191 related articles for article (PubMed ID: 22155078)
1. Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: a member of the phospholipase D superfamily.
Gajewski S; Comeaux EQ; Jafari N; Bharatham N; Bashford D; White SW; van Waardenburg RC
J Mol Biol; 2012 Jan; 415(4):741-58. PubMed ID: 22155078
[TBL] [Abstract][Full Text] [Related]
2. Tyrosyl-DNA phosphodiesterase I catalytic mutants reveal an alternative nucleophile that can catalyze substrate cleavage.
Comeaux EQ; Cuya SM; Kojima K; Jafari N; Wanzeck KC; Mobley JA; Bjornsti MA; van Waardenburg RC
J Biol Chem; 2015 Mar; 290(10):6203-14. PubMed ID: 25609251
[TBL] [Abstract][Full Text] [Related]
3. Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.
Comeaux EQ; van Waardenburg RC
Drug Metab Rev; 2014 Nov; 46(4):494-507. PubMed ID: 25327705
[TBL] [Abstract][Full Text] [Related]
4. The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1.
Davies DR; Interthal H; Champoux JJ; Hol WG
Structure; 2002 Feb; 10(2):237-48. PubMed ID: 11839309
[TBL] [Abstract][Full Text] [Related]
5. Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison.
He X; van Waardenburg RCAM; Babaoglu K; Price AC; Nitiss KC; Nitiss JL; Bjornsti MA; White SW
J Mol Biol; 2007 Sep; 372(4):1070-1081. PubMed ID: 17707402
[TBL] [Abstract][Full Text] [Related]
6. A Theoretical Study of Phosphoryl Transfers of Tyrosyl-DNA Phosphodiesterase I (Tdp1) and the Possibility of a "Dead-End" Phosphohistidine Intermediate.
DeYonker NJ; Webster CE
Biochemistry; 2015 Jul; 54(27):4236-47. PubMed ID: 26121557
[TBL] [Abstract][Full Text] [Related]
7. Dysregulated human Tyrosyl-DNA phosphodiesterase I acts as cellular toxin.
Cuya SM; Comeaux EQ; Wanzeck K; Yoon KJ; van Waardenburg RC
Oncotarget; 2016 Dec; 7(52):86660-86674. PubMed ID: 27893431
[TBL] [Abstract][Full Text] [Related]
8. Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages.
Interthal H; Chen HJ; Champoux JJ
J Biol Chem; 2005 Oct; 280(43):36518-28. PubMed ID: 16141202
[TBL] [Abstract][Full Text] [Related]
9. Analysis of human tyrosyl-DNA phosphodiesterase I catalytic residues.
Raymond AC; Rideout MC; Staker B; Hjerrild K; Burgin AB
J Mol Biol; 2004 May; 338(5):895-906. PubMed ID: 15111055
[TBL] [Abstract][Full Text] [Related]
10. The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily.
Interthal H; Pouliot JJ; Champoux JJ
Proc Natl Acad Sci U S A; 2001 Oct; 98(21):12009-14. PubMed ID: 11572945
[TBL] [Abstract][Full Text] [Related]
11. Structure-function studies of a plant tyrosyl-DNA phosphodiesterase provide novel insights into DNA repair mechanisms of Arabidopsis thaliana.
Kim H; Na SH; Lee SY; Jeong YM; Hwang HJ; Hur JY; Park SH; Woo JC; Kim SG
Biochem J; 2012 Apr; 443(1):49-56. PubMed ID: 22214184
[TBL] [Abstract][Full Text] [Related]
12. Tyrosyl-DNA phosphodiesterase (Tdp1) (3'-phosphotyrosyl DNA phosphodiesterase).
Raymond AC; Burgin AB
Methods Enzymol; 2006; 409():511-24. PubMed ID: 16793421
[TBL] [Abstract][Full Text] [Related]
13. Human Tyrosyl-DNA Phosphodiesterase 1 Possesses Transphosphooligonucleotidation Activity With Primary Alcohols.
Dyrkheeva N; Anarbaev R; Lebedeva N; Kuprushkin M; Kuznetsova A; Kuznetsov N; Rechkunova N; Lavrik O
Front Cell Dev Biol; 2020; 8():604732. PubMed ID: 33425909
[TBL] [Abstract][Full Text] [Related]
14. Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening.
Lountos GT; Zhao XZ; Kiselev E; Tropea JE; Needle D; Pommier Y; Burke TR; Waugh DS
Nucleic Acids Res; 2019 Nov; 47(19):10134-10150. PubMed ID: 31199869
[TBL] [Abstract][Full Text] [Related]
15. Catalytic mechanism of the phospholipase D superfamily proceeds via a covalent phosphohistidine intermediate.
Gottlin EB; Rudolph AE; Zhao Y; Matthews HR; Dixon JE
Proc Natl Acad Sci U S A; 1998 Aug; 95(16):9202-7. PubMed ID: 9689058
[TBL] [Abstract][Full Text] [Related]
16. SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity.
Interthal H; Chen HJ; Kehl-Fie TE; Zotzmann J; Leppard JB; Champoux JJ
EMBO J; 2005 Jun; 24(12):2224-33. PubMed ID: 15920477
[TBL] [Abstract][Full Text] [Related]
17. Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy.
Takashima H; Boerkoel CF; John J; Saifi GM; Salih MA; Armstrong D; Mao Y; Quiocho FA; Roa BB; Nakagawa M; Stockton DW; Lupski JR
Nat Genet; 2002 Oct; 32(2):267-72. PubMed ID: 12244316
[TBL] [Abstract][Full Text] [Related]
18. Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening.
Mamontova EM; Zakharenko AL; Zakharova OD; Dyrkheeva NS; Volcho KP; Reynisson J; Arabshahi HJ; Salakhutdinov NF; Lavrik OI
Bioorg Med Chem; 2020 Jan; 28(1):115234. PubMed ID: 31831297
[TBL] [Abstract][Full Text] [Related]
19. Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase 1 DNA-protein crosslinks and 3'-blocking lesions in the absence of tyrosyl-DNA phosphodiesterase 1 (TDP1).
Tsuda M; Kitamasu K; Kumagai C; Sugiyama K; Nakano T; Ide H
DNA Repair (Amst); 2020; 91-92():102849. PubMed ID: 32460231
[TBL] [Abstract][Full Text] [Related]
20. In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation.
Hawkins AJ; Subler MA; Akopiants K; Wiley JL; Taylor SM; Rice AC; Windle JJ; Valerie K; Povirk LF
DNA Repair (Amst); 2009 May; 8(5):654-63. PubMed ID: 19211312
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
