These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

83 related articles for article (PubMed ID: 22153942)

  • 21. Synthesis and biological evaluation of (phenylpiperazinyl-propyl)arylsulfonamides as selective 5-HT(2A) receptor antagonists.
    Yoo E; Yoon J; Pae AN; Rhim H; Park WK; Kong JY; Park Choo HY
    Bioorg Med Chem; 2010 Feb; 18(4):1665-75. PubMed ID: 20096593
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT₇ receptor antagonists.
    Zajdel P; Kurczab R; Grychowska K; Satała G; Pawłowski M; Bojarski AJ
    Eur J Med Chem; 2012 Oct; 56():348-60. PubMed ID: 22926225
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Design and synthesis of pyridazinone-based 5-HT(2C) agonists.
    Allerton CM; Andrews MD; Blagg J; Ellis D; Evrard E; Green MP; Liu KK; McMurray G; Ralph M; Sanderson V; Ward R; Watson L
    Bioorg Med Chem Lett; 2009 Oct; 19(19):5791-5. PubMed ID: 19716297
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Homology modeling and docking evaluation of aminergic G protein-coupled receptors.
    McRobb FM; Capuano B; Crosby IT; Chalmers DK; Yuriev E
    J Chem Inf Model; 2010 Apr; 50(4):626-37. PubMed ID: 20187660
    [TBL] [Abstract][Full Text] [Related]  

  • 25. 5-HT 2A receptor activation of the external urethral sphincter and 5-HT 2C receptor inhibition of micturition: a study based on pharmacokinetics in the anaesthetized female rat.
    Mbaki Y; Gardiner J; McMurray G; Ramage AG
    Eur J Pharmacol; 2012 May; 682(1-3):142-52. PubMed ID: 22374259
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT(2C) agonists.
    Andrews MD; Green MP; Allerton CM; Batchelor DV; Blagg J; Brown AD; Gordon DW; McMurray G; Millns DJ; Nichols CL; Watson L
    Bioorg Med Chem Lett; 2009 Sep; 19(18):5346-50. PubMed ID: 19692241
    [TBL] [Abstract][Full Text] [Related]  

  • 27. S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: I. A mechanistic characterization.
    Millan MJ; Mannoury la Cour C; Chanrion B; Dupuis DS; Di Cara B; Audinot V; Cussac D; Newman-Tancredi A; Kamal M; Boutin JA; Jockers R; Marin P; Bockaert J; Muller O; Dekeyne A; Lavielle G
    J Pharmacol Exp Ther; 2012 Mar; 340(3):750-64. PubMed ID: 22178752
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Identification of 4-methyl-1,2,3,4,10,10a-hexahydropyrazino[1,2-a]indoles as 5-HT2C receptor agonists.
    Röver S; Adams DR; Bénardeau A; Bentley JM; Bickerdike MJ; Bourson A; Cliffe IA; Coassolo P; Davidson JE; Dourish CT; Hebeisen P; Kennett GA; Knight AR; Malcolm CS; Mattei P; Misra A; Mizrahi J; Muller M; Porter RH; Richter H; Taylor S; Vickers SP
    Bioorg Med Chem Lett; 2005 Aug; 15(15):3604-8. PubMed ID: 15975787
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and structure-activity relationships of a series of benzazepine derivatives as 5-HT2C receptor agonists.
    Shimada I; Maeno K; Kondoh Y; Kaku H; Sugasawa K; Kimura Y; Hatanaka K; Naitou Y; Wanibuchi F; Sakamoto S; Tsukamoto S
    Bioorg Med Chem; 2008 Mar; 16(6):3309-20. PubMed ID: 18083579
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling.
    Berg KA; Dunlop J; Sanchez T; Silva M; Clarke WP
    J Pharmacol Exp Ther; 2008 Mar; 324(3):1084-92. PubMed ID: 18065501
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.
    López-Rodríguez ML; Morcillo MJ; Fernández E; Benhamú B; Tejada I; Ayala D; Viso A; Campillo M; Pardo L; Delgado M; Manzanares J; Fuentes JA
    J Med Chem; 2005 Apr; 48(7):2548-58. PubMed ID: 15801844
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Differential expression of 5-HT(2A) and 5-HT(2C) receptor mRNAs in mice prone, or resistant, to chronic high-fat diet-induced obesity.
    Huang XF; Han M; Storlien LH
    Brain Res Mol Brain Res; 2004 Aug; 127(1-2):39-47. PubMed ID: 15306119
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity.
    Smith BM; Smith JM; Tsai JH; Schultz JA; Gilson CA; Estrada SA; Chen RR; Park DM; Prieto EB; Gallardo CS; Sengupta D; Thomsen WJ; Saldana HR; Whelan KT; Menzaghi F; Webb RR; Beeley NR
    Bioorg Med Chem Lett; 2005 Mar; 15(5):1467-70. PubMed ID: 15713408
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors.
    Egan C; Grinde E; Dupre A; Roth BL; Hake M; Teitler M; Herrick-Davis K
    Synapse; 2000 Feb; 35(2):144-50. PubMed ID: 10611640
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Synthesis and evaluation of 4-(N,N-diarylamino)piperidines with high selectivity to the delta-opioid receptor: a combined 3D-QSAR and ligand docking study.
    Podlogar BL; Poda GI; Demeter DA; Zhang SP; Carson JR; Neilson LA; Reitz AB; Ferguson DM
    Drug Des Discov; 2000; 17(1):34-50. PubMed ID: 10928448
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Mutagenesis analysis of the serotonin 5-HT2C receptor and a Caenorhabditis elegans 5-HT2 homologue: conserved residues of helix 4 and helix 7 contribute to agonist-dependent activation of 5-HT2 receptors.
    Xie J; Dernovici S; Ribeiro P
    J Neurochem; 2005 Jan; 92(2):375-87. PubMed ID: 15663485
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Design, synthesis, and pharmacological evaluation of piperidin-4-yl amino aryl sulfonamides: novel, potent, selective, orally active, and brain penetrant 5-HT₆ receptor antagonists.
    Nirogi R; Shinde A; Daulatabad A; Kambhampati R; Gudla P; Shaik M; Gampa M; Balasubramaniam S; Gangadasari P; Reballi V; Badange R; Bojja K; Subramanian R; Bhyrapuneni G; Muddana N; Jayarajan P
    J Med Chem; 2012 Nov; 55(21):9255-69. PubMed ID: 23006002
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Arene- and quinoline-sulfonamides as novel 5-HT7 receptor ligands.
    Zajdel P; Marciniec K; Maślankiewicz A; Paluchowska MH; Satała G; Partyka A; Jastrzębska-Więsek M; Wróbel D; Wesołowska A; Duszyńska B; Bojarski AJ; Pawłowski M
    Bioorg Med Chem; 2011 Nov; 19(22):6750-9. PubMed ID: 22001327
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structure-activity relationships of phenylalkylamines as agonist ligands for 5-HT(2A) receptors.
    Blaazer AR; Smid P; Kruse CG
    ChemMedChem; 2008 Sep; 3(9):1299-309. PubMed ID: 18666267
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Preparation of piperazine derivatives as 5-HT7 receptor antagonists.
    Yoon J; Yoo EA; Kim JY; Pae AN; Rhim H; Park WK; Kong JY; Park Choo HY
    Bioorg Med Chem; 2008 May; 16(10):5405-12. PubMed ID: 18456500
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.