These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
241 related articles for article (PubMed ID: 22144674)
1. Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling. Warfel NA; Newton AC J Biol Chem; 2012 Feb; 287(6):3610-6. PubMed ID: 22144674 [TBL] [Abstract][Full Text] [Related]
2. Suppression of survival signalling pathways by the phosphatase PHLPP. O'Neill AK; Niederst MJ; Newton AC FEBS J; 2013 Jan; 280(2):572-83. PubMed ID: 22340730 [TBL] [Abstract][Full Text] [Related]
3. Turning off AKT: PHLPP as a drug target. Newton AC; Trotman LC Annu Rev Pharmacol Toxicol; 2014; 54():537-58. PubMed ID: 24392697 [TBL] [Abstract][Full Text] [Related]
4. The phosphatase PHLPP controls the cellular levels of protein kinase C. Gao T; Brognard J; Newton AC J Biol Chem; 2008 Mar; 283(10):6300-11. PubMed ID: 18162466 [TBL] [Abstract][Full Text] [Related]
5. PHLPPing through history: a decade in the life of PHLPP phosphatases. Grzechnik AT; Newton AC Biochem Soc Trans; 2016 Dec; 44(6):1675-1682. PubMed ID: 27913677 [TBL] [Abstract][Full Text] [Related]
6. PHLiPPing the switch on Akt and protein kinase C signaling. Brognard J; Newton AC Trends Endocrinol Metab; 2008 Aug; 19(6):223-30. PubMed ID: 18511290 [TBL] [Abstract][Full Text] [Related]
7. Pleckstrin Homology (PH) Domain Leucine-rich Repeat Protein Phosphatase Controls Cell Polarity by Negatively Regulating the Activity of Atypical Protein Kinase C. Xiong X; Li X; Wen YA; Gao T J Biol Chem; 2016 Nov; 291(48):25167-25178. PubMed ID: 27760826 [TBL] [Abstract][Full Text] [Related]
8. PHLPPing the Script: Emerging Roles of PHLPP Phosphatases in Cell Signaling. Baffi TR; Cohen-Katsenelson K; Newton AC Annu Rev Pharmacol Toxicol; 2021 Jan; 61():723-743. PubMed ID: 32997603 [TBL] [Abstract][Full Text] [Related]
9. Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output. Reyes G; Niederst M; Cohen-Katsenelson K; Stender JD; Kunkel MT; Chen M; Brognard J; Sierecki E; Gao T; Nowak DG; Trotman LC; Glass CK; Newton AC Proc Natl Acad Sci U S A; 2014 Sep; 111(38):E3957-65. PubMed ID: 25201979 [TBL] [Abstract][Full Text] [Related]
10. PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth. Liu J; Stevens PD; Li X; Schmidt MD; Gao T Mol Cell Biol; 2011 Dec; 31(24):4917-27. PubMed ID: 21986499 [TBL] [Abstract][Full Text] [Related]
11. On the PHLPPside: Emerging roles of PHLPP phosphatases in the heart. Lemoine KA; Fassas JM; Ohannesian SH; Purcell NH Cell Signal; 2021 Oct; 86():110097. PubMed ID: 34320369 [TBL] [Abstract][Full Text] [Related]
12. PHLPP Signaling in Immune Cells. Lordén G; Lam AJ; Levings MK; Newton AC Curr Top Microbiol Immunol; 2022; 436():117-143. PubMed ID: 36243842 [TBL] [Abstract][Full Text] [Related]
13. The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer. Li X; Stevens PD; Yang H; Gulhati P; Wang W; Evers BM; Gao T Oncogene; 2013 Jan; 32(4):471-8. PubMed ID: 22391563 [TBL] [Abstract][Full Text] [Related]
14. Photoreceptor Neuroprotection: Regulation of Akt Activation Through Serine/Threonine Phosphatases, PHLPP and PHLPPL. Rajala RV; Kanan Y; Anderson RE Adv Exp Med Biol; 2016; 854():419-24. PubMed ID: 26427440 [TBL] [Abstract][Full Text] [Related]
15. WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1). Gangula NR; Maddika S J Biol Chem; 2013 Nov; 288(48):34545-54. PubMed ID: 24145035 [TBL] [Abstract][Full Text] [Related]
17. Berberine induced modulation of PHLPP2-Akt-MST1 kinase signaling is coupled with mitochondrial impairment and hepatoma cell death. Saxena S; Shukla S; Kakkar P Toxicol Appl Pharmacol; 2018 May; 347():92-103. PubMed ID: 29626488 [TBL] [Abstract][Full Text] [Related]
18. Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes. Lupse B; Annamalai K; Ibrahim H; Kaur S; Geravandi S; Sarma B; Pal A; Awal S; Joshi A; Rafizadeh S; Madduri MK; Khazaei M; Liu H; Yuan T; He W; Gorrepati KDD; Azizi Z; Qi Q; Ye K; Oberholzer J; Maedler K; Ardestani A Cell Rep; 2021 Aug; 36(5):109490. PubMed ID: 34348155 [TBL] [Abstract][Full Text] [Related]
19. Biochemical characterization of the phosphatase domain of the tumor suppressor PH domain leucine-rich repeat protein phosphatase. Sierecki E; Newton AC Biochemistry; 2014 Jun; 53(24):3971-81. PubMed ID: 24892992 [TBL] [Abstract][Full Text] [Related]
20. Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis. Liu J; Weiss HL; Rychahou P; Jackson LN; Evers BM; Gao T Oncogene; 2009 Feb; 28(7):994-1004. PubMed ID: 19079341 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]