These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
176 related articles for article (PubMed ID: 22148173)
1. Identification of novel α4β2-nicotinic acetylcholine receptor (nAChR) agonists based on an isoxazole ether scaffold that demonstrate antidepressant-like activity. Yu LF; Tückmantel W; Eaton JB; Caldarone B; Fedolak A; Hanania T; Brunner D; Lukas RJ; Kozikowski AP J Med Chem; 2012 Jan; 55(2):812-23. PubMed ID: 22148173 [TBL] [Abstract][Full Text] [Related]
2. Chemistry and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Zhang H; Tückmantel W; Eaton JB; Yuen PW; Yu LF; Bajjuri KM; Fedolak A; Wang D; Ghavami A; Caldarone B; Paterson NE; Lowe DA; Brunner D; Lukas RJ; Kozikowski AP J Med Chem; 2012 Jan; 55(2):717-24. PubMed ID: 22171543 [TBL] [Abstract][Full Text] [Related]
3. Discovery of isoxazole analogues of sazetidine-A as selective α4β2-nicotinic acetylcholine receptor partial agonists for the treatment of depression. Liu J; Yu LF; Eaton JB; Caldarone B; Cavino K; Ruiz C; Terry M; Fedolak A; Wang D; Ghavami A; Lowe DA; Brunner D; Lukas RJ; Kozikowski AP J Med Chem; 2011 Oct; 54(20):7280-8. PubMed ID: 21905669 [TBL] [Abstract][Full Text] [Related]
4. Discovery of highly potent and selective α4β2-nicotinic acetylcholine receptor (nAChR) partial agonists containing an isoxazolylpyridine ether scaffold that demonstrate antidepressant-like activity. Part II. Yu LF; Eaton JB; Fedolak A; Zhang HK; Hanania T; Brunner D; Lukas RJ; Kozikowski AP J Med Chem; 2012 Nov; 55(22):9998-10009. PubMed ID: 23092294 [TBL] [Abstract][Full Text] [Related]
5. Chemistry, pharmacology, and behavioral studies identify chiral cyclopropanes as selective α4β2-nicotinic acetylcholine receptor partial agonists exhibiting an antidepressant profile. Part II. Zhang HK; Yu LF; Eaton JB; Whiteaker P; Onajole OK; Hanania T; Brunner D; Lukas RJ; Kozikowski AP J Med Chem; 2013 Jul; 56(13):5495-504. PubMed ID: 23734673 [TBL] [Abstract][Full Text] [Related]
6. Chemistry and pharmacological characterization of novel nitrogen analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-nicotinic acetylcholine receptor-selective partial agonists. Liu J; Eaton JB; Caldarone B; Lukas RJ; Kozikowski AP J Med Chem; 2010 Oct; 53(19):6973-85. PubMed ID: 20822184 [TBL] [Abstract][Full Text] [Related]
7. Dissociation between duration of action in the forced swim test in mice and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380. Caldarone BJ; Wang D; Paterson NE; Manzano M; Fedolak A; Cavino K; Kwan M; Hanania T; Chellappan SK; Kozikowski AP; Olivier B; Picciotto MR; Ghavami A Psychopharmacology (Berl); 2011 Sep; 217(2):199-210. PubMed ID: 21487659 [TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists. Zhang HK; Eaton JB; Fedolak A; Gunosewoyo H; Onajole OK; Brunner D; Lukas RJ; Yu LF; Kozikowski AP Eur J Med Chem; 2016 Nov; 124():689-697. PubMed ID: 27639361 [TBL] [Abstract][Full Text] [Related]
9. Synthesis and structure-activity relationship studies of 3,6-diazabicyclo[3.2.0]heptanes as novel alpha4beta2 nicotinic acetylcholine receptor selective agonists. Ji J; Schrimpf MR; Sippy KB; Bunnelle WH; Li T; Anderson DJ; Faltynek C; Surowy CS; Dyhring T; Ahring PK; Meyer MD J Med Chem; 2007 Nov; 50(22):5493-508. PubMed ID: 17929796 [TBL] [Abstract][Full Text] [Related]
10. Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates. Yamauchi JG; Gomez K; Grimster N; Dufouil M; Nemecz A; Fotsing JR; Ho KY; Talley TT; Sharpless KB; Fokin VV; Taylor P Mol Pharmacol; 2012 Oct; 82(4):687-99. PubMed ID: 22784805 [TBL] [Abstract][Full Text] [Related]
11. Discovery of a novel alpha-7 nicotinic acetylcholine receptor agonist series and characterization of the potent, selective, and orally efficacious agonist 5-(4-acetyl[1,4]diazepan-1-yl)pentanoic acid [5-(4-methoxyphenyl)-1H-pyrazol-3-yl] amide (SEN15924, WAY-361789). Zanaletti R; Bettinetti L; Castaldo C; Cocconcelli G; Comery T; Dunlop J; Gaviraghi G; Ghiron C; Haydar SN; Jow F; Maccari L; Micco I; Nencini A; Scali C; Turlizzi E; Valacchi M J Med Chem; 2012 May; 55(10):4806-23. PubMed ID: 22468936 [TBL] [Abstract][Full Text] [Related]
12. Antidepressant-like effects of nicotinic acetylcholine receptor antagonists, but not agonists, in the mouse forced swim and mouse tail suspension tests. Andreasen JT; Olsen GM; Wiborg O; Redrobe JP J Psychopharmacol; 2009 Sep; 23(7):797-804. PubMed ID: 18583432 [TBL] [Abstract][Full Text] [Related]
13. Synthesis and Behavioral Studies of Chiral Cyclopropanes as Selective α4β2-Nicotinic Acetylcholine Receptor Partial Agonists Exhibiting an Antidepressant Profile. Part III. Onajole OK; Vallerini GP; Eaton JB; Lukas RJ; Brunner D; Caldarone BJ; Kozikowski AP ACS Chem Neurosci; 2016 Jun; 7(6):811-22. PubMed ID: 27035276 [TBL] [Abstract][Full Text] [Related]
14. Synthesis and pharmacological characterization of novel analogues of the nicotinic acetylcholine receptor agonist (+/-)-UB-165. Sharples CG; Karig G; Simpson GL; Spencer JA; Wright E; Millar NS; Wonnacott S; Gallagher T J Med Chem; 2002 Jul; 45(15):3235-45. PubMed ID: 12109907 [TBL] [Abstract][Full Text] [Related]
15. Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. Bodnar AL; Cortes-Burgos LA; Cook KK; Dinh DM; Groppi VE; Hajos M; Higdon NR; Hoffmann WE; Hurst RS; Myers JK; Rogers BN; Wall TM; Wolfe ML; Wong E J Med Chem; 2005 Feb; 48(4):905-8. PubMed ID: 15715459 [TBL] [Abstract][Full Text] [Related]