107 related articles for article (PubMed ID: 22153498)
1. Structural insights into the autoactivation mechanism of p21-activated protein kinase.
Wang J; Wu JW; Wang ZX
Structure; 2011 Dec; 19(12):1752-61. PubMed ID: 22153498
[TBL] [Abstract][Full Text] [Related]
2. A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases.
Pirruccello M; Sondermann H; Pelton JG; Pellicena P; Hoelz A; Chernoff J; Wemmer DE; Kuriyan J
J Mol Biol; 2006 Aug; 361(2):312-26. PubMed ID: 16837009
[TBL] [Abstract][Full Text] [Related]
3. The active conformation of the PAK1 kinase domain.
Lei M; Robinson MA; Harrison SC
Structure; 2005 May; 13(5):769-78. PubMed ID: 15893667
[TBL] [Abstract][Full Text] [Related]
4. Why an A-loop phospho-mimetic fails to activate PAK1: understanding an inaccessible kinase state by molecular dynamics simulations.
Ng YW; Raghunathan D; Chan PM; Baskaran Y; Smith DJ; Lee CH; Verma C; Manser E
Structure; 2010 Jul; 18(7):879-90. PubMed ID: 20637424
[TBL] [Abstract][Full Text] [Related]
5. Crystal structure of the ALK (anaplastic lymphoma kinase) catalytic domain.
Lee CC; Jia Y; Li N; Sun X; Ng K; Ambing E; Gao MY; Hua S; Chen C; Kim S; Michellys PY; Lesley SA; Harris JL; Spraggon G
Biochem J; 2010 Sep; 430(3):425-37. PubMed ID: 20632993
[TBL] [Abstract][Full Text] [Related]
6. Conformational switch and role of phosphorylation in PAK activation.
Buchwald G; Hostinova E; Rudolph MG; Kraemer A; Sickmann A; Meyer HE; Scheffzek K; Wittinghofer A
Mol Cell Biol; 2001 Aug; 21(15):5179-89. PubMed ID: 11438672
[TBL] [Abstract][Full Text] [Related]
7. Solution structures and biophysical analysis of full-length group A PAKs reveal they are monomeric and auto-inhibited in
Sorrell FJ; Kilian LM; Elkins JM
Biochem J; 2019 Apr; 476(7):1037-1051. PubMed ID: 30858169
[TBL] [Abstract][Full Text] [Related]
8. Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics.
Edwards DC; Sanders LC; Bokoch GM; Gill GN
Nat Cell Biol; 1999 Sep; 1(5):253-9. PubMed ID: 10559936
[TBL] [Abstract][Full Text] [Related]
9. Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1.
Vadlamudi RK; Li F; Adam L; Nguyen D; Ohta Y; Stossel TP; Kumar R
Nat Cell Biol; 2002 Sep; 4(9):681-90. PubMed ID: 12198493
[TBL] [Abstract][Full Text] [Related]
10. Oncogenic Dbl, Cdc42, and p21-activated kinase form a ternary signaling intermediate through the minimum interactive domains.
Wang L; Zhu K; Zheng Y
Biochemistry; 2004 Nov; 43(46):14584-93. PubMed ID: 15544329
[TBL] [Abstract][Full Text] [Related]
11. Activation loop phosphorylation modulates Bruton's tyrosine kinase (Btk) kinase domain activity.
Lin L; Czerwinski R; Kelleher K; Siegel MM; Wu P; Kriz R; Aulabaugh A; Stahl M
Biochemistry; 2009 Mar; 48(9):2021-32. PubMed ID: 19206206
[TBL] [Abstract][Full Text] [Related]
12. The mechanism of p21-activated kinase 2 autoactivation.
Wu H; Wang ZX
J Biol Chem; 2003 Oct; 278(43):41768-78. PubMed ID: 12907671
[TBL] [Abstract][Full Text] [Related]
13. Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors.
Gul M; Fakhar M; Najumuddin ; Rashid S
PLoS One; 2019; 14(11):e0225132. PubMed ID: 31738805
[TBL] [Abstract][Full Text] [Related]
14. Spatiotemporal regulation of the Pak1 kinase.
Parrini MC; Matsuda M; de Gunzburg J
Biochem Soc Trans; 2005 Aug; 33(Pt 4):646-8. PubMed ID: 16042564
[TBL] [Abstract][Full Text] [Related]
15. Evaluation of the catalytic mechanism of the p21-activated protein kinase PAK2.
Wu H; Zheng Y; Wang ZX
Biochemistry; 2003 Feb; 42(4):1129-39. PubMed ID: 12549935
[TBL] [Abstract][Full Text] [Related]
16. Role of the p21-activated kinases (PAKs) in influenza A virus replication.
Pascua PN; Lee JH; Song MS; Park SJ; Baek YH; Ann BH; Shin EY; Kim EG; Choi YK
Biochem Biophys Res Commun; 2011 Oct; 414(3):569-74. PubMed ID: 21982772
[TBL] [Abstract][Full Text] [Related]
17. Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation.
Yamaguchi H; Hendrickson WA
Nature; 1996 Dec; 384(6608):484-9. PubMed ID: 8945479
[TBL] [Abstract][Full Text] [Related]
18. Mechanistic studies of the autoactivation of PAK2: a two-step model of cis initiation followed by trans amplification.
Wang J; Wu JW; Wang ZX
J Biol Chem; 2011 Jan; 286(4):2689-95. PubMed ID: 21098037
[TBL] [Abstract][Full Text] [Related]
19. NMR binding and crystal structure reveal that intrinsically-unstructured regulatory domain auto-inhibits PAK4 by a mechanism different from that of PAK1.
Wang W; Lim L; Baskaran Y; Manser E; Song J
Biochem Biophys Res Commun; 2013 Aug; 438(1):169-74. PubMed ID: 23876315
[TBL] [Abstract][Full Text] [Related]
20. Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase.
Cai Z; Chehab NH; Pavletich NP
Mol Cell; 2009 Sep; 35(6):818-29. PubMed ID: 19782031
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
