BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 22144113)

  • 21. Prediction of HIV-1 integrase/viral DNA interactions in the catalytic domain by fast molecular docking.
    Adesokan AA; Roberts VA; Lee KW; Lins RD; Briggs JM
    J Med Chem; 2004 Feb; 47(4):821-8. PubMed ID: 14761184
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Modeling, analysis, and validation of a novel HIV integrase structure provide insights into the binding modes of potent integrase inhibitors.
    Chen X; Tsiang M; Yu F; Hung M; Jones GS; Zeynalzadegan A; Qi X; Jin H; Kim CU; Swaminathan S; Chen JM
    J Mol Biol; 2008 Jul; 380(3):504-19. PubMed ID: 18565342
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Molecular mechanisms of HIV integration and therapeutic intervention.
    Vandegraaff N; Engelman A
    Expert Rev Mol Med; 2007 Feb; 9(6):1-19. PubMed ID: 17320002
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Resistance to HIV-1 integrase inhibitors: A structural perspective.
    Mouscadet JF; Delelis O; Marcelin AG; Tchertanov L
    Drug Resist Updat; 2010; 13(4-5):139-50. PubMed ID: 20570551
    [TBL] [Abstract][Full Text] [Related]  

  • 25. X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
    Chen Z; Yan Y; Munshi S; Li Y; Zugay-Murphy J; Xu B; Witmer M; Felock P; Wolfe A; Sardana V; Emini EA; Hazuda D; Kuo LC
    J Mol Biol; 2000 Feb; 296(2):521-33. PubMed ID: 10669606
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Antiretroviral agents as inhibitors of both human immunodeficiency virus type 1 integrase and protease.
    Mazumder A; Wang S; Neamati N; Nicklaus M; Sunder S; Chen J; Milne GW; Rice WG; Burke TR; Pommier Y
    J Med Chem; 1996 Jun; 39(13):2472-81. PubMed ID: 8691444
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Molecular dynamics of HIV1-integrase in complex with 93del - a structural perspective on the mechanism of inhibition.
    Sgobba M; Olubiyi O; Ke S; Haider S
    J Biomol Struct Dyn; 2012; 29(5):863-77. PubMed ID: 22292948
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A novel short peptide is a specific inhibitor of the human immunodeficiency virus type 1 integrase.
    de Soultrait VR; Caumont A; Parissi V; Morellet N; Ventura M; Lenoir C; Litvak S; Fournier M; Roques B
    J Mol Biol; 2002 Apr; 318(1):45-58. PubMed ID: 12054767
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Unprocessed viral DNA could be the primary target of the HIV-1 integrase inhibitor raltegravir.
    Ammar FF; Abdel-Azeim S; Zargarian L; Hobaika Z; Maroun RG; Fermandjian S
    PLoS One; 2012; 7(7):e40223. PubMed ID: 22768342
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Molecular dynamics simulations of the HIV-1 integrase dimerization interface: guidelines for the design of a novel class of integrase inhibitors.
    Sippel M; Sotriffer CA
    J Chem Inf Model; 2010 Apr; 50(4):604-14. PubMed ID: 20230013
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex.
    Heuer TS; Brown PO
    Biochemistry; 1998 May; 37(19):6667-78. PubMed ID: 9578550
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Tn5 transposase as a useful platform to simulate HIV-1 integrase inhibitor binding mode.
    Barreca ML; Ortuso F; Iraci N; De Luca L; Alcaro S; Chimirri A
    Biochem Biophys Res Commun; 2007 Nov; 363(3):554-60. PubMed ID: 17889829
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Diketo acid inhibitor mechanism and HIV-1 integrase: implications for metal binding in the active site of phosphotransferase enzymes.
    Grobler JA; Stillmock K; Hu B; Witmer M; Felock P; Espeseth AS; Wolfe A; Egbertson M; Bourgeois M; Melamed J; Wai JS; Young S; Vacca J; Hazuda DJ
    Proc Natl Acad Sci U S A; 2002 May; 99(10):6661-6. PubMed ID: 11997448
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Hyrtiosal, from the marine sponge Hyrtios erectus, inhibits HIV-1 integrase binding to viral DNA by a new inhibitor binding site.
    Du L; Shen L; Yu Z; Chen J; Guo Y; Tang Y; Shen X; Jiang H
    ChemMedChem; 2008 Jan; 3(1):173-80. PubMed ID: 17943714
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors.
    Kuo CL; Assefa H; Kamath S; Brzozowski Z; Slawinski J; Saczewski F; Buolamwini JK; Neamati N
    J Med Chem; 2004 Jan; 47(2):385-99. PubMed ID: 14711310
    [TBL] [Abstract][Full Text] [Related]  

  • 36. HIV type 1 integrase inhibitors: from basic research to clinical implications.
    Jegede O; Babu J; Di Santo R; McColl DJ; Weber J; QuiƱones-Mateu M
    AIDS Rev; 2008; 10(3):172-89. PubMed ID: 18820719
    [TBL] [Abstract][Full Text] [Related]  

  • 37. C-Terminal Domain of Integrase Binds between the Two Active Sites.
    Roberts VA
    J Chem Theory Comput; 2015 Sep; 11(9):4500-11. PubMed ID: 26575940
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Dissecting Tn5 transposition using HIV-1 integrase diketoacid inhibitors.
    Czyz A; Stillmock KA; Hazuda DJ; Reznikoff WS
    Biochemistry; 2007 Sep; 46(38):10776-89. PubMed ID: 17725323
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome.
    Passos DO; Li M; Yang R; Rebensburg SV; Ghirlando R; Jeon Y; Shkriabai N; Kvaratskhelia M; Craigie R; Lyumkis D
    Science; 2017 Jan; 355(6320):89-92. PubMed ID: 28059769
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structural and dynamical properties of a full-length HIV-1 integrase: molecular dynamics simulations.
    Wijitkosoom A; Tonmunphean S; Truong TN; Hannongbua S
    J Biomol Struct Dyn; 2006 Jun; 23(6):613-24. PubMed ID: 16615807
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.