204 related articles for article (PubMed ID: 22156453)
1. Novel therapeutic approach for neurodegenerative pathologies: multitarget iron-chelating drugs regulating hypoxia-inducible factor 1 signal transduction pathway.
Weinreb O; Amit T; Mandel S; Youdim MB
Neurodegener Dis; 2012; 10(1-4):112-5. PubMed ID: 22156453
[TBL] [Abstract][Full Text] [Related]
2. Novel molecular targets of the neuroprotective/neurorescue multimodal iron chelating drug M30 in the mouse brain.
Kupershmidt L; Weinreb O; Amit T; Mandel S; Bar-Am O; Youdim MB
Neuroscience; 2011 Aug; 189():345-58. PubMed ID: 21570450
[TBL] [Abstract][Full Text] [Related]
3. Neuroprotective multifunctional iron chelators: from redox-sensitive process to novel therapeutic opportunities.
Weinreb O; Amit T; Mandel S; Kupershmidt L; Youdim MB
Antioxid Redox Signal; 2010 Sep; 13(6):919-49. PubMed ID: 20095867
[TBL] [Abstract][Full Text] [Related]
4. Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis.
Kupershmidt L; Weinreb O; Amit T; Mandel S; Carri MT; Youdim MB
FASEB J; 2009 Nov; 23(11):3766-79. PubMed ID: 19638399
[TBL] [Abstract][Full Text] [Related]
5. Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway.
Mandel SA; Avramovich-Tirosh Y; Reznichenko L; Zheng H; Weinreb O; Amit T; Youdim MB
Neurosignals; 2005; 14(1-2):46-60. PubMed ID: 15956814
[TBL] [Abstract][Full Text] [Related]
6. Novel multifunctional neuroprotective iron chelator-monoamine oxidase inhibitor drugs for neurodegenerative diseases: in vitro studies on antioxidant activity, prevention of lipid peroxide formation and monoamine oxidase inhibition.
Zheng H; Gal S; Weiner LM; Bar-Am O; Warshawsky A; Fridkin M; Youdim MB
J Neurochem; 2005 Oct; 95(1):68-78. PubMed ID: 16181413
[TBL] [Abstract][Full Text] [Related]
7. Novel bifunctional drugs targeting monoamine oxidase inhibition and iron chelation as an approach to neuroprotection in Parkinson's disease and other neurodegenerative diseases.
Youdim MB; Fridkin M; Zheng H
J Neural Transm (Vienna); 2004 Oct; 111(10-11):1455-71. PubMed ID: 15480846
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer's, Parkinson's, and other neurodegenerative diseases.
Zheng H; Weiner LM; Bar-Am O; Epsztejn S; Cabantchik ZI; Warshawsky A; Youdim MB; Fridkin M
Bioorg Med Chem; 2005 Feb; 13(3):773-83. PubMed ID: 15653345
[TBL] [Abstract][Full Text] [Related]
9. From anti-Parkinson's drug rasagiline to novel multitarget iron chelators with acetylcholinesterase and monoamine oxidase inhibitory and neuroprotective properties for Alzheimer's disease.
Zheng H; Amit T; Bar-Am O; Fridkin M; Youdim MB; Mandel SA
J Alzheimers Dis; 2012; 30(1):1-16. PubMed ID: 22387411
[TBL] [Abstract][Full Text] [Related]
10. Iron dysregulation in Alzheimer's disease: multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents.
Mandel S; Amit T; Bar-Am O; Youdim MB
Prog Neurobiol; 2007 Aug; 82(6):348-60. PubMed ID: 17659826
[TBL] [Abstract][Full Text] [Related]
11. Why should we use multifunctional neuroprotective and neurorestorative drugs for Parkinson's disease?
Youdim MB; Geldenhuys WJ; Van der Schyf CJ
Parkinsonism Relat Disord; 2007; 13 Suppl 3():S281-91. PubMed ID: 18267251
[TBL] [Abstract][Full Text] [Related]
12. Bifunctional drug derivatives of MAO-B inhibitor rasagiline and iron chelator VK-28 as a more effective approach to treatment of brain ageing and ageing neurodegenerative diseases.
Youdim MB; Fridkin M; Zheng H
Mech Ageing Dev; 2005 Feb; 126(2):317-26. PubMed ID: 15621213
[TBL] [Abstract][Full Text] [Related]
13. The potential application of iron chelators for the treatment of neurodegenerative diseases.
Hider RC; Roy S; Ma YM; Le Kong X; Preston J
Metallomics; 2011 Mar; 3(3):239-49. PubMed ID: 21344071
[TBL] [Abstract][Full Text] [Related]
14. Targeting multiple Alzheimer's disease etiologies with multimodal neuroprotective and neurorestorative iron chelators.
Amit T; Avramovich-Tirosh Y; Youdim MB; Mandel S
FASEB J; 2008 May; 22(5):1296-305. PubMed ID: 18048580
[TBL] [Abstract][Full Text] [Related]
15. Multi-target iron-chelators improve memory loss in a rat model of sporadic Alzheimer's disease.
Salkovic-Petrisic M; Knezovic A; Osmanovic-Barilar J; Smailovic U; Trkulja V; Riederer P; Amit T; Mandel S; Youdim MB
Life Sci; 2015 Sep; 136():108-19. PubMed ID: 26159898
[TBL] [Abstract][Full Text] [Related]
16. Novel multifunctional neuroprotective iron chelator-monoamine oxidase inhibitor drugs for neurodegenerative diseases. In vivo selective brain monoamine oxidase inhibition and prevention of MPTP-induced striatal dopamine depletion.
Gal S; Zheng H; Fridkin M; Youdim MB
J Neurochem; 2005 Oct; 95(1):79-88. PubMed ID: 16181414
[TBL] [Abstract][Full Text] [Related]
17. Understanding the Role of Hypoxia Inducible Factor During Neurodegeneration for New Therapeutics Opportunities.
Merelli A; RodrÃguez JCG; Folch J; Regueiro MR; Camins A; Lazarowski A
Curr Neuropharmacol; 2018; 16(10):1484-1498. PubMed ID: 29318974
[TBL] [Abstract][Full Text] [Related]
18. Iron chelation and neuroprotection in neurodegenerative diseases.
Li X; Jankovic J; Le W
J Neural Transm (Vienna); 2011 Mar; 118(3):473-7. PubMed ID: 21161300
[TBL] [Abstract][Full Text] [Related]
19. Hypoxia inducible factor-1 as a target for neurodegenerative diseases.
Zhang Z; Yan J; Chang Y; ShiDu Yan S; Shi H
Curr Med Chem; 2011; 18(28):4335-43. PubMed ID: 21861815
[TBL] [Abstract][Full Text] [Related]
20. Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia.
Calabrese V; Lodi R; Tonon C; D'Agata V; Sapienza M; Scapagnini G; Mangiameli A; Pennisi G; Stella AM; Butterfield DA
J Neurol Sci; 2005 Jun; 233(1-2):145-62. PubMed ID: 15896810
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]