235 related articles for article (PubMed ID: 22147697)
1. Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms.
Tardiff DF; Tucci ML; Caldwell KA; Caldwell GA; Lindquist S
J Biol Chem; 2012 Feb; 287(6):4107-20. PubMed ID: 22147697
[TBL] [Abstract][Full Text] [Related]
2. Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy.
Liachko NF; Saxton AD; McMillan PJ; Strovas TJ; Keene CD; Bird TD; Kraemer BC
PLoS Genet; 2019 Dec; 15(12):e1008526. PubMed ID: 31834878
[TBL] [Abstract][Full Text] [Related]
3. TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies.
Cohen TJ; Lee VM; Trojanowski JQ
Trends Mol Med; 2011 Nov; 17(11):659-67. PubMed ID: 21783422
[TBL] [Abstract][Full Text] [Related]
4. Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy.
Liachko NF; Guthrie CR; Kraemer BC
J Neurosci; 2010 Dec; 30(48):16208-19. PubMed ID: 21123567
[TBL] [Abstract][Full Text] [Related]
5. Caspase-cleaved transactivation response DNA-binding protein 43 in Parkinson's disease and dementia with Lewy bodies.
Kokoulina P; Rohn TT
Neurodegener Dis; 2010; 7(4):243-50. PubMed ID: 20551689
[TBL] [Abstract][Full Text] [Related]
6. α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy.
Wong SQ; Pontifex MG; Phelan MM; Pidathala C; Kraemer BC; Barclay JW; Berry NG; O'Neill PM; Burgoyne RD; Morgan A
Neurobiol Dis; 2018 Oct; 118():40-54. PubMed ID: 29940336
[TBL] [Abstract][Full Text] [Related]
7. Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity.
Matlack KE; Tardiff DF; Narayan P; Hamamichi S; Caldwell KA; Caldwell GA; Lindquist S
Proc Natl Acad Sci U S A; 2014 Mar; 111(11):4013-8. PubMed ID: 24591589
[TBL] [Abstract][Full Text] [Related]
8. A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity.
Johnson BS; McCaffery JM; Lindquist S; Gitler AD
Proc Natl Acad Sci U S A; 2008 Apr; 105(17):6439-44. PubMed ID: 18434538
[TBL] [Abstract][Full Text] [Related]
9. Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies.
Miguel L; Frébourg T; Campion D; Lecourtois M
Neurobiol Dis; 2011 Feb; 41(2):398-406. PubMed ID: 20951205
[TBL] [Abstract][Full Text] [Related]
10. TDP-43 potentiates alpha-synuclein toxicity to dopaminergic neurons in transgenic mice.
Tian T; Huang C; Tong J; Yang M; Zhou H; Xia XG
Int J Biol Sci; 2011 Mar; 7(2):234-43. PubMed ID: 21448284
[TBL] [Abstract][Full Text] [Related]
11. TDP-43 toxicity in yeast.
Armakola M; Hart MP; Gitler AD
Methods; 2011 Mar; 53(3):238-45. PubMed ID: 21115123
[TBL] [Abstract][Full Text] [Related]
12. Therapeutic genetic variation revealed in diverse Hsp104 homologs.
March ZM; Sweeney K; Kim H; Yan X; Castellano LM; Jackrel ME; Lin J; Chuang E; Gomes E; Willicott CW; Michalska K; Jedrzejczak RP; Joachimiak A; Caldwell KA; Caldwell GA; Shalem O; Shorter J
Elife; 2020 Dec; 9():. PubMed ID: 33319748
[TBL] [Abstract][Full Text] [Related]
13. CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration.
Liachko NF; McMillan PJ; Guthrie CR; Bird TD; Leverenz JB; Kraemer BC
Ann Neurol; 2013 Jul; 74(1):39-52. PubMed ID: 23424178
[TBL] [Abstract][Full Text] [Related]
14. TDP-1/TDP-43 potentiates human α-Synuclein (HASN) neurodegeneration in Caenorhabditis elegans.
Shen L; Wang C; Chen L; Leung KL; Lo E; Lakso M; Wong G
Biochim Biophys Acta Mol Basis Dis; 2020 Oct; 1866(10):165876. PubMed ID: 32531261
[TBL] [Abstract][Full Text] [Related]
15. Structural transformation of the amyloidogenic core region of TDP-43 protein initiates its aggregation and cytoplasmic inclusion.
Jiang LL; Che MX; Zhao J; Zhou CJ; Xie MY; Li HY; He JH; Hu HY
J Biol Chem; 2013 Jul; 288(27):19614-24. PubMed ID: 23689371
[TBL] [Abstract][Full Text] [Related]
16. Isolating potentiated Hsp104 variants using yeast proteinopathy models.
Jackrel ME; Tariq A; Yee K; Weitzman R; Shorter J
J Vis Exp; 2014 Nov; (93):e52089. PubMed ID: 25407485
[TBL] [Abstract][Full Text] [Related]
17. TDP-43 neurotoxicity and protein aggregation modulated by heat shock factor and insulin/IGF-1 signaling.
Zhang T; Mullane PC; Periz G; Wang J
Hum Mol Genet; 2011 May; 20(10):1952-65. PubMed ID: 21355045
[TBL] [Abstract][Full Text] [Related]
18. Glucocorticoids exacerbate cognitive deficits in TDP-25 transgenic mice via a glutathione-mediated mechanism: implications for aging, stress and TDP-43 proteinopathies.
Caccamo A; Medina DX; Oddo S
J Neurosci; 2013 Jan; 33(3):906-13. PubMed ID: 23325230
[TBL] [Abstract][Full Text] [Related]
19. Review: transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegeneration.
Gendron TF; Josephs KA; Petrucelli L
Neuropathol Appl Neurobiol; 2010 Apr; 36(2):97-112. PubMed ID: 20202122
[TBL] [Abstract][Full Text] [Related]
20. TDP-43: a DNA and RNA binding protein with roles in neurodegenerative diseases.
Warraich ST; Yang S; Nicholson GA; Blair IP
Int J Biochem Cell Biol; 2010 Oct; 42(10):1606-9. PubMed ID: 20601083
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
