(8):e0135156. PubMed ID: 26267657
    [TBL] [Abstract][Full Text] [Related]  

  • 8. EGF promotes PKM2 O-GlcNAcylation by stimulating O-GlcNAc transferase phosphorylation at Y976 and their subsequent association.
    Wang Y; Shu H; Liu J; Jin X; Wang L; Qu Y; Xia M; Peng P; Feng Y; Wei M
    J Biol Chem; 2022 Sep; 298(9):102340. PubMed ID: 35931120
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The MUC1 and galectin-3 oncoproteins function in a microRNA-dependent regulatory loop.
    Ramasamy S; Duraisamy S; Barbashov S; Kawano T; Kharbanda S; Kufe D
    Mol Cell; 2007 Sep; 27(6):992-1004. PubMed ID: 17889671
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia.
    Li M; Lu H; Wang X; Duan C; Zhu X; Zhang Y; Ge X; Ji F; Wang X; Su J; Zhang D
    Mol Immunol; 2021 Dec; 140():250-266. PubMed ID: 34798593
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting the eIF4A RNA helicase blocks translation of the MUC1-C oncoprotein.
    Jin C; Rajabi H; Rodrigo CM; Porco JA; Kufe D
    Oncogene; 2013 Apr; 32(17):2179-88. PubMed ID: 22689062
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Resveratrol inhibits cancer cell metabolism by down regulating pyruvate kinase M2 via inhibition of mammalian target of rapamycin.
    Iqbal MA; Bamezai RN
    PLoS One; 2012; 7(5):e36764. PubMed ID: 22574221
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nonmetabolic functions of pyruvate kinase isoform M2 in controlling cell cycle progression and tumorigenesis.
    Lu Z
    Chin J Cancer; 2012 Jan; 31(1):5-7. PubMed ID: 22200182
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of pyruvate kinase M2-regulating aerobic glycolysis on chemotherapy resistance of estrogen receptor-positive breast cancer.
    Qian Y; Bi L; Yang Y; Wang D
    Anticancer Drugs; 2018 Aug; 29(7):616-627. PubMed ID: 29782350
    [TBL] [Abstract][Full Text] [Related]  

  • 15. HSP40 interacts with pyruvate kinase M2 and regulates glycolysis and cell proliferation in tumor cells.
    Huang L; Yu Z; Zhang T; Zhao X; Huang G
    PLoS One; 2014; 9(3):e92949. PubMed ID: 24658033
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting cysteine-mediated dimerization of the MUC1-C oncoprotein in human cancer cells.
    Raina D; Ahmad R; Rajabi H; Panchamoorthy G; Kharbanda S; Kufe D
    Int J Oncol; 2012 May; 40(5):1643-9. PubMed ID: 22200620
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth.
    Hitosugi T; Kang S; Vander Heiden MG; Chung TW; Elf S; Lythgoe K; Dong S; Lonial S; Wang X; Chen GZ; Xie J; Gu TL; Polakiewicz RD; Roesel JL; Boggon TJ; Khuri FR; Gilliland DG; Cantley LC; Kaufman J; Chen J
    Sci Signal; 2009 Nov; 2(97):ra73. PubMed ID: 19920251
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pyruvate kinase M2 affects liver cancer cell behavior through up-regulation of HIF-1α and Bcl-xL in culture.
    Dong T; Yan Y; Chai H; Chen S; Xiong X; Sun D; Yu Y; Deng L; Cheng F
    Biomed Pharmacother; 2015 Feb; 69():277-84. PubMed ID: 25661370
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin enhances metabolic capacities of cancer cells by dual regulation of glycolytic enzyme pyruvate kinase M2.
    Iqbal MA; Siddiqui FA; Gupta V; Chattopadhyay S; Gopinath P; Kumar B; Manvati S; Chaman N; Bamezai RN
    Mol Cancer; 2013 Jul; 12():72. PubMed ID: 23837608
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Death-associated protein kinase increases glycolytic rate through binding and activation of pyruvate kinase.
    Mor I; Carlessi R; Ast T; Feinstein E; Kimchi A
    Oncogene; 2012 Feb; 31(6):683-93. PubMed ID: 21725354
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.