BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 22157762)

  • 1. Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis.
    Osborn-Heaford HL; Ryan AJ; Murthy S; Racila AM; He C; Sieren JC; Spitz DR; Carter AB
    J Biol Chem; 2012 Jan; 287(5):3301-12. PubMed ID: 22157762
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the isoprenoid pathway to abrogate progression of pulmonary fibrosis.
    Osborn-Heaford HL; Murthy S; Gu L; Larson-Casey JL; Ryan AJ; Shi L; Glogauer M; Neighbors JD; Hohl R; Carter AB
    Free Radic Biol Med; 2015 Sep; 86():47-56. PubMed ID: 25958207
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis.
    Murthy S; Adamcakova-Dodd A; Perry SS; Tephly LA; Keller RM; Metwali N; Meyerholz DK; Wang Y; Glogauer M; Thorne PS; Carter AB
    Am J Physiol Lung Cell Mol Physiol; 2009 Nov; 297(5):L846-55. PubMed ID: 19684199
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Platelet-derived growth factor receptor-α and Ras-related C3 botulinum toxin substrate-1 regulate mechano-responsiveness of lung fibroblasts.
    McGowan SE; McCoy DM
    Am J Physiol Lung Cell Mol Physiol; 2017 Dec; 313(6):L1174-L1187. PubMed ID: 28775097
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Control of antiviral innate immune response by protein geranylgeranylation.
    Yang S; Harding AT; Sweeney C; Miao D; Swan G; Zhou C; Jiang Z; Fitzgerald KA; Hammer G; Bergo MO; Kroh HK; Lacy DB; Sun C; Glogauer M; Que LG; Heaton NS; Wang D
    Sci Adv; 2019 May; 5(5):eaav7999. PubMed ID: 31149635
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rac1-mediated mitochondrial H2O2 generation regulates MMP-9 gene expression in macrophages via inhibition of SP-1 and AP-1.
    Murthy S; Ryan A; He C; Mallampalli RK; Carter AB
    J Biol Chem; 2010 Aug; 285(32):25062-73. PubMed ID: 20529870
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis.
    Larson-Casey JL; Murthy S; Ryan AJ; Carter AB
    J Biol Chem; 2014 Dec; 289(52):36204-19. PubMed ID: 25378391
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrial Cu,Zn-superoxide dismutase mediates pulmonary fibrosis by augmenting H2O2 generation.
    He C; Murthy S; McCormick ML; Spitz DR; Ryan AJ; Carter AB
    J Biol Chem; 2011 Apr; 286(17):15597-607. PubMed ID: 21393238
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress.
    Liu Y; Collins C; Kiosses WB; Murray AM; Joshi M; Shepherd TR; Fuentes EJ; Tzima E
    J Cell Biol; 2013 Jun; 201(6):863-73. PubMed ID: 23733346
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
    Tanaka S; Fukumoto Y; Nochioka K; Minami T; Kudo S; Shiba N; Takai Y; Williams CL; Liao JK; Shimokawa H
    Arterioscler Thromb Vasc Biol; 2013 Jul; 33(7):1591-600. PubMed ID: 23640485
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased flux through the mevalonate pathway mediates fibrotic repair without injury.
    Larson-Casey JL; Vaid M; Gu L; He C; Cai GQ; Ding Q; Davis D; Berryhill TF; Wilson LS; Barnes S; Neighbors JD; Hohl RJ; Zimmerman KA; Yoder BK; Longhini ALF; Hanumanthu VS; Surolia R; Antony VB; Carter AB
    J Clin Invest; 2019 Nov; 129(11):4962-4978. PubMed ID: 31609245
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rac1 is dispensable for oocyte maturation and female fertility in vivo.
    Hao JX; Meng TG; Fan LH; Yao YQ
    PLoS One; 2017; 12(5):e0177202. PubMed ID: 28545113
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Angiotensin-II and MARCKS: a hydrogen peroxide- and RAC1-dependent signaling pathway in vascular endothelium.
    Kalwa H; Sartoretto JL; Sartoretto SM; Michel T
    J Biol Chem; 2012 Aug; 287(34):29147-58. PubMed ID: 22773836
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophages.
    Mehta H; Glogauer M; Bécart S; Altman A; Coggeshall KM
    J Biol Chem; 2009 May; 284(18):11882-91. PubMed ID: 19251698
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Endothelial Mitochondrial Preprotein Translocase Tomm7-Rac1 Signaling Axis Dominates Cerebrovascular Network Homeostasis.
    Shi D; Qi M; Zhou L; Li X; Ni L; Li C; Yuan T; Wang Y; Chen Y; Hu C; Liang D; Li L; Liu Y; Li J; Chen YH
    Arterioscler Thromb Vasc Biol; 2018 Nov; 38(11):2665-2677. PubMed ID: 30354240
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways.
    Ma J; Wang Y; Zheng D; Wei M; Xu H; Peng T
    Cardiovasc Res; 2013 Jan; 97(1):77-87. PubMed ID: 23027656
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SP-1 regulation of MMP-9 expression requires Ser586 in the PEST domain.
    Murthy S; Ryan AJ; Carter AB
    Biochem J; 2012 Jul; 445(2):229-36. PubMed ID: 22519702
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The small GTPase Rac1 is a novel binding partner of Bcl-2 and stabilizes its antiapoptotic activity.
    Velaithan R; Kang J; Hirpara JL; Loh T; Goh BC; Le Bras M; Brenner C; Clement MV; Pervaiz S
    Blood; 2011 Jun; 117(23):6214-26. PubMed ID: 21474673
    [TBL] [Abstract][Full Text] [Related]  

  • 19. IRAK-1 contributes to lipopolysaccharide-induced reactive oxygen species generation in macrophages by inducing NOX-1 transcription and Rac1 activation and suppressing the expression of antioxidative enzymes.
    Maitra U; Singh N; Gan L; Ringwood L; Li L
    J Biol Chem; 2009 Dec; 284(51):35403-11. PubMed ID: 19850916
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial catalase overexpressed transgenic mice are protected against lung fibrosis in part via preventing alveolar epithelial cell mitochondrial DNA damage.
    Kim SJ; Cheresh P; Jablonski RP; Morales-Nebreda L; Cheng Y; Hogan E; Yeldandi A; Chi M; Piseaux R; Ridge K; Michael Hart C; Chandel N; Scott Budinger GR; Kamp DW
    Free Radic Biol Med; 2016 Dec; 101():482-490. PubMed ID: 27840320
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.